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To further investigate whether cyclin A played as a key molecular in cell proliferation, HL-60 cells were exposed to different concentrations of hexamethylene bisacetamide.

为了进一步研究cyclin A在白血病细胞增殖中的作用,用在体内、体外均有抗肿瘤作用的六亚甲基二乙酰胺在体外抑制白血病细胞系HL-60增殖,并诱导其分化。

To further investigate their roles in cell proliferation apoptosis and differentiation, three human leukemia cell lines (K562, U937 and HL60) exposed to various concentration of hexamethylene bisacetamide, a potent inducer of differentiation of transformed cells both in vivo and in vitro, were used as an in vitro model for the study of cell proliferation, differentiation and apoptosis.

为了进一步研究cyclin A和p21在白血病细胞增殖,分化,凋亡中的作用,我们用在体内,外均有抗肿瘤作用的药物六亚甲基二乙酰胺在体外抑制白血病细胞株K562,U937和HL60增殖,诱导其分化,成功地建立了与药物干预浓度呈剂量-效应关系的,具有不同增殖,分化,凋亡状况的实验细胞模型。

Chinese patent medicine ; Zilongjin ; hexamethylene bisacetamid ; cell cycle ; oncogenes ; genes ; tumor suppressor

中成药;紫龙金;环六亚甲基二己酰胺;细胞周期;癌基因;基因;肿瘤抑制

In this paper,we used hexamethylene bisacetamide as a inducer to induce human mucoepidermoid carcinoma cell line MEC-1 cells to differentiate in vitro and vivo.The nucleolus organizer regions was investigated by means of the argyrophil technique.

本实验以六亚甲基二乙酰胺作为分化诱导剂,对涎腺粘液表皮样癌MEC-1细胞进行了体内外诱导,并通过银染技术对对照组和HMBA诱导组癌细胞核内核仁组成区的数目、大小及分布特征进行了观察。

When 45% methanol solution containing 0.5 mmol/L hexamethylene tetraamine was used as the pump carrier, the pump flow rate and output pressure achieved 0.58 mL/min and 0.79 MPa at 4950 V, respectively. By using the pump carrier as the mobile phase, benzene and naphthanlene were separated on baseline by the EFA system.

在4950 V的外加电压下,以含0.5 mmol/L六亚甲基四胺的45%甲醇溶液为泵载流,电渗泵的流量和输出压强分别为0.58 mL/min和0.79 MPa,以泵载流为流动相,该系统对苯和萘进行了反相色谱分离。

Objective To investigate the effects of the Chinese drug Zilongjin and hexamethylene bisacetamid on expression of oncogenes(c-ras,c-myc),and tumorsuppressor genes(Rb,p53,p21)of MGc803 cell in cell cycle.

目的 探讨中药紫龙金与环六亚甲基二己酰胺对人胃癌MGc80 3不同周期细胞癌基因c ras、c myc、抑癌基因Rb、p5 3、p2 1以及蛋白激酶PKC a基因表达的影响。方法采用Northernblot印迹法检测基因表达情况。

A hybridized material consisting of polyacrylic acid and kaolin is found to have high water absorbent performance.This polymer/inorganically hybridized material is synthesized by polymerization and cross linking reaction.

在高岭土存在下,以 N,N-亚甲基双丙烯酰胺作交联剂,以过硫酸钾作引发剂,部分中和的丙烯酸单体进行聚合交联反应,合成高聚物/无机杂化高吸水性材料。

Seauckthorn juice can be appropriate drinks afer the diluting, which could block the N-nitroso Synthesis and also can block N-dimethylnitrosaminewhich can lead to cancer.The flavone of Seabuckthorn contains coumarin, isocoumarin, furan coumarins, lignin, as well as bitter polyphenols, 5 - serotonin, which are benefited for anti-cancer.

沙棘汁经稀释成宜引用的浓度后,能阻断N-亚硝酸的合成,另外沙棘汁对致癌物N二甲基亚硝胺也有阻断与防护的作用;沙棘黄酮中含有香豆素,异香豆素,呋喃香豆素,苦木素以及多酚类,5-色胺等具有综合抗癌作用的成分。

The glass transition temperature from DMTA analysis revealed the glass transition temperature of the extragallery cured epoxy resin and was in relation to the curing temperatures. Addition of organophilic montmorillonite led to the disappearance of the α' peak of loss tangent of the nanocomposites.

DMTA测试表明,所测的玻璃化转变温度是层外固化环氧树脂的玻璃化转变温度,并发现二亚乙基三胺固化环氧树脂纳米复合材料的玻璃化转变温度与固化温度紧密相关,且加入蒙脱土后纳米复合材料的低温α'松弛峰消失。

The epoxy resin/diethylenetriamine/montmorillonite nanocomposites were prepared by casting and curing processes and the intercalation behavior of epoxy resin in the organophilic montmorillonite was investigated by XRD and DMTA methods.

采用浇模固化成型法制备了环氧树脂/二亚乙基三胺/蒙脱土纳米复合材料,并用X射线衍射、动态力学热分析法等手段研究了环氧树脂在有机蒙脱土中的插层行为。

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