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Based on the biochemical analysis of the two proteins in vitro, the results of yeast two-hybrid experiment and protein-interaction in both wild type cells and C48 strain, we conclude HetR can form a homodimer through the Cys48 residue. We also show that the dimerization is required for heterocyst differentiation.

基于体外两种蛋白的性质比较和酵母双杂交的结果,并结合相应蓝细菌野生型和突变株C48A中HetR蛋白性质的体内研究表明:HetR蛋白可以通过第48位半胱氨酸残基形成共价结合的同源二聚体,该同源二聚体是异型胞正常分化所必需的。

The high levels of Ddimer is related to the severity of vascular damage in KD.

D二聚体在川崎病血管损伤发生、发展中有着密切的关系。D二聚体的升高反映了川崎病存在明显的高凝状态和血栓形成倾向。

The study on acetoin crystallization dimer showed that the yield of acetoin-dimer was affected by the optical rotation of acetoin.

对乙偶姻二聚体结晶的研究表明,乙偶姻的旋光值对二聚体的结晶得率影响很大,旋光值越接近于零,结晶得率越高。

Cyclopentadiene monomer is not stable and undergoes spontaneous Diels-Alder addition to produce the dimer and higher polymers.

环茂二烯单体是不稳定的,它会自发进行Diels-Alder加成反应,产生二聚体和更高的多聚体。

Access to the catalytic center and an unusual switch I movement in the dimeric structure support this finding.

二聚体中催化中心的入口和一种不寻常的开关运动支持了这一猜想,即易位子复合物之间的相互作用或蛋白质前体的潜在结合位点都是由这种二聚体的结构特点决定的。

In addition, our data indicated that the conformation of NR1 subunit homodimers was affected by the partner NR2 subunits during the formation of heteromeric receptor complexes, which might underlie the mechanism by which NR2 subunits modify NMDA receptor function. We also found that in the endoplasmic reticulum, even the whole extracellular N-terminal domain was truncated, the NR subunit could form homomers or heteromers with each other in HEK293 cells, which indicate that the NT is not the crucial element for the receptor assembly.

同时,通过推算FRmax,我们发现NR亚单位同二聚体的N端构象在形成功能性受体的前后是发生变化的,特别是对于NR1a亚单位,其同二聚体的N端构象会因与其配对的NR2亚单位的不同而发生不同的改变。

Erve growth factor combined with its receptor, activated Ras - MAP kinase , mitogen - activated protein kinase kinase is the important regulating factor that make IkB kinase, IKK, phosphated, IkB kinase make the IκBα:(the subunit of NF -κB ) phosphated, the phosphated IkBα degraded, and p65 - p50 heterodimer can be formed, then the heterodimer translocated to nucleus and combined with the promoter domain or other consensus sequence.

GF与其受体相结合,最后可以激活Ras-有丝分裂激活的蛋白激酶途径,有丝分裂激活的蛋白酶激酶(MEKK1)是IγB激酶发生磷酸化的重要调节因子,IKK使NF-κB的亚单位IKBα发生磷酸化,磷酸化的IKBα发生降解,而最后留下p65-p50二聚体,该二聚体然后转位到细胞核内与κB基因的增强子区域或与他的顺式作用序列结合。

The result expressed that under the concentration of 0.2mg/mL, the 6 compounds are all active to Sarcina lutea, ME-1, MT-6, MT-land MT-7 are active to Bacillus megaterium, to Escherichia coli, only MT-2 is active. The dimeric natural products are intensively existed in botany, most of them have the obvious biological activities. They have been concentrated on in recent years, and they are one of the compounds to which are enjoyed great popularity in natural product.

结果表明,在浓度为0.2mg/mL的条件下,六种化合物对藤黄八叠球菌均具有明显抑制作用,ME-1、MT-6、MT-1、MT-7对巨大芽孢杆菌有抑制作用,MT-2对大肠杆菌有抑制作用,对绿脓杆菌和枯草芽孢杆菌六种成分均无抑制作用;二聚体化合物在植物界广泛存在,多数二聚体天然产物具有显著的生物活性,引起人们的重视,是天然产物化学界研究的热门化合物之一。

It is concluded that the infrared photodissociation spectroscopy of protonated serine clusters H+n, n = 2 8, provides evidence for a size-dependent transition from neutral to zwitterionic network structures.

第四章的结论中提到由此一系列由二至八的丝胺酸团簇红外吸收光谱结果,我们观察到从二聚体的中性丝胺酸单位到八聚体的两性离子单位,中间经历了结构转换的过程。

Systemic levels of IL-6, IL-8 and TNF- a increase in patients with acute pancreatitis and correlate with the severity of the disease.A key regulator of cytokine induction is the pleiotropic transcription factor nuclear factor- K B.

核因子-κB(nuclear factor-kappa B,NF-κB)是由Rel蛋白家族成员形成的同源或异源二聚体,它几乎存在所有的细胞,不同的二聚体与不同的DNA序列结合,亲和力和转录激活能力是不一样的。

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Lao Qiu is the Chairman of China Qiuyang Translation Group and the head master of the Confucius School. He has committed himself to the research and promotion of the classics of China.

老秋先生为中国秋阳翻译集团的董事长和孔子商学院的院长,致力于国学的研究和推广。