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二羟基苯

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Water,c12-20 acid peg-8 ester,octyldodecanol,propylene glycol,coco-caprylate/caprate,cetearyl isononanoate,prunus amygdalus dulcisoil,biosaccharide gum-1,phenoxyethanol,ethylhexyl methoxycinnamate,potassium cetyl phosphate,simmondsia chinensisseed oil,carbomer,glyceryl polymethacrylate,malva sylvestrisextract,glyceryl stearate,cetearyl alcohol,cetyl palmitate,cocoglycerides,c12-13 alkyl lactate,methylparaben,sorbic acid,disodium edta,sodium hydroxide,tocopheryl acetate,benzophenone-3,iris germanica root extract,retinyl palmitate,butylparaben,peg-8,propylparaben,ethylparaben,sodium hyaluronate,chlorhexidine digluconate,tocopherol,ascorbyl palmitate,citric acid,ascorbic acid

水, c12-20 acid peg-8 ester,辛基十二烷醇,丙二醇,coco-caprylate/caprate,鲸蜡硬脂醇异壬酸酯,甜杏仁油,多醣物质,苯氧乙醇,4-甲氧基肉桂酸-2-乙基己基酯,十六烷基磷酸钾,西蒙得木籽油,卡波姆,甘油聚甲基丙烯酸酯,锦葵萃取,甘油硬脂酸,棕榈醇,十六烷基棕榈酸酯,椰油脂酸甘油酯类,c12-13烷醇乳酸酯,对羟基苯甲酸甲酯,山梨酸,乙二胺四乙酸二钠,氢氧化钠,维生素E醋酸酯,二苯甲酮-3,鸢尾花萃取,维他命A酯,对羟基苯甲酸丁酯,聚乙二醇-8,羟苯丙酯,羟苯乙酯,透明质酸钠,洗必泰葡萄糖酸盐,维生素E ,维生素C棕榈酸酯,柠檬酸,抗坏血酸

Water,c12-20 acid peg-8 ester,caprylic/capric triglyceride,proplylene glycol,ppg-15 stearyl ether,chondrus crispus,iris germanica(orris extract/cells),centaurea cyanus,macadamia ternifolia,buxus chinensis,triethanolamine,potassium cetyl phosphate,butyrospermum parkii,c12-13 alkyl lactate,carbomer,phenoxyethanol,methylparaben,imidazolidinyl urea,glyceryl hydroxystearin,tocopheryl acetate.retinyl palmitate,sodium hyaluronate,biosaccharide gum-1,propylparaben,disodium edta,ethylparaben,pentadecalactone,hydroxystearic acid,tetradecyloctadecanoic acid,tetradecyleicosanoic acid,hexadecyleicosanoic acid,butylparaben,isobutylparaben,chlorhexidine digluconate,tocopherol,lecithin,ascorbyl palmitate,glyceryl stearate,glyceryl oleate,BHT,citric acid.

水,C12-20 酸 PEG-8酯,辛酸/癸酸三酸甘油酯,丙二醇,PPG-15 硬脂基醚,卡拉胶萃取,德国鸢尾花提取物/细胞,矢车菊提取物,澳洲坚果油,荷荷巴油,三乙醇胺,十六烷基磷酸钾,牛油果,c12-13烷醇乳酸酯,卡波姆,苯氧乙醇,羟苯甲酯,尿素醛,甘油羟基硬脂酸酯,醋酸盐维他命E,维他命A酯,透明质酸钠,多醣物质,羟苯丙酯,乙酸乙二胺二钠,羟苯乙酯,环十五内酯,羟基硬脂酸,十四烷基十八烷酸,十四烷基二十烷酸,十六烷基二十烷酸,羟苯丁酯,对羟基苯甲酸异丁酯,洗必泰葡萄糖酸盐,维生素E,卵磷脂,抗坏血酸棕榈酸酯,甘油硬脂酸,甘油油酸酯,BHT,柠檬酸。水:几乎所有护肤品成分第一位都是水。辛酸/癸酸三酸甘油酯:润滑剂、扩散剂,棕榈油/椰子油衍生物

Water,decyloleate,propylene glycol,stearic acid,glyceryl stearate,peg-100 stearate,iris germanica(orris extract/cells),chamomilla recutita,arctium majus,prunus dulcis,ceteareth-3, Triethanolamine,phenoxyethanol,methylparaben,imidazolidinyl urea,carbomer,c12-13 alkyl lactate,disodium edta,propylparaben,glyceryl hydroxystearate,cetyl esters,ethylparaben,pentadecalactone,cera microcristallina,trihydroxystearin,butylparaben,hydroxystearic acid,isobutylparaben,chlorhexidine digluconate,tetradecyloctadecanoic acid,tetradecyleicosanoic acid,tocopherol,lecithin,ascorbyl palmitate,glyceryl oleate,citric acid

水,油酸癸酯,丙二醇,硬脂酸,甘油硬脂酸,聚乙二醇硬脂酸酯,鸢尾花提取物/活细胞,洋甘菊萃取,牛蒡提取物,甜杏仁油,鲸蜡硬脂醇醚,三乙醇胺,苯氧乙醇,羟苯甲酯,尿素醛,卡波姆,c12-13烷醇乳酸酯,乙酸乙二胺二钠,羟苯丙酯,甘油羟基硬脂酸酯,十六烷基酯,羟苯乙酯,环十五内酯,微晶蜡,三羟基硬脂精,羟苯丁酯,羟基硬脂酸,对羟基苯甲酸异丁酯,洗必泰葡萄糖酸盐,十四烷基十八烷酸,十四烷基二十烷酸,维生素E ,卵磷脂,抗坏血酸棕榈酸酯,甘油硬脂酸,柠檬酸水:几乎所有护肤品成分第一位都是水。油酸癸酯:滋润、柔肤剂,并常添加于多种化妆品中作为溶剂

Water,butylene glycol,cyclomethicone,VP/VA copolymer,glyceryl stearate,glycerin,ppg-15 stearyl ether,titanium dioxide,propylene glycol,cetyl alcohol,citrus aurantium dulcisfruit extract,saccharide isomerate,biosaccharide gum-1,ethoxydiglycol,peg-40 stearate,glycyrrhiza glabraroot extract,morus bombycis root extract,potassium cetyl phosphate,phenoxyethanol,c12-20 acid peg-8 ester,triethanolamine,prunus amygdalus dulcis oil,carbomer,caprylyl glycol,caffeine,disodium edta,methylparaben,chondrus crispus,butylparaben,iris germanica root extract,pentadecalactone,sodium polyacrylate,ethylparaben,sodium hyaluronate,peg-8,propylparaben,citric acid,chlorhexidine digluconate,tocopherol,ascorbyl palmitate,ascorbic acid

水,丁烯二醇,环甲硅脂,VP/VA共聚物,甘油基硬脂酸,甘油,ppg-15 stearyl ether,二氧化钛,丙二醇,十六烷基醇,橙子萃取物,天然异构寡糖, biosaccharde gum-1,乙基氧基乙二醇,聚乙二醇- 40硬脂酸,甘草根提取物,桑白皮根萃取,钾十六烷基磷酸盐,苯氧乙醇,c12-20 acid peg-8 ester,三乙醇胺,甜杏仁油,高分子胶,辛乙二醇,咖啡因,乙二胺四乙酸二钠,对羟基苯甲酸甲酯,卡拉胶,对羟基苯甲酸丁酯,鸢尾花根萃取, pentadecalactone ,聚丙烯酸钠,羟苯乙酯,透明质酸钠,聚乙二醇- 8,羟苯丙酯,柠檬酸,洗必泰葡萄糖酸盐,维生素E,维生素C棕榈酸酯,抗坏血酸

Water,c12-20 acid peg-8 ester,octyldodecanol,cetearyl isononanoate,butylene glycol,biosaccaride gum-1,peg-40 hydrogenated caster oil,ethylhexyl menthoxycinnamate,phenoxyethanol,potassium cetyl phosphate,macadamia ternifolia seed oil,dimethicone,carbomer,propylene glycol,glyceryl stearate,cocoglycerides,butyrospermum parkii,c12-13 alkyl lactate,methylparaben,benzophenone-3,pentadecalactone,sorbic acid,citrus aurantium dulcis oil,sodium hydroxyde,tocopheryl acetate,disodium edta,iris germanica root extract,retinyl palmitate,equisetum arvense extract,butylparaben,peg-8,propylparaben,ethylparaben,sodium hyaluronate,chlorhexidine digluconate,citrus aurantium amaraoil,tocopherol,ascorbyl palmitate,citric acid,ascorbic acid,limonene,linalool

水,c12-20 acid peg-8 ester,辛基十二烷醇,鲸蜡硬脂醇异壬酸酯,丁烯二醇,多醣物质,PEG-40氢化蓖麻油,4-甲氧基肉桂酸-2-乙基己基酯,苯氧乙醇,十六烷基磷酸钾,澳洲胡桃子油,地美司康,卡波姆,丙烯乙二醇,甘油硬脂酸,椰油脂酸甘油酯类,牛油果,c12-13烷醇乳酸酯,对羟基苯甲酸甲酯,二苯甲酮-3 ,环十五内酯,山梨酸,甜橙油,氢氧化钠,维生素E醋酸酯,乙二胺四乙酸二钠,鸢尾花萃取,维他命A酯,问荆萃取,对羟基苯甲酸丁酯,聚乙二醇- 8,羟苯丙酯,羟苯乙酯,透明质酸钠,洗必泰葡萄糖酸盐,苦橙油,维生素E ,维生素C棕榈酸酯,柠檬酸,抗坏血酸,柠檬精油,沉香醇水:几乎所有护肤品成分第一位都是水。辛基十二烷醇:界面活性剂、乳化剂、稠化剂,有一定刺激性

In this thesis,the AM1,MNDO,MINDO/3(mainly AM1)and INDO/S-CI semiempirical MO methods were used toinvestigate the excited-state intramolecular protontransfer reactions of salicylic acid derivatives—salicylic acid,methyl salicylate,salicylaldehyde,o-hydroxyaceto-phenone,salicylamide and 3-hydroxy-picolinamide (6 conformers and 2-3 anion species);2-(2'-hydroxy-5' methylphenyl) benzotriazole(4 conformers),2-(2' hydroxyphenyl) benzimidazole (3 conformers and 3anion species),Bis-2,5-(2-benzoxazolyl)hydroquinone(3 conformers),2-(2'-hydroxyphenyl)benzothiazole(2conformers) and 7-azaindole dimer (2 conformers).Theinvestigations were described as follows.Geometry optimization,relative stability andhydrogen bonding energy First,for sylicylic acid derivative molecules,the AM1,MNDO and MINDO/3 methods were used toinvestigate ground-state geometry optimization,energies,relative stabilities and hydrogen-bondingenergies on the five kinds of the molecules(designing 6 conformers and 2-3 anion species).Comparing with experimental data,the optimizedgeometry,the order of stability,the hydrogen-bonding energies and the distances between O-O in O-H..O hydrogen bonds by AM1 method were in agreementwith the experimental data,however,the C-C bondlengths optimized by MNDO and MINDO/3 were longer,C-O and O-H bond lengths were shorter;for C-N bondlengths,the results opitimized by MNDO method werethe same as those by AM1 method,nevertheless the C-Nbond lengths given by MINDO/3 method were muchshorter.For some sylicylic acid derivatives(e.g.methyl salicylate,salicylamide),the order ofstabilities on the conformers given by MNDO andMINDO/3 methods were not in agreement with theexisting conformers deduced by experimental methods,and the hydrogen bonding energies calculated by MNDO.and MINDO/3 methods were smaller.Second,the studyon the other systems found that the optimizedgeometry of the proton-transfered product with INDOmethod could not be obtained,only could theoptimized geometry of reactant be obtained,and thecalculated hydrogen bonding energies were greater.Many results of calculation indicated that the studyon the excited-state intramolecular proton transferreaction system using AM1 method was suitable andreliable.

本论文用AM1、MNDO、MINDO/3(主要是AM1)和INDO/S-CI半经验分子轨道方法对水杨酸衍生物系列——水杨酸、水杨酸甲酯、水杨醛、O-羟基乙酰苯酮、水杨酰胺和3-羟基吡啶酰胺(6种异构体和2-3种阴离子);2-(2'-羟基-5'-甲基苯基)苯并三〓唑(4种异构体);2-(2'-羟基苯基)苯并咪唑(3种异构体和3种阴离子);2,5-二间氮杂氧茚氢醌(3种异构体);2-(2'-羟基苯基)间〓杂硫茚(2种异构体)和7-〓吲哚二体(2种异构体)的激发态分子内质子转移反应在以下几个方面进行了较系统的理论研究:几何构型优化和相对稳定性及氢键能首先以水杨酸衍生物系列分子为例,用AM1、MNDO和MINDO/3方法考察了5种分子(每种分子设计6种异构体和2-3种阴离子)的基态几何构型优化,能量、相对稳定性和氢键能计算,通过和实验数据进行比较,AM1方法给出的优化几何构型、稳定性次序、氢键能和O—H。。。O氢键的0—0距离与实验数据吻合最好,MNDO和MINDO/3方法优化的C-C键长偏长,C-O键和O-H键长偏短;对于C-N键长,MNDO和AM1优化结果差别不大,而MINDO/3给出了过短的C-N键长,MNDO和MINDO/3方法给出的有些水杨酸衍生物分子(如水杨酸甲酯和水杨酰胺)异构体的稳定性次序和实验上推测的可存在异构体结果不一致,MNDO和MINDO/3方法给出的氢键能偏低,对其他体系的研究发现INDO方法常常不能得到质子转移产物的优化几何构型,只能得到反应物的优化构型,并且估算的氢键能偏高,大量的计算结果表明AM1方法对本论文研究的激发态分子内质子转移反应体系是适宜和可靠的。

Water,caprylic/capric triglyceride,mineral oil,butylene glycol,stearic acid,acetylated lanolin,glycerin,ethylhexyl methoxycinnamate,dimethicone,polyisoprene,triethanolamine,cyclopentasiloxane,butyl methoxydibenzoylmethane,titanium dioxide,persea gratissima oil unsaponifiables,sodium DNA,borago officinalis seed oil,oenothera biennis oil,simmondsia chinensisseed oil,hydrolyzed RNA,tocopheryl acetate,urea,hydrolyzed extensin,retinyl palmitate,sodium hyaluronate,helianthus annuusseed oil,tocopherol,ascorbyl palmitate,ascorbic acid,lanolin alcohol,c12-20 acid peg-8 ester,cyclotetrasiloxane,glyceryl stearate,dimethiconol,ceteareth-20,carbomer,magnesium aluminum silicate,propylene glycol,peg-8,silica,BHT,citric acid,phenoxyethanol,methylparaben,butylparaben,ethylparaben,isobutylparaben,propylparaben,chlorhexidine digluconate

水,辛酸/癸酸三酸甘油酯,矿物油,丁二醇,硬脂酸,乙醯化羊毛脂,甘油,4-甲氧基肉桂酸-2-乙基己基酯,地美司康,聚异戊烯,三乙醇胺,环戊硅氧烷,丁基甲氧基二苯甲醯基甲烷,二氧化钛,酪梨油,DNA 钠盐,琉璃苣種子植物油,月见草油,荷荷巴籽油,水解RNA,醋酸盐维他命E,尿素,水解伸展蛋白,维他命A酯,透明质酸钠,葵花籽油,维生素E,抗坏血酸棕榈酸酯,维生素C衍生物,羊毛脂醇,C12-20 酸 PEG-8酯,环四硅氧烷,甘油硬脂酸,聚二甲基硅氧烷醇,鲸蜡硬脂醇醚-20,卡波姆,硅酸镁铝,丙二醇,聚乙二醇-8,二氧化硅,二丁基羟基甲苯,柠檬酸,苯氧乙醇,羟苯甲酯,羟苯丁酯,羟苯乙酯,羟苯甲酸异丁酯,羟苯丙酯,洗必泰葡萄糖酸盐

To study the bioactive components from water soluble extract of the Chinese eaglewood, various column chromatography of Chinese eaglewood led to the isolation of ten compounds. Their structures were elucidated as 2,3-bis(3-hydroxyphenyl)- propan-1-ol (1), [(2R,3R)-3-(4-amino-3,5-dimethoxyphenyl)oxiran-2-yl]methanol (2), 8-chloro-4'- methoxy-5,6,7,3'-tetrahydroxy-2-(2-phenethyl)-5,6,7,8-tetrahydrochromone (3), 4'-methoxy-5,6,7,3'-tetrahydroxy-2--5,6,7,8-tetrahydrochromone (4), the isomer of 4 (5), 4'-methoxy-5,6,7,8-tetrahydroxy-2-(3'-hydroxyphenethyl)-5,6,7,8- tetrahydrochromenone (6), 4'-methoxyisoagarotetrol (7), 6-hydroxy-2-(2-hydroxy-2- phenethyl)-chromone (8), 6-hydroxy-2-(2-phenethyl)-chromone (9), 6-hydroxy-2-(4'- hydroxy-2-phenethyl)-chromone (10), and Guaiacylacetone (11) by means of spectral analysis and comparison with references.

为了进一步发现沉香中具有生理活性的化学成分,本文对国产沉香的水溶性成分进行了研究,从中分离得到11个化合物,通过红外、紫外、质谱、核磁共振(1H-NMR, 13C-NMR, COSY, HSQC, HMBC, ROESY)波谱解析,分别鉴定为:2,3-二(3-羟基苯基)-丙-1-醇(1),[(2R,3R)-3-(4-氨基-3,5-二甲氧苯基)-2-氧化烯基]甲醇(2),8-氯-4'-甲氧基-5,6,7,3'-四羟基-2-(2-苯乙基)-5,6,7,8-四氢色原酮(3),4'-甲氧基-5,6,7,3'-四羟基-2-(2-苯乙基)-5,6,7,8-四氢色原酮(4),化合物3的差向异构体(5),4'-甲氧基-5,6,7,8-四羟基-2-(3'-羟基-2-苯乙基)-5,6,7,8-四氢色原酮(6),4'-甲氧基异沉香四醇(7),6-羟基-2-(2-羟基-2-苯乙基)色原酮(8),6-羟基-2-(2-苯乙基)色原酮(9),6-羟基-2-(4'-羟基-2-苯乙基)色原酮(10)和Guaiacylacetone (11)。

The invention adopts halogen acetylized crosslinked polystyrene resin and hydroxybenzyl alcohol as the raw material, and the solid phase synthesis carrier with hydroxymethyl as the active group is synthesized through the joint catalysis of N, N-dimethyl formamide used as the reaction solvent, inorganic base and phase-transfer catalyst.

本发明采用卤乙酰化交联聚苯乙烯树脂和对羟基苯甲醇为原料,在以N,N-二甲基甲酰胺为反应溶剂、无机碱及相转移催化剂的共同催化下合成了一种以羟甲基为活性基团的固相合成载体。

In the case of BDD the mineralisation of the sodium dodecyl benzene sulfonate was achieved in all experimental conditions due to reaction with hydroxyl radicals electrogenerated on the diamond surface during electrolysis.

在这个案例的矿化的钠1 十二烷基苯酯所有实验条件下反应而羟基自由基在金刚石表面溶在意外发生。

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