二酰亚胺

For the advantages of mild reaction conditions,DDC condensation method and acyl chloride esterification method are much more popular.

由于具有反应条件温和的优点，二环己基碳二亚胺脱水缩合法和酰氯酯化法是目前国内外最常用的两种方法。

Through using Mythylene DinitrAmine as rude product, the knowledge of its reaction properties in different phases have been increased, Through using Mythylene BisAcetAmide as rude product, intermediates which include 1,3-Diacetyl -4,5-dihydroxy -1,3-diazacyclopentane and 1,3-Diacetyl- 4,5-diacetoxy-l,3-diaza cyclopentane have been obtained. 2,4,6,8-tetracetyl- 2,4,6,8-tetraaza bicyclo[3,3,0]octane which can be used to produce Bicyclo-HMX by nitrolysis was also produced. Through using Mythylene BisFormAmide as rude product, intermediates which include 1,3-Diformyl-4,5-dihydroxy- 1,3-diazacyclopentane and 1,3-Diformyl- 4,5-diacetoxy-l,3-diazacyclopentane have been abtained.

以亚甲基二硝胺为初始原料，加深了对亚甲基二硝胺在不同反应相反应特征的认识；以亚甲基二乙酰胺为初始原料，制备了中间体1，3-二乙酰基-4，5-二羟基-1，3-二氮杂环戊烷和1，3-二乙酰基-4，5-二乙酰氧基-1，3-二氮杂环戊烷，最终制备了可被直接硝解为双环HMX的2，4，6，8-四乙酰基-2，4，6，8-四氮杂双环[3，3，0]辛烷；以亚甲基二甲酰胺为初始原料，制备了中间体1，3-二甲酰基-4，5-二羟基-1，3-二氮杂环戊烷和1，3-二甲酰基-4，5-二乙酰氧基-1，3-二氮杂环戊烷。

The process is carried out by taking organic acid and sulfoxide chloride as raw materials, acyl chloride synthesizing, reacting ethylenediamine with sodium chloroacetate to synthesize intermediate sodium EDDA, and reacting it with acyl chloride to synthesize the final product.

所述双子烷基羧酸盐表面活性剂是由以下方法制得的，以有机酸和氯化亚砜为原料首先进行酰氯的合成，再用乙二胺与氯乙酸钠反应合成中间体乙二胺二乙酸钠，将中间体乙二胺二乙酸钠与酰氯反应合成终产物。

Methods GAMP was activated with cyanogen bromide and combined with 1, 6-adipic acid dihydrazide. The prepared polysaccharide derivative GAMP-ADH was coupled to recombinant protein Pep10 with N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride.

GAMP经溴化氰活化后，共价接合己二酰肼手臂，在碳二亚胺催化下与重组蛋白Pep10偶联，制备结合物GAMP-ADH-Pep10。

Rare precious metals company mainly engaged in electroplating and metal surface treatment, environmental treatment, washed clean of raw materials: silver nitrate, nitric acid and rhodium, palladium nitrate; Asia selenium acid, selenium dioxide, tellurium dioxide, mineral selenium powder Japan, Mitsubishi Se powder, Mitsui, Sumitomo, emerging, Germany selenium powder; molybdenum trioxide, DMF; TX-10, NP-9 series, EDTA series; sodium hypophosphite, nickel nitrate, metal thallium, rhodium, palladium, platinum , Beryllium, Ritek, zirconium products; sponge palladium; electrolytic nickel, nickel corner, hydrazine hydrate, Ultra-fine silver, nano-silver; Thallium sulfate, iodized Thallium sulfate, nickel, copper sulfate, copper chloride, copper oxide, nickel oxide , Lanthanum oxide, oxidation Er, bismuth oxide, bismuth ingots, tin ingots, indium ingot, indium foil, Xinding, zinc powder; SnCl2, sulfate-tin; hydrofluoric acid, white Vaseline, propylene glycol, dichloro Methane, the propylene glycol, triethanolamine, triethanolamine oleic acid soap, chloroform, pyrophosphate copper, Gioia sodium, polyacrylamide, PAC, oleic acid, Glycerol, phosphate and other domestic and imported chemical series.

公司主要经营稀贵金属及电镀金属表面处理、环保污水处理、洗涤清洗原料：硝酸银、硝酸铑、硝酸钯；亚硒酸、二氧化硒、二氧化碲、日本矿业硒粉、三菱硒粉、三井、住友、新兴、德国硒粉；三氧化钼、二甲基甲酰胺；TX－10、NP-9系列、EDTA系列；次亚磷酸钠、硝酸镍、金属铊、铑、钯、铂、铍、铼、锆系列产品；海绵钯；电解镍、镍角、水合肼、特细银粉、纳米银粉；硫酸铊、碘化铊、硫酸镍、硫酸铜、氯化铜、氧化铜、氧化镍、氧化镧、氧化铒、氧化铋、铋锭、锡锭，铟锭、铟箔、锌锭，锌粉；氯化亚锡、硫酸亚锡；氢氟酸、白凡士林、丙二醇，二氯甲烷，二丙二醇，三乙醇胺、三乙醇胺油酸皂、三氯甲烷、焦磷酸铜、焦亚硫酸钠、聚丙烯酰胺、聚合氯化铝、油酸、甘油、磷酸等国产、进口化工系列。

It was discovered that proteases, lipases and abzymes can be used for the regioselective acylation of sucrose.

酶催化合成蔗糖酯通常在N，N-二甲基甲酰胺，二甲基亚砜和吡啶等有毒溶剂中进行。

This dissertation is mainly focused on the reactivity of methylenecyclopropanes and comprises six parts. 1 The reactions of methylenecyclopropanes with phenylsulfenyl chloride, phenylselenyl chloride and diphenyl diselenide; 2 The coupling reactions of the ring-opening products derivated from methylenecyclopropanes; 3 The palladium-catalyzed ring-enlargement of mono-aryl group substituted methylenecyclopropanes to cyclobutenes. 4 The gold-catalyzed domino ring-opening and ring-closing hydroamination of methylenecyclopropanes with sulfonamides; 5 The Lewis acid-catalyzed reactions of mono-aryl group substituted methylenecyclopropanes with diethyl ketomalonate in the presence of water; 6 The iodobenzene diacetate mediated novel 1,3-dipolar cycloaddition of methylenecyclopropanes, vinylidenecyclopropanes, and methylenecyclobutane with phthalhydrazine.

本论文主要研究了亚甲基环丙烷类化合物的一些化学反应性能，共由以下六部分组成：1、亚甲基环丙烷类化合物与苯硫氯、苯硒氯及二苯基二硒的反应；2、亚甲基环丙烷类化合物开环产物的偶联反应；3、单芳基取代的亚甲基环丙烷类化合物在钯催化剂作用下的扩环反应；4、金化合物催化磺酰胺对亚甲基环丙烷类化合物的串联开环关环氨氢化反应；5、路易斯酸催化亚甲基环丙烷类化合物与丙酮二羧酸二乙酯在有水存在下的反应；6、醋酸碘苯促进的亚甲基环丙烷类化合物、亚乙烯基环丙烷类化合物及亚甲基环丁烷类化合物与邻苯二甲酰肼的新型1，3-偶极环加成反应。

Methods Activate groups A and C meningococcal polysaccharide with cyanogens bromide and prepare into MenAPS-ADH and MenCPS-ADH derivatives by reacting with 1, 6-adipic acid dihydrazine. Mix MenAPS-ADH and MenCPS-ADH derivatives with purified tetanus toxoid at a certain mass ratio, then add l-ethyl-3(3-dimethylaminopropyl)-carbodiimide to prepare bulks of MenAPS-TT and MenCPS-TT conjugates respectively. Mix the two bulks at a certain ratio, add stabilizer and lyophilize to prepare group A+C meningococcal polysaccharide conjugate vaccine.

A群和C群脑膜炎球菌多糖在溴化氰的活化下，以1，6己二酰肼作为连接子，与精制破伤风类毒素在碳二亚胺作用下结合，再按一定的比例将两者混合，制成A+C群脑膜炎球菌多糖结合疫苗原液，加保护剂冻干后，制成A+C群脑膜炎球菌多糖结合疫苗。

The results showed that dimethyl sulphoxide and formamide were not rational choices for gel spinning process of high-relative viscosity nylon 6 when m- cresol, sulfonic acid and form.

结果表明：二甲基亚砜和甲酰胺不宜作高相对粘度尼龙6的冻胶纺丝溶剂，硫酸、甲酸和间甲酚比较适宜；提高温度有利于降低剪切速率，质量分数为12％的间甲酚溶液和质量分数为9％的甲酸溶液作溶剂，其尼龙6溶液分别在50～60℃和45℃以上有较好的可纺性；溶剂对尼龙6晶体结构的形成有着重要的影响。

Peptides are traditionally synthesized in liquid phase, such methods are DCC, mixed anhydrides, acyl chloride and azide etc., which provide more choices for peptides synthesis.

传统的肽类合成多采用液相化学合成，常用的包括碳二亚胺法，混合酸酐法、酰氯法、叠氮物法等等，为多肽的合成提供了多种选择。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。