二甲双胍

Objective: To study the effects of metformin on inflammation factors and blood lipids in patients of polycystic ovary syndrome.

目的：探讨二甲双胍对PCOS患者慢性炎症因子及血脂的影响。

The dimethyldiguanide combined with the chinese medicinal of fortify the spleen and resolve phlegm can improve serumal CRP and IL-6 better.

二甲双胍加用健脾化痰清热方药更能降低血清中的CRP和IL-6水平。

Objective To evaluate the effects of cyproterone acetate associated with metformin in patients with polycystic ovary syndrome unsensitive to CC.

目的 评估达英－35联合二甲双胍对克罗米芬不敏感型多囊卵巢综合征不孕患者的治疗作用。

And we saw there was when we look at the rosiglitozone group, it appeared to have superior to metformin and uria group with regard to myocardial infarction and stroke.

RECORD试验显示，罗格列酮减少心肌梗死和卒中优于二甲双胍和磺脲类。

I like pioglitazone based on the PROactive data, it is a study with some flaws but in the land of the blind the one eyed man is king so in the posse of outcome evidence we have for diabetes treatment PROactive stands with metformin as evidence based.

基于PROactive的数据我也喜欢吡格列酮这个药物，虽然这项研究有一些瑕疵，但是盲人之国，独眼称雄。在这些结果中对于糖尿病治疗PROactive赞成使用二甲双胍。

The objective of the present study was to determine how metformin activates AMPK in endothelial cells.

本研究目的旨在明确在内皮细胞中二甲双胍如何激活AMPK。

Methods and materials A549 cells were collected and lysed for total protein after treated with metformin (5 mM) for 0, 15, 30 and 60 minutes. Western blot analysis was performed to detect the expressions of pan- and pho- AMPK, JNK and p38 proteins. Cleaved Caspase-3, 8, 9 proteins were also detected.

以5mmol/L的二甲双胍对A549细胞进行体外干预，在干预的第0、15、30和60min时，分别抽提细胞总蛋白，以Western blot技术检测细胞内AMPK、JNK、p38 MAPK的总蛋白和磷酸化蛋白的表达；在干预后第0、12、24和48h，检测剪切后的Caspase-3、8、9活性蛋白的表达水平。

Begin with metformin unless evidence or risk of renal impairment, titrating the dose over early weeks to minimize discontinuation due to gastro-intestinal intolerance.

如果没有肾脏受损或有受损危险的情况下，起始应用二甲双胍治疗。在最初的几周调整剂量，将由于胃肠道不适引起的停药减小到最少。

Objective: To observe the effects of metformin plus clomiphene in the treatment of patients with polycystic ovary syndrome.

目的：观察二甲双胍联合克罗米酚治疗多囊卵巢综合征合并不孕患者的疗效。方法：选择40例PCOS患者随机分成试验组和对照组各20例。

aim: to observe the treatment effect of metforminon clomiphene resistant infertile patients with polycystic ovary syndrome.

目的：探讨二甲双胍治疗多囊卵巢综合征不孕患者克罗米酚抵抗的效果。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。