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Aims: To investigate the roles of arsenious acid (As2O3) on inducing differentiation of hepatoma cell line BEL-7402 and to provide experimental data for clinic utilization.

目的:研究亚砷酸(As_2O_3)是否有诱导肝癌细胞分化的作用并探讨其可能机制,为亚砷酸作为新的诱导分化剂用于肝癌治疗提供科学的实验依据。

Examples are provided by the following preparations: arsenious sulphide from arsenious acid and hydrogen sulphide: gold or silver sols by reduction of the corresponding salts of gold or silver, silver chloride from very dilute solutions of silver nitrate and sodium chloride.

例子由以下准备提供:亚砷硫化物从亚砷酸和氢化硫:金或银sols 由金子或银,银色氯化物对应的盐的减少从非常硝酸银和氯化钠的稀溶液。

Ferric arsenite sulfate is also of recent interest and may prove to be useful in stabilizing arsenic.

含铁的亚砷酸盐和硫酸盐也是新近的关注点并且可以证明对使砷稳定有用。

The principal aqueous forms of arsenic are the arsenite ionAs ??

砷在液体中的主要形态是亚砷酸离子As?

Objective To investigate the effect of different concentrations of sodium arsenite on the reactive oxygen species and lipid peroxidate of the lymphocytes of rats cultured in vitro and the antagonism of sodium selenite and vitamin C.

目的 观察不同浓度的亚砷酸钠(NaAsO2)对体外培养的大鼠淋巴活性氧群和细胞内脂质过氧化物含量的影响,并探讨亚硒酸钠(NaSeO3)和维生素C对砷毒性的拮抗作用。

Sodium arsenite can induce oxidative stress,and antioxidants can antagonize the cytotoxicity of arsenic.

亚砷酸钠可引起细胞内氧化应激,抗氧化物可一定程度拮抗砷的细胞毒性作用。

He activity of y-GT also had dose- dependent and time-dependent effect and became lowest on day 7 at the concentration of 0.5 and 1.0 umol/L. The activity of TAT increased. On day 4, the cells treated with 0.25, 0.5 and 1.0 umol/L of As2O3 had higher activity compared with control group (P.05) and it continued afterwhile.

AT随着各给药组时间的延长而上升,并随给药剂量增大而上升程度更大,培养第4天,0.25 μmol/L浓度的亚砷酸组TAT的比活性较对照组高(P<0.05),0.5 μmol/L、1 μmol/L浓度的亚砷酸组TAT的比活性较对照组更高(P<0.01),以后各天给药组均高于对照组(P<0.01)。

Methods 0, 2.5, 5, 10, 15 and 20 μmol/L arsenious acid-treated human hepatocellular carcinoma HepG2 cells were cultured under hypoxia for 8 hours. The cell proliferation and cell viability was assayed by WST-8 and the trypan blue dye exclusion method. The expressions of HIF-1α in human hepatocellular carcinoma HepG2 cells were checked by RT-PCR and Western Blot.

以0、0.25、0.5、1、2和4μmol/L的亚砷酸处理人肝癌细胞HepG2缺氧环境中培养8h;1μmol/L的亚砷酸处理人肝癌细胞HepG2缺氧培养0~10h,WST-8法和台盼蓝染色法分析细胞增殖和活力,采用RT-PCR和Western Blot方法检测肝癌细胞中HIF-1α的表达。

The structure of ArsA ATPase with its ligand, arsenite, either on membranes or in solution, was revealed. The current trimeric ring-like structure of this protein doubts the previous dimeric model and gives deeper insight on this protein's physiological roles.

对亚砷酸根复合体ArsA蛋白质分子结构的揭示显示了该蛋白在亚砷酸根存在情况下,在膜上和水溶液中都是环形三聚体,对前人的二聚体模型假说提出了置疑,并为解释它的生理功能提供了重要的结构信息。

The results showed that Acidithiobacillus ferrooxidans could effectively solubilise realgar and 16.3% arsenic dissolution could be achieved in 30 days under the conditions of pH 1.8 in Iron free 9 K medium (with additional 1.0g of ferrous iron per liter and 0.5% of realgar), 150 rpm, 30°C. The trace elements of Zn, Cu, Mg, Mn, Fe and Se et al. could also be effectively leached.

实验结果表明,氧化亚铁硫杆菌能够有效溶解雄黄中不溶性的硫化砷,30 ℃,pH1.8,以20%接种量接种驯化后的氧化亚铁硫杆菌BY-3条件下135r/min摇瓶浸出30天砷的溶出率可达16.3%,Zn、Cu、Mg、Mn、Fe、Se等有益微量元素都能够得到有效浸出。

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这一模式非常关注商人的网络信用基础。

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