二羟苯乙酸
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Water,c12-20 acid peg-8 ester,caprylic/capric triglyceride,proplylene glycol,ppg-15 stearyl ether,chondrus crispus,iris germanica(orris extract/cells),centaurea cyanus,macadamia ternifolia,buxus chinensis,triethanolamine,potassium cetyl phosphate,butyrospermum parkii,c12-13 alkyl lactate,carbomer,phenoxyethanol,methylparaben,imidazolidinyl urea,glyceryl hydroxystearin,tocopheryl acetate.retinyl palmitate,sodium hyaluronate,biosaccharide gum-1,propylparaben,disodium edta,ethylparaben,pentadecalactone,hydroxystearic acid,tetradecyloctadecanoic acid,tetradecyleicosanoic acid,hexadecyleicosanoic acid,butylparaben,isobutylparaben,chlorhexidine digluconate,tocopherol,lecithin,ascorbyl palmitate,glyceryl stearate,glyceryl oleate,BHT,citric acid.
水,C12-20 酸 PEG-8酯,辛酸/癸酸三酸甘油酯,丙二醇,PPG-15 硬脂基醚,卡拉胶萃取,德国鸢尾花提取物/细胞,矢车菊提取物,澳洲坚果油,荷荷巴油,三乙醇胺,十六烷基磷酸钾,牛油果,c12-13烷醇乳酸酯,卡波姆,苯氧乙醇,羟苯甲酯,尿素醛,甘油羟基硬脂酸酯,醋酸盐维他命E,维他命A酯,透明质酸钠,多醣物质,羟苯丙酯,乙酸乙二胺二钠,羟苯乙酯,环十五内酯,羟基硬脂酸,十四烷基十八烷酸,十四烷基二十烷酸,十六烷基二十烷酸,羟苯丁酯,对羟基苯甲酸异丁酯,洗必泰葡萄糖酸盐,维生素E,卵磷脂,抗坏血酸棕榈酸酯,甘油硬脂酸,甘油油酸酯,BHT,柠檬酸。水:几乎所有护肤品成分第一位都是水。辛酸/癸酸三酸甘油酯:润滑剂、扩散剂,棕榈油/椰子油衍生物
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Water,dimethicone,propylene glycol,glycerin,cyclomethicone,ppg-15 stearyl ether,sorbitan oleate,stearic acid,cetyl alcohol,glyceryl stearate,ethylhexyl methoxycinnamate,peg-100 stearate,panthenol,phenoxyethanol,phospholipids,triethanolamine,methylparaben,oenothera biennis oil,imidazolidinyl urea,carbomer,c12-13 alkyl lactate,glycyrrhetinic acid,citrus aurantium dulcisoil,propylparaben,tocopheryl acetate,benzophenone-3,triclosan,disodium edta,ethylparaben,pentadecalactone,iris germanica root extract,retinyl palmitate,bisabolol,butylparaben,sodium hyaluronate,aesculus hippocastanumseed extract,ruscus aculeatus root extract,chlorhexidine digluconate,biosaccharide gum-1,citrus aurantium amaraoil,tocopherol,lecithin,ascorbyl palmitate,glyceryl oleate,BHT,citric acid,limonene,linalool
水, 地美司康,丙二醇,甘油,环甲硅脂, PPG-15 硬脂基醚,油酸己六酯,硬脂酸,十六醇,甘油硬脂酸, 4-甲氧基肉桂酸-2-乙基己基酯,聚乙二醇硬脂酸酯,维生素B5,苯氧乙醇,磷脂质,三乙醇胺,羟苯甲酯,月见草油,尿素醛,卡波姆, c12-13烷醇乳酸酯,甘草亭酸,甜橙油,羟苯丙酯,醋酸盐维他命E,二苯酮-3,玉洁新,乙酸乙二胺二钠,羟苯乙酯,环十五内酯,鸢尾花根萃取,维他命A酯,没药醇,羟苯丁酯,透明质酸钠,欧洲七叶树籽萃取,假叶树根萃取,洗必泰葡萄糖酸盐,多醣物质,苦橙油,维生素E,卵燐脂,抗坏血酸棕榈酸酯,甘油油酸酯,二丁基羟基甲苯,柠檬酸,柠檬精油,芳樟醇水:几乎所有护肤品成分第一位都是水。地美司康:即silicon,矽灵,一般添加于霜剂中,使用后皮肤手感光滑。该成分不可吸收。
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Water,propylene glycol,butylene glycol,glyceryl polymethacrylate,peg-7 glyceryl cocoate,biosaccharide gum-1,phenoxyethanol,hydroxyethylcellulose,ppg-26-buteth-26,chondrus crispus,peg-40 hydrogenated castor oil,sodium hydroxide,methylparaben,benzophenone-4,disodium edta,citrus aurantium dulcisoil,sorbic acid,butylparaben,ruscus aculeatus root extract,glycyrrhiza glabraroot extract,aesculus hippocastanumseed extract,pentadecalactone,iris germanica root extract,rentinyl palmitate,tocopheryl acetate,sodium hyaluronate,citrus aurantium amaraoil,sorbitol,propylparaben,ethylparaben,limonene,linalool,yellow 5,red 4,red 33
水,丙二醇,丁二醇,甘油聚甲基丙烯酸酯,PEG-7 椰子油酸单甘酯,多醣物质,苯氧乙醇,羟乙基纤维素,PPG-26-丁醇聚醚-26,卡拉胶,PEG-40氢化蓖麻油,氢氧化钠,羟苯甲酯,二苯酮-4,乙酸乙二胺二钠,甜橙油,山梨酸,羟苯丁酯,假叶树根萃取,甘草根萃取,欧洲七叶树籽萃取,环十五内酯,鸢尾花根萃取,维他命A酯,醋酸盐维他命E ,透明质酸钠,苦橙油,山梨醇,羟苯丙酯,羟苯乙酯,柠檬精油,芳樟醇,黄5,红4,红33水:几乎所有护肤品成分第一位都是水。丁二醇:保湿剂及溶剂,质地温和
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Water,propylene glycol,butylene glycol,glyceryl polymethacrylate,ascorbic acid,peg-7 glyceryl cocoate,biosaccharide gum-1,peg-40 hydrogenated castor oil,ppg-26-buteth-26,phenoxyethanol,hydroxyethylcellulose,xanthan gum,methylparaben,pentadecalactone,citrus aurantium dulcisoil,disodium edta,sorbic acid,tocopheryl acetate,butylparaben,retinyl palmitate,iris germanica root extract,sodium hyaluronate,ethylparaben,propylparaben,citrus aurantium amara oil,limonene,linalool
水,丙二醇,丁二醇,甘油聚甲基丙烯酸酯,维生素C衍生物,PEG-7 椰子油酸单甘酯,多醣物质,PEG-40氢化蓖麻油,PPG-26-丁醇聚醚-26,苯氧乙醇,羟乙基纤维素,山羊胶,羟苯甲酯,环十五内酯,甜橙油,乙酸乙二胺二钠,山梨酸,醋酸盐维他命E,羟苯丁酯,维他命A酯,鸢尾花根萃取,透明质酸钠,羟苯乙酯,羟苯丙酯,苦橙油,柠檬精油,芳樟醇
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MAIN OUTCOME MEASURES: The contents of monoamine neurotranmitters of norepinephrine, adrenalin, dopamine and 5-serotonin (5-HA) and its metabolites of DHPR, 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid in the striatum and marginal area of brain in rats were observed.
主要观察指标:大鼠纹状体和脑边缘区单胺类递质去甲肾上腺素、肾上腺素、多巴胺和5-羟色胺及其代谢产物3,4-二羟苯乙二醇、5-羟吲哚乙酸、高香草酸的含量。
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The dopamine release in vivo was monitored by fast cyclic voltammetry and the concentrations of DA and its metabolites dihydroxy-phenylacetic acid and homovanillic acid were determined by high performance liquid chromatography electrochemical detection in the process study. In addition, the effects of some traditional Chinese herbs and related marine drug on behavioral changes were also evaluated in order to provide some suggestive clue for rational drug design of anti-Parkinon's disease .
许多因素都参与PD的DA能神经元的死亡,所以,本研究在制备PD动物模型的基础上,应用国内率先引进的快速周期伏安法检测设备在体动态监测DA的释放,同时应用另一种电化学检测技术—高效液相色谱电化学检测法离体检测DA及其代谢产物二羟苯乙酸和高香草酸的含量,结合行为学测定及其它方法,研究了雌激素和铁在PD发病中的作用,以及一些药物,如吲哚醌、牛磺酸、铁离子螯合剂、胆囊收缩素(CCK-8)、乌鸡白凤丸有效成份、大豆异黄酮及海洋酸性寡糖HSH971,对DA能神经元的影响,从DA能神经递质角度对PD的发病机理提供进一步的实验依据,并为PD的预防和治疗提供新的干预措施。
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In the pretreatment group, Bak Foong Pill extracts were given for 14 days prior to MPTP. Immunostaining of tyrosine hydroxythase was used to observe the damage of dopamine neurons, and of Bax to detect the protein levels of Bax. High performance liquid chromatography-electrochemical detection was used to investigate the contents of DA and its metabolites dihydroxy-phenylacetic acid and homovanillic in the Str.
给予BFP预处理后,用酪氨酸羟化酶免疫组织化学法观察黑质神经元的变化;同时应用免疫组织化学法检测Bax蛋白表达;应用高效液相-电化学方法检测纹状体巴胺及其代谢产物二羟基苯乙酸和高香草酸的含量变化。
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Methods The effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 7-nitroindazole (7-NI) on nitric oxide synthase activity, levels of dopamine、3,4-dihydroxyphenylacetic acid、homovanillic acid, and TH-immunostained postive nerve fibres in the striatum of mice were determined by using colorimetic analysis, HPLC with electrochemical detection, and immunohistochemical analysis.
用比色分析、高效液相色谱电化学及免疫组化法检测1-甲基-4-苯基-四氢吡啶和7-硝基吲唑(7-NI)对C57BL小鼠纹状体一氧化氮合酶活性,多巴胺、二羟基苯乙酸、高香草酸水平和酪氨酸羟化酶免疫阳性神经纤维的影响。
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In the pretreatment group, Bak Foong Pill extracts were given for 14 daya prior to MPTP. Immunostaining of tyrosine hydroxythase was used to observe the damage of dopamine neurons, and of Bax to detect the protein levels of Bax. High performance liquid chromatography-electrochemical detection was used to investigate the contents of DA and its metabolites dihydroxy-phenylacetic acid and homovanillic in the Str.
给予BFP预处理后,用酪氨酸羟化酶免疫组织化学法观察黑质神经元的变化;同时应用免疫组织化学法检测Bax蛋白表达;应用高效液相-电化学方法检测纹状体多巴胺及其代谢产物二羟基苯乙酸和高香草酸的含量变化。
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Immunohistochemistry technology was used to evaluated tyrosine hydroxylase of DA synthesis. DA, 5-hydroxytryptophan(5-HT) and their respective metabolic products 3,4 -dihydroxyphenylacetic, homovanillic are also precisely quantified in this research by using high-pressure liquid chromatography with electrochemical detector. The main metabolism monoamine oxidase of DA was processed too. RESULTS:WD can increase the synthesis and the metabolism process of DA .
本文观察了温胆汤及其配伍对大鼠刻板行为的影响,采用了免疫组化技术对多巴胺的合成酶—酪氨酸羟化酶进行了含量测定,应用高效液相-电化学法测定了DA、5-羟色胺(5-HT)及代谢产物3,4—二羟基苯乙酸、高香草酸的含量,并测定了DA主要降解酶—单胺氧化酶。
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