二聚的

A pair of primers that contained flanking hydropathic amino acid codons were synthesized, to amply the sequence coding for 10~34 aa in the precursor sequence. The amplified fragment was inserted into pRSET-A to generate the first double repeat of the precursor gene. By utilizing a pair of isocaudamer BamH I and Bgl II sites, and another downstream Hind III site of plasmid pRSET-A, following a series of simple double digestions and ligation of the resulted products, a series of repeat (3, 4 and 6) precursor peptide fragment genes were derived.

本实验设计一对两侧含编码疏水性氨基酸密码子的引物，经过扩增前导序列10~34aa基因序列，并重新克隆入质粒pRSET-A构建串联二聚体后，再利用质粒pRSET-A的BamH I / Bgl II同尾酶克隆位点，经一系列简单的酶切和连接，快速构建这一前导肽中不含组氨酸标签序列的串联多聚体基因，并成功表达其六聚体重组蛋白。

Access to the catalytic center and an unusual switch I movement in the dimeric structure support this finding.

二聚体中催化中心的入口和一种不寻常的开关运动支持了这一猜想，即易位子复合物之间的相互作用或蛋白质前体的潜在结合位点都是由这种二聚体的结构特点决定的。

In addition, our data indicated that the conformation of NR1 subunit homodimers was affected by the partner NR2 subunits during the formation of heteromeric receptor complexes, which might underlie the mechanism by which NR2 subunits modify NMDA receptor function. We also found that in the endoplasmic reticulum, even the whole extracellular N-terminal domain was truncated, the NR subunit could form homomers or heteromers with each other in HEK293 cells, which indicate that the NT is not the crucial element for the receptor assembly.

同时，通过推算FRmax，我们发现NR亚单位同二聚体的N端构象在形成功能性受体的前后是发生变化的，特别是对于NR1a亚单位，其同二聚体的N端构象会因与其配对的NR2亚单位的不同而发生不同的改变。

Erve growth factor combined with its receptor, activated Ras - MAP kinase , mitogen - activated protein kinase kinase is the important regulating factor that make IkB kinase, IKK, phosphated, IkB kinase make the IκBα:(the subunit of NF -κB ) phosphated, the phosphated IkBα degraded, and p65 - p50 heterodimer can be formed, then the heterodimer translocated to nucleus and combined with the promoter domain or other consensus sequence.

GF与其受体相结合，最后可以激活Ras-有丝分裂激活的蛋白激酶途径，有丝分裂激活的蛋白酶激酶(MEKK1)是IγB激酶发生磷酸化的重要调节因子，IKK使NF-κB的亚单位IKBα发生磷酸化，磷酸化的IKBα发生降解，而最后留下p65-p50二聚体，该二聚体然后转位到细胞核内与κB基因的增强子区域或与他的顺式作用序列结合。

A series of copper halides in one, two, or three dimensions have been successfully synthesized such as rhomboid dimers of stoichiometry [Cu2X2L2]n, the tetranuclear species on cubane or stepped cubane tetramers of stoichiometry [Cu4X4L4]n and hexagonal[Cu6X6] grid chains.2 The main strategy in crystal engineering is a secondary building block approach.3 For a given building block, there are two routes to construct frameworks.

在一维、二维或三维的一系列卤化铜已经成功地得到了合成，比如化学计量法[Cu2X2L2]n的长菱形二聚物、化学计量法[Cu4X4L4]n和六边形[Cu6X6]网格链的在立方烷上的四核类或阶梯式立方烷四聚物。[2] 在晶体工程上的主要策略是一种次级构件途径。[3] 对于一给定的构件来说，有两条构件骨架的路线。

But the yields decreased to 71~37％ in n-propanol, i-propanol and i-butanol, with another trimeric byproduct 1-oxo-13c-(2-naphthyloxy)-1, 13c-dihydro-dibenzo xanthenes (29) increasing up to 30％ yield.

而在正丙醇、异丙醇和异丁醇中二苯并咕吨4~6的产率下降至71~37％，另一个二聚体副产物1-氧代-13c-（2-萘氧基）-1，13c-二氢-二苯并-咕吨（29）的含量增加，产率可达30％。

It is concluded that the infrared photodissociation spectroscopy of protonated serine clusters H+n, n = 2 8, provides evidence for a size-dependent transition from neutral to zwitterionic network structures.

第四章的结论中提到由此一系列由二至八的丝胺酸团簇红外吸收光谱结果，我们观察到从二聚体的中性丝胺酸单位到八聚体的两性离子单位，中间经历了结构转换的过程。

It has confirmed that the reactive terminated polyethylene glycols did participate into the curing reaction and construct the soft segments in the crosslinking network.

此外，聚乙二醇的加入还使不饱和聚酯固化反应的活化能明显提高；而改性聚乙二醇的加入，却不影响体系固化反应的活化能。

Systemic levels of IL-6, IL-8 and TNF- a increase in patients with acute pancreatitis and correlate with the severity of the disease.A key regulator of cytokine induction is the pleiotropic transcription factor nuclear factor- K B.

核因子-κB(nuclear factor-kappa B，NF-κB)是由Rel蛋白家族成员形成的同源或异源二聚体，它几乎存在所有的细胞，不同的二聚体与不同的DNA序列结合，亲和力和转录激活能力是不一样的。

10EV and 100eV bombardments have two different influences on the behavior of surface atoms.

10eV、100eV粒子的轰击对表面原子的行为有两方面的影响：一方面，增强了表面原子形成二聚体的能力，使表面二聚体成键数量增加；另一方面，也使表面原子排列无序程度增加，非晶化倾向变得明显。

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。