二色性的

Two kinds of water-soluble biomimetic chitosan derivatives with a phosphoramide linkage between glucosamine and choline were prepared through Atherton-Todd reaction under the mild conditions, including zwitterionic phosphorylcholine bound chitosan and acetyl-phosphorylcholine bound chitosan with positive charge. The interaction between chitosan derivatives and calf thymus DNA were inversigated by UV alsorption spectra and circular dichroism spectra.

采用Antherton-Todd反应制备了两种水溶性的磷酰化壳聚糖仿生衍生物：两性的N-磷酸胆碱磷酰化壳聚糖和带正电荷的N-乙基磷酸胆碱磷酰化壳聚糖，并用紫外吸收光谱和圆二色光谱研究了两种胆碱磷酰化壳聚糖衍生物与小牛胸腺DNA的相互作用。

The Cardo structure could increase the solubility and thermal stability of the resultant polyimide.

通过在聚酰亚胺的主链中引入庞大侧基（9，9-二苯基芴）形成轴状聚酰亚胺，同时提高聚酰亚胺的溶解性和热稳定性；庞大的侧基又能阻止链的堆砌，避免生色团荧光链间淬灭；通过加入第二种二酐单体合成三元缩聚型聚酰亚胺，调控荧光性二酐在聚酰亚胺中的含量，降低生色团在聚酰亚胺中的浓度，来避免生色团荧光浓度淬灭，增加聚酰亚胺的固态荧光量子效率；通过使用热稳定性好的稠环生色团苝和吖啶来避免共轭类生色团（如含双键或三键的生色团）在高温下热交联及氧和水的破坏。

The conclusions were as follows: theνO-H andνC=O IR absorption maxima shifted towards higher wave numbers after imprinting 17β-estradiol on TFMAA-co-TRIM copolymer with the red shift of theνO-H groups being apparent after precipitation polymerization for 16h while that forνC=O groups being observed after polymerization for 24h. A strong interaction between TFMAA and 17β-estradiol was confirmed by the high selectivity for 17β-estradiol, as indicted by the values of the separation factor of isomers of 17β-estradiol/17α-estradiol (2.28) and the imprinted factor (3.01). Particle diameter of TFMAA-co-TRIM polymer was between 300 nm and 1.5μm, which suited well for solid phase sorbent throughout at low column pressure. The recognition of imprinting TFMAA-co-TRIM polymer for sterol molecules was driven by enthalpy eluted with acetronitile, and low temperature was in favor of the separation of sterol structure analogues on imprinting column. TFMAA-co-TRIM polymer possessed of determinate anti-heat stability, with melting point beginning at 255.84℃, Tp=257.40℃, control TFMAA-co-TRIM polymer and imprinting TFMAA-co-TRIM polymer were respectively decompounded at 267.79℃and 343.11℃, and solid micro-extraction noddle prepared by the special polymerization also showed definite recognition for 17β-estradiol by GC/MS detecting at 270℃. By selection of various washing and elution solvents, elution reagents of close polymerization system were of more advantage in template molecules retention and recognition on molecularly imprinted solid phase extraction column. At a certain extent, progesterone, 17α-estradiol, 17β-estradiol and 4-androstene-3, 17-dione could be intercepted on the MISPE column. Especially, MISPE had high selectivity for progesterone, and imprinting TFMAA-co-TRIM polymer could achieve adsorption balance within 50 min by absorption kinetics test for 17β-estradiol. However, MISPE column showed better selectivity and enrichment property for 17β-estradiol than C18 and CSPE columns according to the data from HPLC and GC/MS analyses. Recovery of 17β-estradiol on MISPE column was up to 85.5% while when prime extracting solution of milk powder was sampled, the recovery of CSPE and C18 columns were 43.7% and 30.7%, respectively.

通过研究阐明：紫外聚合产物TFMAA-co-TRIM中的νO-H振动吸收峰在聚合16h后红移，νC=O振动吸收峰在聚合24h后红移；TFMAA-co-TRIM对雌二醇异构体的印迹因子达到了3.01，α为2.28，优于其它功能单体参与得到的聚合物识别特性；TFMAA-co-TRIM聚合物粒径介于300 nm至1.5μm之间，作为色谱固定相具有良好的通量和低的柱压；在乙腈流动相中，TFMAA-co-TRIM分子印迹固定相的分离过程主要被焓驱动，低温有利于分子印迹固定相分离甾醇结构类似物；TFMAA-co-TRIM分子印迹聚合物在255.84℃时开始熔融，Tp=257.40℃，聚合物CP的降解温度在267.79℃，MIP降解温度在343.11℃，制备的固相微萃取头初步经GC/MS 270℃的耐热性测定；不同的洗提溶剂筛选证明了选择接近聚合溶剂的洗脱体系更有利于MISPE发挥识别效应；分子印迹固相萃取柱对孕酮、17α-雌二醇、17β-雌二醇和雄烯二酮都具有不同程度的保留特性，可作为此类化合物的吸附材料，特别对孕酮强保留的富集特性，可作为孕酮的选择性识别吸附剂，其分子印迹聚合物对17β-雌二醇的吸附动力学测定显示在50 min内基本达到吸附平衡，具有作为传感器核心敏感材料的潜力；对比萃取奶粉中17β-雌二醇性能，MISPE柱比非分子印迹固相萃取柱和C18柱具有更高的保留，回收率依次为85.5%，43.7%和30.7%。

Objective To develop a RP-HPLC method for the enantiomeric separation of indapamide on a new chiral column CHIRALCEL OD-RHcellulose tris(3,5-dimethylphenylcarbamatecoated on a5μm silica-gel substratefor pharmaceutical study of indapamide.Methods To obtain optimistic method for the enantiomeric separation of indapamide,the inferences of the composition of mobile phase,the flow rate and the temperature on the enantiomer retentivity and selectivity were examined and discussed.

目的采 用新型反相手性色谱柱CHIRALCEL OD-RH(纤维素3，5-二甲基苯基氨基甲酸酯涂敷在5μm硅胶上)，建立吲达帕胺对映体的反相高效液相色谱拆分方法，为研究吲达帕胺手性对映体药代动力学提供基础。

The separation of optical isomers of 2, 2'-dihydroxy-1, 1'-binaphthyl and 2, 2'-diamino-1, 1'-binaphthyl was studied by reversed-phase high performance liquid chromatography on a chiral stationary phase consisting of-hydroxypropyl-β-cyclodextrin (Cyclobond Ⅰ 2000 SP)using methanol/water as the mobile phase. The effects of mobile phase ratio, flow rate and column temperature on separation of optical isomers of DHBN and DABN were investigated.

在S-羟丙基－β-环糊精手性柱(CyclobondⅠ2000 SP)上用反相高效液相色谱法研究了2，2'-二氨基－1，1'-联萘和2，2'-二羟基－1，1'-联萘光学异构体的分离，考察了流动相组成、流速以及柱温等对联二萘胺和联二萘酚光学异构体分离的影响。

To study the bioactive components from water soluble extract of the Chinese eaglewood, various column chromatography of Chinese eaglewood led to the isolation of ten compounds. Their structures were elucidated as 2,3-bis(3-hydroxyphenyl)- propan-1-ol (1), [(2R,3R)-3-(4-amino-3,5-dimethoxyphenyl)oxiran-2-yl]methanol (2), 8-chloro-4'- methoxy-5,6,7,3'-tetrahydroxy-2-(2-phenethyl)-5,6,7,8-tetrahydrochromone (3), 4'-methoxy-5,6,7,3'-tetrahydroxy-2--5,6,7,8-tetrahydrochromone (4), the isomer of 4 (5), 4'-methoxy-5,6,7,8-tetrahydroxy-2-(3'-hydroxyphenethyl)-5,6,7,8- tetrahydrochromenone (6), 4'-methoxyisoagarotetrol (7), 6-hydroxy-2-(2-hydroxy-2- phenethyl)-chromone (8), 6-hydroxy-2-(2-phenethyl)-chromone (9), 6-hydroxy-2-(4'- hydroxy-2-phenethyl)-chromone (10), and Guaiacylacetone (11) by means of spectral analysis and comparison with references.

为了进一步发现沉香中具有生理活性的化学成分，本文对国产沉香的水溶性成分进行了研究，从中分离得到11个化合物，通过红外、紫外、质谱、核磁共振(1H-NMR， 13C-NMR， COSY， HSQC， HMBC， ROESY)波谱解析，分别鉴定为：2，3-二(3-羟基苯基)-丙-1-醇(1)，[(2R，3R)-3-(4-氨基-3，5-二甲氧苯基)-2-氧化烯基]甲醇(2)，8-氯-4'-甲氧基-5，6，7，3'-四羟基-2-(2-苯乙基)-5，6，7，8-四氢色原酮(3)，4'-甲氧基-5，6，7，3'-四羟基-2-(2-苯乙基)-5，6，7，8-四氢色原酮(4)，化合物3的差向异构体(5)，4'-甲氧基-5，6，7，8-四羟基-2-(3'-羟基-2-苯乙基)-5，6，7，8-四氢色原酮(6)，4'-甲氧基异沉香四醇(7)，6-羟基-2-(2-羟基-2-苯乙基)色原酮(8)，6-羟基-2-(2-苯乙基)色原酮(9)，6-羟基-2-(4'-羟基-2-苯乙基)色原酮(10)和Guaiacylacetone (11)。

In present study, a liquid-liquid extraction method was employed to extract the volatile components in mulberry fruit sparkling wine. The analysis with gas chromatography-mass spectrometry detected 69 peaks, among which 63 volatile components were identified. The first 9 volatile components with high relative content were benzyl alcohol, 2-methyl-1-butanol, mono-(2-ethylhexyl)-1, 2-benzene dicarboxylic acid, 3-methyl-1-butanol, toluene, acrylic acid butyl ester, 1H-indole-3-ethanol, isodecyl octyl phthalate and decyl octyl phthalate.

采用液－液萃取法提取桑椹汽酒中的挥发性成分，经气相色谱－质谱联机分析，共检测出69个峰，鉴定出63种挥发性化合物，其相对含量排在前9位的挥发性化合物分别是苯乙醇、2-甲基－1-丁醇、1，2-苯二酸单（2-乙基）己酯、3-甲基－1-丁醇、甲苯、丙烯酸丁酯、1H-吲哚－3-乙醇、邻苯二甲酸异癸基辛基二酯、邻苯二甲酸癸基辛基二酯。

Scanning electron microscopy,transmission electron microscopy,circular dichroism and small-angle X-ray diffraction were used to analyze the aggregation mode of CSG in the organogel phase.A hierarchical self-assembly model was proposed to explain the transition from molecular to primary and secondary structure.It is shown from our results that CSG can aggregate into a micellar fibril nanostructure with high length-to-width ratio which is bundled and entangled to form a three-dimensional(3D) network that immobilize the fluid component probably by surface tension.Moreover,sol-gel polymerization of tetraethoxysilane was carried out using CSG in the gel phase.

通过扫描电镜(ScanningElectron Microscopy，SEM)、透射电镜(Transmission Electron Microscopy，TEM)、圆二色谱(Circular Dichroism，CD)和小角X—射线衍射仪(Small-angle X-rayDiffraction，SAXRD)考察CSG分子自组装行为结果表明，CSG形成的聚集体具有多级结构：首先CSG通过手性堆叠自组装形成直径在9—10nm的细纳米纤维，这些细的纳米纤维再以不规则的六方堆积的方式进行排列，构成直径在40—100nm的粗纳米纤维(即细纳米纤维的&捆束&)，最后粗纳米纤维互相粘连形成三维网络状结构，使有机溶剂&固定&，从而形成凝胶；以CSG有机凝胶为模板，四乙氧基硅烷为前体，通过溶胶—凝胶聚合的方法制备了直径大约为100nm的二氧化硅纳米管。3。

In the contaminated lard sample, 6 organic compounds have been thus identified to be the raw materials or byproducts in the production of organic tin compounds. Based on the identified contaminants, it can be postulated that the chemical structure of the organic tin compound is dibutyltin-bis-(2-isooctyl thioacetate). The method is simple and precise, and has not been reported in the local literature.Keywords Organic tin compound, Lard, SPME－GC－MS

经过摸索研究，采用固相微萃取方法富集挥发性杂质，直接注入色谱中，经色谱分离，质谱测定，确定了杂质的结构，由杂质成分推断生产有机锡所用的原料，然后判断合成路线，最后确定有机锡的结构，从有毒猪油中鉴定出2－巯基醋酸异辛酯、双（2－醋酸异辛酯）二硫、双醋酸异辛酯硫醚等6种与有机锡有关的杂质，并与相应的有机锡工业品对照，发现工业品中也含有这些杂质，与其合成过程的原料及副产物相符，从而确定有机锡化合物为二硫代醋酸异辛酯二丁基锡。

Two chiral stationary phases, phenyl isocyanate teicoplanin CSP and 3,5-dimethylphenyl isocyanate teicoplanin CSP were prepared from the macrocyclic glycopeptide teicoplanin CSP using derivative agents, phenyl isocyanate or 3,5-dimethylphenyl isocyanate, respectively.

用大环抗生素替考拉宁手性固定相分别与3，5-二甲基苯基异氰酸酯和苯基异氰酸酯反应得到了两种新型的高效液相色谱手性固定相----3，5-二甲基苯基异氰酸酯替考拉宁手性固定相和苯基异氰酸酯替考拉宁手性固定相。

Finally, according to market conditions and market products this article paper analyzes the trends in the development of camera technology, and designs a color night vision camera.

最后根据市场情况和市面上产品的情况分析了摄像机技术的发展趋势，并设计了一款彩色夜视摄像机。

Only person height weeds and the fierce looks stone idles were there.

只有半人深的荒草和龇牙咧嘴的神像。