二甲基吡啶

In this thesis, a convenient and efficient synthesis of highly functionalizeddihydropyrido[2,3-d]pyrimidines via a double [5 + 1] annulation strategy startingfrom easily available α-alkenoyl-α-carbamoyl ketene--acetals 1 and cheapreagents (NH4OAc, DMF, and POCl3) has been developed.

本论文探索了一种简便有效的合成高度官能化的二氢吡啶并[2，3-d]嘧啶的方法，此方法由易得的α-乙酰基-α-氨基乙酰基二硫缩烯酮1和便宜的试剂(醋酸铵，二甲基甲酰胺和三氯氧磷)通过两步[5 + 1]加成而实现。

Molecularly imprinted polymers of sulfamethazine(SM 2 ) were prepared with silica gel as a sacrificial material, methacrylic acid and 4 vinylpyridine(4 Vp) as functional monomers, glycol dimethacrylate as crosslinker. The polymer properties were investigated by static adsorption experiments. Scatchard analysis shows that the adsorption ability of MAA MIP is superior to that of 4 Vp MIP. The dissociation constant of MAA MIP is 9 59×10 -4 mol/L. The value of apparent binding a...

以磺胺二甲嘧啶为模板分子，分别用甲基丙烯酸和4乙烯基吡啶为功能单体，二甲基丙烯酸乙二醇酯为交联剂，采用牺牲硅胶法合成了磺胺分子印迹聚合物，通过静态吸附实验，系统研究了不同单体对聚合物识别性能的影响；Scatchard分析表明，以甲基丙烯酸为单体的聚合物具有较高的吸附能力，其离解常数Kd为959×10-4mol/L，最大表观结合位点数Qmax为3070μmol/g。

Three methods are used to prepare molecular imprinted polymers,which include conventional bulk technique or polymerization with ultraviolet initiated in low temperature and polymerization with silica-gel as sacrificial materials. In the polymerization procedure , Sulfamethazine(SM2)and Sulfisoxazole were used as target template molecules, methacrylic acid and 4-vinylpyridine(4-VP) and acrylamide were selected as functional monomers, ethylene glycol dimethacrylate as crosslinker, azobisisobutyronitrile was used as initator.

主要工作如下：首先，以磺胺异噁唑和磺胺二甲嘧啶为模板，分别以4-乙烯基吡啶，甲基丙烯酸，丙烯酰胺为功能单体，以二甲基丙烯酸乙二醇酯为交联剂，偶氮二异丁腈为引发剂，采用了传统方法(60℃恒温水浴)、牺牲硅胶法及低温紫外光聚合法等三种方法合成了一系列的磺胺类药物印迹聚合物。

Reactions of 2,6-pyridinedicarboxylic acid or 2,6-dibromomethyl pyridine with 5-(4-hydroxyphenyl)-10,15,20-triphenyl porphyrin, 5-(4-aminophenyl)-10,15,20 triphenyl porphyrin gave three novel bridged diporphyrins 3-5, respectively.

通过将2，6-吡啶二羧酸或2，6-二溴甲基吡啶分别与5-(4-羟基苯基)-10，15，20-三苯基卟啉(1)和5-(4-氨基苯基)-10，15，20-三苯基卟啉(2)反应，合成了3种新型的双卟啉化合物3~5。

It was discovered that proteases, lipases and abzymes can be used for the regioselective acylation of sucrose.

酶催化合成蔗糖酯通常在N，N-二甲基甲酰胺，二甲基亚砜和吡啶等有毒溶剂中进行。

Two novel A-it-A' type benzothiazole-based derivatives with benzothiazolyl, phenyl-acetyl or pyridine cation groups as π electron acceptor, diethenylphenyl as π conjugated bridge: 4-(2-benzothiazolyl) ethenylchalcone (1) and 4-{4-[2-(benzothiazole-2-yl) ethenyl] styryl}-N-methylpyridinium iodide (2) were synthesized.

以苯并噻唑、苯乙酰基和吡啶阳离子为电子受体，二乙烯基苯为共扼桥，合成了两个新的A-π-A'型苯并噻唑衍生物：4-（2-苯并噻唑）－乙烯基查尔酮(1)和4-｛4-［2-乙烯基］苯乙烯基｝－N-甲基吡啶碘盐(2)。

Two novel A-π-A′ type benzothiazole-based derivatives with benzothiazolyl,phenyl-acetyl or pyridine cation groups as π electron acceptor,diethenylphenyl as π conjugated bridge: 4-(2-benzothiazolyl)ethenylchalcone(1) and 4-{4-[2-(benzothiazole-2-yl)ethenyl]styryl}-N-methylpyridinium iodide(2) were synthesized.

以苯并噻唑、苯乙酰基和吡啶阳离子为电子受体，二乙烯基苯为共轭桥，合成了两个新的A-π-A′型苯并噻唑衍生物：4-(2-苯并噻唑)-乙烯基查尔酮(1)和4-{4-[2-乙烯基]苯乙烯基}-N-甲基吡啶碘盐(2)。

Chlorpyrifos mehtyl with different dosages of 3,5,10 mg/kg compared with malathion 15 mg/kg in grain silo,each contented 40 thousand kilograms of rice was studied.To be sprayed by machine when loading to silo and to be observed two years through all experiment,the effective control to sitophilus zeamais of chlorpyrifos mehtyl 5 mg/kg can be protected more than six months,and 10 mg/kg over one year.

报道了甲基毒死碑(化学名称为二甲基O-3，5，6-三氯-2-吡啶基硫逐磷酸酯)3、5、10 mg/kg不同剂量，以防虫磷15 mg/kg作比较，在立筒库星仓内，每筒40000 kg稻谷，机械喷雾法处理，储藏二年，经生物测定对玉米象药效，甲基毒死蜱5 mg/kg可达半年以上，10 mg/kg可达一年以上防护期。

In chapter four, molecular imprinting polymers against amino acid derivatives utilizing 2-VP+AM as combined functional monomer and trimethylolpropane trimethacrylate as tribasic cross-linker were prepared and result was compared with those with the same amino acid derivative as the imprinted molecules utilizing ethyleneglycol dimethacrylate as dibasic cross-linker. It was found that cross-link intensity of the molecular imprinting polymer is higher when TRIM was utilized and baseline separation for the imprinted molecule could be achieved. When TRIM was utilized as cross-linker more molecule is imprinted during the polymerization.

第四章采用2-乙烯基吡啶+丙烯酰胺复合功能单体，考察了三元交联剂三甲氧基丙烷三甲基丙烯酸酯烙印氨基酸衍生物的情况，并与二元交联剂乙二醇二甲基丙烯酸酯烙印相同氨基酸衍生物的情况进行了对比，发现三甲氧基丙烷三甲基丙烯酸酯交联剂在较小的用量下就可使分子烙印聚合物达到足够的交联度，实现烙印分子的基线分离。

The phosphorus oxychloride or phosphorus tribromide N, N-dimethylformamide mix and react to form the Vilsmeier reagent used in the reaction. The newly prepared Vilsmeier reagent is added into the reaction bottle provided with the return condenser and the blender; a reaction raw material N, N-dimethylformamide solution expressed in the reaction formula is added into the system; the temperature is risen; the corresponding multi substituting pyridine-2 (1 H)-ketone compound can be made after the column chromatography of the silica gel; the production rate is between 60 and 95 percent according to different reactions.

由三氯氧磷或三溴化磷N，N-二甲基甲酰胺混合获得反应中所用Vilsmeier试剂；将新配制的Vilsmeier试剂加入装有回流冷凝管、搅拌器的反应瓶中，向体系中加入反应通式中表示的一种反应原料的N，N-二甲基甲酰胺溶液，升温，经硅胶柱层析分离得相应的多取代吡啶-2(1H)-酮类化合物，产率视不同反应在60~95％之间。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。