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亚砷酸钠

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Methods 50 mice were divided into control group, sodium arsenite group and sodium arsenate group at random.

50只雄性小鼠被随机分成对照组、亚砷酸钠组和砷酸钠组。

Objective:To investigate the effects of arsenic trioxide on peri-blood T lymphocyte apoptosis in asthmatic and normal person.

目的比较亚砷酸钠对哮喘患者及正常人外周血T细胞体凋亡诱导作用。

Objective To investigate the effect of different concentrations of sodium arsenite on the reactive oxygen species and lipid peroxidate of the lymphocytes of rats cultured in vitro and the antagonism of sodium selenite and vitamin C.

目的 观察不同浓度的亚砷酸钠(NaAsO2)对体外培养的大鼠淋巴活性氧群和细胞内脂质过氧化物含量的影响,并探讨亚硒酸钠(NaSeO3)和维生素C对砷毒性的拮抗作用。

Objective To study the toxic effects of inorganic arsenic on skin fibroblasts proliferation, and to explore the molecular mechanism of sodium arsenite for its role in skin lesions from arsenic contamination.

目的观察亚砷酸钠诱导体外培养的人皮肤成纤维细胞的作用,探讨砷性皮肤损伤的分子机制。

Sodium arsenite can induce oxidative stress,and antioxidants can antagonize the cytotoxicity of arsenic.

亚砷酸钠可引起细胞内氧化应激,抗氧化物可一定程度拮抗砷的细胞毒性作用。

This paper put forward three ways: Oxidation-reduction titration, ferruginous spectrophotometry, and direct spectrophotometry. Every way is applied in PH fit for itself. Every way should pay attention to some ways.

本论文确定高铁酸钾的三种定量分析方法:亚砷酸钠氧化还原滴定法、邻二氮杂菲分光光度法、直接分光光度法,并明确了每种方法的适用PH值范围和应遵守的相应注意事项。

Methods The selected microorganisms were cultivated at 37℃ in culture media with different concentration of sodium arsenite and counted by microscope, and arsenic content in bacteria was detected by ASA.

采用在培养基中加入不同浓度亚砷酸钠的方法研究各菌株对砷的耐受性,并在显微镜下进行细菌量计数,采用超低温捕获原子吸收分光光度仪测定菌体中砷含量。

Results With different concentration of sodium arsenite 0.5 ~ 5.0 μmol/L, the skin fibroblasts were markedly stimulated, and a dose effect relationship was observed.

结果与对照组比较,皮肤成纤维细胞经不同剂量的亚砷酸钠诱导后,吸光度值均有改变,存在剂量效应关系(P〈0.01)。0.5~5.0μmol/L浓度的亚砷酸钠对皮肤成纤维细胞有明显的增殖作用,而10μmol/L浓度的亚砷酸钠产生明显的毒性作用。

The control group drank tap water,the other three groups drank 2.72 mg/L,13.6 mg/L and 68 mg/L solution of sodium arsenite for 3 months.

对照组饮用自来水,砷暴露组分别饮用2.72,13.6和68 mg/L亚砷酸钠溶液。

Sodium arsenite group and sodium arsenate group were made by 300 mg/L per day of sodium arsenite and sodium arsenate respectively. The mice were sacrificed after 10 months for liver function and pathologic examination. The expression of MMp-8, TIMP-2, Col-Ⅰ、Col-Ⅲ mRNA were detected with real time flourescence quantitative PCR. The result was controlled with 18s.

亚砷酸钠组和砷酸钠组给予普通饲料和砷溶液。10个月后处死小鼠,血清进行肝功能检测;苏木素-伊红染色部分肝组织;Trizol-酚-氯仿一步法提取小鼠肝组织总RNA,紫外分光光度法测定总RNA浓度及纯度,实时荧光定量PCR法测肝组织中MMP-8、MMP-2、Col-Ⅰ、Col-Ⅲ mRNA的表达,以18S基因作为质控。

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