二甲苯基

The pyrimidine lead compound is obtained via herbicidal activity screen. The optimization of lead compound leads to find the good pyrimidine benzylamine candidates with highly effective herbicidal activity. The novel herbicidal mechanism of pyrimidine benzylamine is put forward. N-(2-bromophenyl)-2-(4, 6-dimethoxypyrimidin-2-yloxy)benzylamine (103-1) has potential as a new selective post-emergent herbicide in oilseed rape.

通过系统的研究工作，发现了具有除草活性的嘧啶先导结构，经结构优化，筛选出具有高除草活性的嘧啶苄胺类优选结构，发现并提出了此类化合物的除草作用新机理，最终经田间试验证实了N-(2-溴苯基)-2-(4，6-二甲氧基-2-嘧啶氧基)苄胺(103-1)可作为超高效油菜田除草剂进行工业性的研究与开发。

A fluorescent boronic acid, dapoxylTM 3-sulfonamidophenylboronic acid was first used for the determination of glucose.

荧光染料(3-〔5-（4-二甲氨基苯基)-4，5-二氢唑-2-苯磺酰氨基〕苯硼酸被首次应用于体液中葡萄糖的直接测定。

These data were used to infer the molecular formula and the elemental compositions of all the fragmental ions through software interpretation and, by further applying fragmentation regularities of mass spectrometry, the majority of ions were fully assigned. A base peak at m/z 402 in the mass spectrum was found as the molecular ion. The fragments were created mainly from the fragmentations of the tetrahydrofuran rings and the hydroxyl group. The most fragment products contain the dimethoxy phenyl group.

利用这些数据通过软件导出了分子式和所有碎片离子的元素组成，由此进一步根据质谱裂解规律对石梓醇分子的电子轰击质谱的主要裂解碎片给出了完全的归属，质谱中发现基峰为分子离子峰(m/z402)，裂解碎片主要来自双骈四氢呋喃环的裂解和羟基引起的裂解，绝大部分裂解产物包含二甲氧基苯基基团。

In order to investigate the mechanism for this reac-tion, methyl α-bromoacetate or ethyl α-bromoacetate as starting material was added to the solution of phenyl selenoamide in ethanol in 1∶1 or 2∶1 molar ratio under the neutral condition at room temperature. The results indicated that the same product bis or bis diselenide was formed. Byproduct ethyl benzoate was also separated.

为了研究该反应机理，选择α-溴代乙酸甲酯或α-溴代乙酸乙酯在无催化剂、中性条件下，乙醇溶液中与苯基硒代酰胺室温下反应，投料比为1∶1和2∶1，结果也都生成了同一类产物二甲氧羰基甲基二硒醚或二乙氧羰基甲基二硒醚，同时还分离得到了相应的副产物苯甲酸乙酯。

In order to investigate the mechanism for this reaction, methyl α-bromoacetate or ethyl α-bromoacetate as starting material was added to the solution of phenyl selenoamide in ethanol in 1:1 or 2:1 molar ratio under the neutral condition at room temperature. The results indicated that the same product bis or bis diselenide was formed. Byproduct ethyl benzoate was also separated.

为了研究该反应机理，选择α-溴代乙酸甲酯或α-溴代乙酸乙酯在无催化剂、中性条件下，乙醇溶液中与苯基硒代酰胺室温下反应，投料比为1：1和2：1，结果也都生成了同一类产物二甲氧羰基甲基二硒醚或二乙氧羰基甲基二硒醚，同时还分离得到了相应的副产物苯甲酸乙酯。

The slices were divided into two groups. In group I, the slices were perfused with 5-HT(subscript 2A) receptor excitomotory-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane dissolved in modified Kreb's solution. In group Ⅱ, the slices were perfused with ketanserine specific antagonist of 5-HT(subscript 2A) receptor. The effects of DOI and ketanserine on RRDA were observed.

标本分2组：第1组使用含5-HT(下标 2A)受体特异激动剂2，5-二甲氧基－4-碘苯基丙烷的Kreb's液灌流脑片，观察其对RRDA的影响；第2组使用含5-HT(下标 2A)受体特异拮抗剂酮舍林的Kreb's液灌流脑片，观察其对RRDA的影响。

Simultaneously we prepared benzimidazolines with two methods by the of reduction benzimidazolium salts with NaBH_4 and Grignard addition with benzimidazolium salts. Thus we provided a new biomimic synthetic method for 13 kind of tetrahydroisoquinoline starting from carboxylic aicd and halid, gave a new idea of the synthesis for new drugs.It can make many kind ofβ-carboline alkaloids which have bioactivity to antibacterium, antivirus and antitumor to start from 1,2,3,4-tetrahydro -β-carboline.

本文以1，3-二甲基苯并咪唑碘盐和2-取代的1，3-二甲基苯并咪唑碘盐为原料，采用了NaBH_4还原和Grignard试剂加成两种方法，制备了13种1，3-二甲基苯并咪唑烷和2-取代的1，3-二甲基苯并咪唑烷作为四氢叶酸辅酶一碳单元转移新模型，在酸性条件下，以2-(3，4-二甲氧基苯基)乙胺作为接收一碳转移的亲核试剂，完成了13种重要的四氢异喹啉类化合物的新合成方法研究。

With headquarter in Shanghai, Kaikai Yuansheng Medicine is manufacturing and exporting the API裈rimebutine maleate and its intermediates with chemical name of Phenyl-2-Dimethyl Amino-2-Butanol as well as 150 kinds of medicinal products.

开开援生制药总部设于上海，主要生产和出口马来酸曲美布汀医药原料、中间体2-苯基-2-二甲氨基-丁醇及中西药品共150多个品种。

According to the results of the examination, the stronger the electron-withdrawing protective group of imines, the better the cis-selectivity of the reaction, 68% yield, trans:cis is 99:1 diastereoselectivity could be leaded by Ts-imines (4-methyl-N-methylene-benzenesulfonaides) with a substituent [2,4-(CH3O)2C6H3], Substrate scope investigation revealed that a wide variety of ketenes and imines could react smoothly to afford corresponding,β-lactams.

实验结果表明，亚胺的保护基团吸电子能力越强，越有利于顺式产物的生成。对甲苯磺酰基保护的取代基为2，4-二甲氧苯基的亚胺参与的该反应可得到68%的产率，反式：顺式=99：1的非对映选择性。底物拓展过程中发现Staudinger反应适用于多种不同的亚胺与烯酮。

It seems likely that Kraft will return with a better offer.

看起来卡夫要重新考虑一个更好的出价了。

But he'd rather burn off my feelers and watch me squirm.

可他却放任那个家伙对我为所欲为！