二钠的

This rock zone, with a NE striking, the whole length of 1 400 km and the width of 100～150 km, is characterized by not onlyalkaline rocks (analcite biotite olivine melilitites, leucititic alnoites, nephelite syenites, aegirite augite syenites, melanite syenites, riebeckite syenite and aegirite bearing quartz syenites) and alkaline granite (riebeckite granite, and aegitite augite riebeckite granite), but also a lot of syenites, monzonites and alkaline feldspar granites or miarolitic K feldspar granites.

该岩带全长约1400km，宽100～150km，不仅发育有狭义的碱性岩(方沸黑云橄榄黄长岩、白榴黄长煌斑岩、霞石正长岩、霓辉石正长岩、黑榴石正长岩和含霓石石英正长岩)和碱性花岗岩(钠闪石花岗岩、霓辉石钠闪石花岗岩)，还发育有大量的正长岩类二长岩类碱长花岗岩或晶洞钾长花岗岩。

Two magnetic triphase catalysts of comb-like polyether s supported by γ-Fe2O3 were synthesized, and their catalytic behaviors in the iodo-substitution, etherization and the addition reaction of dichlo-rocarbene to styrene were also investigated.

以表面经偶联剂修饰的γ-Fe2O3为载体，通过聚分别与乙二醇单甲醚和一缩二乙二醇单甲醚的醇钠盐反应，合成了两种磁性梳状聚醚三相相转移催化剂，研究了它们在碘代、二氯卡宾对双键加成和混合醚制备反应中的催化活性。

Process for the manufacture of a dialkylphenylethylmalonatewhich comprises adding to a quantity of sodium which is covered with a hydrocarbon solvent boiling above 100°C, at least a chemically equivalent proportion of methyl, ethyl or a propyl alcohol, subsequently adding an approximately equivalent proportion of a dialkylcarbonate and of an alkyl phenylacetate, the alkyl groups in these two last-mentioned compounds being preferably the same as the alkyl radical of the above –mentioned lower aliphatic alcohol, heating the mixture to induce reaction and continually distilling out the alcohol formed from the reaction zone and finally causing the sodio diethyl phenylmalonate so formed to interact with an ethylating agent.

生产二烷基苯基丙二酸酯的工艺过程：这包括这包括把至少处于化学平衡的甲醇，乙醇或丙醇添加到覆盖着沸点超过一百摄氏度的碳氢化合物溶剂中，接着加入大约相同当量的二烷基碳酸酯和烷基乙酸苯酯，在刚才提到的化合物中，其烷基集团最好是和刚才提到的低级别脂肪族醇相同，然后加热反应混合物从而引导反应的进行，在反应区域通过连续蒸馏移除形成的醇类。最后使所形成的钠代二乙基苯基丙二酸酯和乙基化试剂反应。

Cycloalkylation of diethyl malonate and ethyl cyanoacetate with alkyl halide was investigated in the presence of toluene.

以甲苯为溶剂及带水剂，用粉末K2CO3代替常规使用的乙醇钠，在季铵盐和聚乙二醇混合相转移催化剂的存在下，含有活泼氢的丙二酸二乙酯和氰乙酸乙酯与二卤代物进行缩合反应，得到相应的环化物。

RESULTS: All aromatic anesthetics inhibited I at a holding potential which produce half-maximal current V(1/2; inhibition was modest with 1,3,5-trifluorobenzene (8%+/- 2%), pentafluorobenzene (13%+/- 2%), and hexafluorobenzene (13%+/- 2%), but greater with benzene (37%+/- 2%), fluorobenzene (39%+/- 2%), 1,2-difluorobenzene (48%+/- 2%), 1,4-difluorobenzene (31 +/- 3%), and 1,2,4-trifluorobenzene (33%+/- 1%).

结果：在最高电流的一半的控制电压下所有芳香族麻醉药都阻断钠电流；均苯三酚（8%+/- 2%）、戊苯(13%+/- 2%)、戌苯(13%+/- 2%)的抑制是适度的比苯(37%+/- 2%)、氟苯(39%+/- 2%)，1.2-二氟二苯(48%+/- 2%)，1，4-二氟二苯(31 +/- 3%)，和1，2，4三氟苯(33%+/- 1%)明显。

Methods This study contained a total of 16 culture groups, including one group as control and 5 groups treated by 5 drugs (calcium L-threonate, sodium L-threonate, alendronate, 17β-estradiol and calcium gluconate) each at the final concentrations of 10^(-9)mol/L, 10^(-7)mol/L, 10^(-5)mo1/L respectively. After 7 days, eight bone slices of every group were stained with toluidine blue and the areas of resorptive pits were analyzed under light microscope; the concentrations of C-telopeptide of type Ⅰ collagen CT(subscript x or Crosslaps in culture supernatants were measured by ELISA.

制备骨磨片，培养OC，并分别加入高中低浓度10^(-5、10^(-7)、10^(-9)mol/L的L-苏糖酸钙、L-苏糖酸钠、阿仑麟酸钠、17β-雌二醇、葡萄糖酸钙，实验设以上各浓度组及对照组（共16组，每组n=8），甲苯胺蓝染色一光镜观察分析骨片上骨吸收陷窝面积，ELISA测定上清液Ⅰ型胶原C-末端肽（CTx或Crosslaps）浓度。

Itamin D from the skin and diet is metabolized in the lier to 25-hydroxyitamin D (Figure 1), which is used to determine a patient's itamin D status1,2,3,4; 25-hydroxyitamin D is metabolized in the kidneys by the enzyme 25-hydroxyitamin D-1-hydroxylase (CYP27B1) to its actie form, 1,25-dihydroxyitamin D.1,2,3,4 The renal production of 1,25-dihydroxyitamin D is tightly regulated by plasma parathyroid hormone leels and serum calcium and phosphorus leels.1,2,3,4 Fibroblast growth factor 23, secreted from the bone, causes the sodium–phosphate cotransporter to be internalized by the cells of the kidney and small intestine and also suppresses 1,25-dihydroxyitamin D synthesis.5 The efficiency of the absorption of renal calcium and of intestinal calcium and phosphorus is increased in the presence of 1,25-dihydroxyitamin D (Figure 1).2,3,6 It also induces the expression of the enzyme 25-hydroxyitamin D-24-hydroxylase (CYP24), which catabolizes both 25-hydroxyitamin D and 1,25-dihydroxyitamin D into biologically inactie, water-soluble calcitroic acid.2,3,4

从皮肤和食物来的维生素D在肝中代谢为25-羟基维生素D（图1），被用来决定病人体内维生素D情况的1，2，3，4；25-羟基维生素D在肾中被25-羟基维生素D1羟化酶（CYP27B1）转变为有活性的1，25-二羟基维生素D 。1，2，3，4由肾产生1，25-二羟基维生素D是被血浆甲状旁腺激素和血清钙，磷水平紧密调节。1，2，3，4由骨分泌的成纤维细胞生长因子23使钠磷协同转运蛋白被肾和小肠细胞内化及抑制1，25-二羟维生素D合成。5 在1，25-二羟基维生素D作用下肾和小肠吸收钙及磷的效率增高(图1)。2，3，6 它也包括25-羟四- 24 -羟化酶的表达(CYP24)，且将1，25二羟基维生素D和25羟基维生素D异化成无生物活性，水溶性的维生素D3-23羧酸。2，3，4

The synthetic technique of anionic surfactant sodium dodecyl diphenyl ether disulfonate was studied.The best reaction conditions were determined.Alkylation was carried out with n∶ n=5∶1 at 70 ℃ for 5 h to attain 82% yield.

研究了十二烷基二苯醚二磺酸钠阴离子表面活性剂的合成工艺，得出烷基化的最佳反应条件为：催化剂用量为n∶n =5∶1；反应时间 5h ；反应温度 70℃；二苯醚的转化率 82 %。

The main reason for the deactivation is that the catalysts react directly with methyl formate produced to form alkali formates (sodium formate and potassium formate) and diemthyl ether.

导致催化剂活性降低的主要原因是甲醇钠可以直接与产物甲酸甲酯反应形成甲酸钠和二甲醚。

ABSTRACT: In the presence of sodium t-butoxide and DMSO,ethyl 2-oxocyclopentanecarboxylate was subjected to C-alkylation with 2-(4-bromomethylphenyl)propanoic acid with high regioselectivity to give 2-［4-(1-ethoxycarbonyl-2-oxo-1-cyclopentanylmethyl)phenyl］propanoic acid (4) which was followed by hydrolysis,decarboxylation and salt formation to afford loxoprofen sodium in about 72% overall yield.

在叔丁醇钠和二甲基亚砜的存在下，2-丙酸对2-乙氧羰基环戊酮进行C-烷基化，再经水解脱羧，成盐即得洛索洛芬钠，以2-丙酸计算，总收率为72%。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。