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亚胺

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Lactam was gained by the Staudinger reaction of imine and olefineketone in the presence of N-heterocyclic carbene catalyst.

以N-杂环卡宾催化剂1催化亚胺与烯酮之间的Staudinger反应,得到相应的β-内酰胺。

3Novel Fluorenyl Cardo chain extended bismaleimideswere synthesized and characterized by reacting maleic anhydride with fluorenyl cardo diamine and different dianhydrides.

通过马来酸酐和芴基Cardo二胺及不同二酐反应,合成了新型的芴基Cardo链延长型双马来酰亚胺

While conducting studies on deamination of commercially available phenethylamines, the scientists found that the intermediate imine can react further to yield aryl-substituted pyrroles 1 in good yields.

在研究上买到phenethylamines酰胺、科学家发现能进一步反应中间体亚胺芳产量取代吡咯-1良好收益。

The cis novel bisoxazoline ligands L1-L4 have been synthesized through the treatment of new cis dihydroxy diamide with p-toluenesulfonyl chloride in the presence of catalytic quantity of 4--pyridine, and the cis dihydroxy diamide could be achieved from the condensation of the amino alcohols and cis cyclopropane dicarbonyl chloride prepared via oxidation and halogenation from cis-2,2-dimethyl-3-formylcyclopropanecarboxylate with DCC.

我们以蒈醛酸内酯为起始原料,经过氧化反应、酰氯化反应得到顺式环丙烷二酰氯,然后在二环己基碳二亚胺的催化下与相应的氨基醇反应合成了顺式二羟基酰胺,再用对甲苯磺酰氯将羟基活化,最后在二甲氨基吡啶的催化下关环合成顺式双噁唑啉配体L1~L4。

The loss or diminishment of OprD2 was the main reason for the imipenem resistance of P.aeruginosa in our hospital, but its effect on meropenem resistance deserved further study.

在对亚胺培南耐药的菌株中,合并有其他β-内酰胺类抗生素耐药的菌株达到62.34%(48/77)。32株Pa外膜蛋白电泳结果显示OprD2相对含量在耐药组为0~3.5%(其中有一株为8.70%),敏感组为6.20%~10.20%。

Results: The proportion of Gram-negative bacilli rose obviously, so did the opportunistic pathogen's and Yeasts detected rate. Most drug sensitive tests showed the drug-fast rate turned to be high. Escherichia coli, Salmonella and Citrobacter resistant and so on to fluoroquinolones was 57%~97%. These bacteria to imipenem showed excellent activity. Meticillin-resistant-staphylococcus resistant to ciprofloxacin, norfloxacin, clindamycin, tetracycline, erythromycin, cefazolin and ampicillin were 40.9%, 42.4%, 63.6%, 72.2%, 85.9%, 100.0% and 100.0%, respectively Streptococcus and Enterococcus resistant to major β-lactams-penicillin, aminoglycosides, macrolides, tetracyclines and sulfonamides were between 36.0% to 100.0%.

结果:革兰阴性杆菌比例显著升高,条件致病菌和酵母样真菌检出机会显著增多;药敏结果显示多数临床细菌对常用抗生素的耐药趋势在不断上升;大肠埃希菌、沙门菌和枸橼酸杆菌等革兰阴性杆菌对喹诺酮类药物的耐药率达57%~97%,亚胺培南则对阴性杆菌有较高的敏感覆盖率;耐甲氧西林葡萄球菌对环丙沙星、诺氟沙星、氯洁霉素、四环素、红霉素、头孢唑啉和氨苄西林的耐药率分别为40.9%、42.4%、63.6%、70.2%、85.9%、100.0%和100.0%;链球菌和肠球菌对多数β内酰胺类青霉素、氨基糖苷类、大环内酯类、四环素类以及磺胺类药物均呈高度耐药,耐药率在36%~100%。

To Dec. 2003 years in Yuxi city People's Hospital. RESULTS: The proportion of G- bacilli were much. The opportunistic pathogen's and Yeasts detected rate rose obviously. Most drug sensitive tests showed the drug-fast rate turned to be high. Escherichia coli, Salmonella and Klebsiella and so on to fluoroquinolones was 50~97.7%. These bacteria to imipenem showed excellent activity. MRS resistant to ciprofloxacin, norfloxacin, clindamycin, tetracycline, erythromycin, gentamycin, trimeth/sulfa and cefazolin were above 50%. Streptococcus resistant to major β-lactams-penicillin, aminoglycosides, macrolides, tetracyclines and sulfonomides were highness.

结果:G-杆菌比例居多,条件致病菌和酵母样真菌检出机会显著增高;药敏结果显示多数临床细菌对常用抗生素的耐药趋势在不断上升;大肠埃希菌、沙门菌和克雷伯菌等G-杆菌对喹诺酮类药物的耐药率在50%~97.7%,亚胺培南则对阴性杆菌有较高的敏感覆盖率;耐甲氧西林葡萄球菌对环丙沙星、诺氟沙星、氯洁霉素、四环素、红霉素、庆大霉素、复方新诺明和头孢唑啉的耐药率均在50%以上,链球菌对多数β内酰胺类青霉素、氨基糖苷类、大环内酯类、四环素类以及磺胺类药物呈高度耐药。

The X-ray structure analysis reveals that the metal is in a square-planar N2O2 coordination environment formed by the phenolate-O, the imine-N and the deprotonated amide-O atoms of hydrazone ligand and the N atom of Himdz.

配合物的晶体结构分析表明,中心金属通过酰腙配体的酚基氧原子、亚胺基氮原子、去质子酰胺氧原子以及咪唑的氮原子形成平面四方形的N2O2配位环境。

The results revealed that the imine mechanism and hydroxylamine mechanism were both existed in the reaction.

结果表明,从量子化学角度分析,环己酮氨肟化反应的亚胺机理和羟胺机理均可以发生。

Moreover,the effects of the linkage of imide/amideon the properties of polyamide-imides were also discussed.

此外,酰亚胺/酰胺链接结构对PAI性能的影响也被讨论。

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