互变异构

By studying the absorption spectra, we have verified the existence of various tautomers of sodium fluorescein in ethanol solution.

通过对其吸收光谱的研究，证明荧光素钠在乙醇溶液中存在多种互变异构体。

The calculated results indicate that water in two of them can protect formamide from tautomerizing, while in the third one works oppositely, exactly the same as the situations in gas phase.

使用B3LYP密度范函的计算方法，在B3LYP/6-311++G**的基组条件下运用SCRF溶液模型研究了溶液环境对甲酰胺互变异构的影响。

This invention provides compounds of Formula; wherein: R is a moiety selected from the group: and n is an integer of 1 or 2; R is selected from hydrogen, amino,-NRR, alkyl of 1 to 12 carbon atoms optionally substituted, aryl of 6, 10 or 14 carbon atoms optionally substituted, alkenyl of 2 to 12 carbon atoms optionally substituted, alkynyl of 2 to 12 carbon atoms optionally substituted, halogen, and a 5 to 10 membered heteroaryl ring optionally substituted, having 1 to 4 heteroatoms independently selected from N, O and S; R is selected from hydrogen, alkyl of 1 to 12 carbon atoms optionally substituted, aryl of 6, 10 or 14 carbon atoms optionally substituted, alkenyl of 2 to 12 carbon atoms optionally substituted, vinyl, alkynyl of 2 to 12 carbon atoms optionally substituted and halogen; R is H, alkyl of 1 to 12 carbon atoms optionally substituted, cycloalkyl of 3 to 8 carbon atoms, bicycloalkyl of 5 to 10 carbon atoms or aralkyl optionally substituted; R is OH or -OH; R and R are each independently H or alkyl of 1 to 12 carbon atoms or when optionally taken together with the nitrogen atom to which each is attached form a 3 to 8 membered saturated heterocyclyl ring; R is alkyl of 1 to 12 carbon atoms optionally substituted; or a tautomer or pharmaceutically acceptable salts thereof.

本发明提供式的化合物；其中：R 1 为选自基团和的部分；n为整数1或2；R 2 选自氢、氨基、-NR 6 R 7 、具有1到12个碳原子的视情况经取代的烷基、具有6个、10个或14个碳原子的视情况经取代的芳基、具有2到12个碳原子的视情况经取代的烯基、具有2到12个碳原子的视情况经取代的炔基、卤素和具有1到4个独立地选自N、O和S的杂原子的视情况经取代的5元到10元杂芳基环；R 3 选自氢、具有1到12个碳原子的视情况经取代的烷基、具有6个、10个或14个碳原子的视情况经取代的芳基、具有2到12个碳原子的视情况经取代的烯基、乙烯基、具有2到12个碳原子的视情况经取代的炔基和卤素；R 4 为H、具有1到12个碳原子的视情况经取代的烷基、具有3到8个碳原子的环烷基、具有5到10个碳原子的双环烷基或视情况经取代的芳烷基；R 5 为OH或-OH 8 ；R 6 和R 7 各自独立地为H或具有1到12个碳原子的烷基，或当视情况与其所连接的氮原子连接在一起时形成3元到8元饱和杂环基环；R 8 为具有1到12个碳原子的视情况经取代的烷基；或其互变异构体或医药学上可接受的盐。

The forming mechanism of dihydrophenophosphazine by the interaction of Ph〓NH and PCl〓 was studied, and the possible forming mechanism of spiro phosphonium chloride in the same reaction system was also proposed.

讨论了二苯胺与三氯化磷的成环机理以及反应过程中螺磷杂环化合物的形成机制，提出5，10-二氢磷杂吖嗪-10-氧化物存在类"烯醇—酮式"互变异构现象。

OH -Tautomer more stable and predicted to predominate in gas phase.

羟基互变异构体更加稳定和预测天然气占主导的阶段。

There is little evidence to support the general supposition that the NH -tautomer is generally favoured see Wang et.

很少有证据支持的一般假定的新罕布什尔州，互变异构体普遍赞成

General Statement一般性发言 OH -Tautomer more stable and predicted to predominate in gas phase.

羟基互变异构体更加稳定和预测天然气占主导的阶段。

Two potential wells are found. One corresponds to the normal cytosine, while the other corresponds to its imino tautomer.

发现有两个势阱：其中一个对应正常的胞嘧啶，而另一个则对应它的顺式亚胺式互变异构体。

However, poly analogs cannot be obtained through the polymerization of the obvious parent molecule, vinyl amine, because vinyl amine is unstable with respect to its imine tautomer, ethylimine.

然而，聚类似物不能获得通过聚合明显的母公司分子，乙烯胺，因为乙烯胺是不稳定与尊重其亚胺互变异构体， ethylimine 。

Tautomerism: Existence of two or more chemical compound s that have the same chemical composition but different structures and that convert easily from one to another.

互变异构体现象：两种或多种化合物，具有相同的化学组成，但结构不同，很容易从一种转换到另一种。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！