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Methods The apoptosis of NB4 cells was studied by flow cytometry, DNA gel electrophoresis and Western blot analysis.

采用流式细胞术、DNA电泳和免疫印迹法研究亚砷酸钠对NB4细胞的作用。

Cases are treated by As2O3 as treatment group and 24 cases are treated by western medicine as control group , then observe the change of the clinical syndrom , peripheral hemogram and myelogram.

治疗组36例,以亚砷酸注射液(10mg)治疗;对照组24例,以西药化疗治疗,观察两组患者疗前和疗后的临床症状、外周血像及骨髓像的变化。

Results When sodium arsenite treatment and cigarette smoke solution treatment were used together or separately, protein expression of Bcl-2 decreased; Protein expression of Bax and the number of apoptotic cells increased.

结果 亚砷酸钠和香烟烟气溶液单独作用或者联合作用都能够使细胞Bcl-2蛋白表达减少、Bax蛋白表达增加、凋亡细胞数增加。

The interactions were synergistic. Conclusion Sodium arsenite and cigarette smoke solution have interactions on protein expression of Bcl-2 and Bax. The interactions are synergistic.

亚砷酸钠和香烟烟气溶液对大鼠淋巴细胞的Bcl-2蛋白表达、Bax蛋白表达的影响存在交互作用,交互作用方式为协同作用。

Methods According to 2×2 factorial design, rat lymphocytes were divided into 4 groups: sodium arsenite treated group, cigarette smoke solution treated group, sodium arsenite and cigarette smoke solution treated group and control group.

按照2×2析因设计将大鼠淋巴细胞分为4组:亚砷酸钠单独作用组、香烟烟气溶液单独作用组、两者联合作用组和对照组。

Methods Cell number counting, MTT reduction assay, transmission electron microscope were performed in skin fibroblasts,and sodium arsenite was used as tester for inorganic arsenics.

方法通过直接细胞计数法和噻唑蓝还原法检测亚砷酸钠对皮肤成纤维细胞生长的影响。

Combined with X-ray Diffraction Analysis, a new pigment-copper acetoarsenite, which were synthesize in Modem times, was also identified in Tibetan murals for the first time, and thus provided scientific data for dating the murals.

此外还利用x射线衍射分析技术,首次发现在西藏壁画制作中使用了近代人工合成的新颜料-乙酰亚砷酸铜,为壁画的保护和制作年代的推定提供了科学数据。

RESULTS : Twenty-five patients were treated with arsenous acid. Among them, 2 4 reached CR (CR rate 96%), 1 no remission.

结果:亚砷酸治疗25例复发急性早幼粒细胞白血病,24例达完全缓解,1例未缓解,缓解率96%。

Arsenous acid/therapeutic use ; Liver neoplasms/drug therapy

亚砷酸盐类/治疗应用;肝肿瘤/药物疗法

AIM: To evaluate the effectiveness of arsenous aci d (As2O3) injectable solution in the treatment of relapsed acute promyelocyti c leukemia.

目的:观察亚砷酸对复发的急性早幼粒细胞白血病的疗效。

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