二中心的

Nowadays, in the low electron dose condition, the information about 3-4〓 can be recorded on the cryoEM micrograph, and the high-resolution reconstruction using the cryoEM has reached 6. 5-8〓 levels. The reconstruction can reveal the protein α helical and recognise β fold secondary structure. Secondly, it is due to the development in 3D reconstruction method, which can be more efficient to determine the orientation and center parameters. The last but not least, it is also owning to the rapid development in computer science and information technology. Such as, some computational task, which previously must be executed by using super-computer, now can be carried out by personal computer, and at the same time, the network speed and band width of data bus and input/output equipment have increased several times. In addition, the improvement of the high quality graphic displaying is available. All these provide strong support for cryoEM high-resolution reconstruction study.

目前，在低电子剂量的情况下，冷冻电镜照片可以记录到3-4 〓的信息，使用冷冻电子显微镜进行高分辨三维重构工作，已经获得6.5-8〓高分辨率水平的结果，可以分辨出蛋白质的α螺旋、识别出蛋白质的β折叠等蛋白质二级结构；其次是，三维重构算法效能的不断提高，使得对二十面体取向和中心参数计算的可靠性大大提高；再次是，由于计算机和信息技术迅猛发展，例如，以往需要使用大型计算机的计算任务已经可以被一般的个人电脑完成，网络速度、数据总线和硬盘等I／O设备的带宽成倍增长，以及图像显示能力的提高都为冷冻电子显微镜高分辨三维重构技术提供了强有力的支持。

The relations of electrophoresis velocity, electroosmosis velocity and electric dispersion velocity are also investigated with these expressions. The results show that this new model offers a better explanation for peak compression effect on the migration behaviour of charged solute in CEC. The retention time will be shorter by peak compression effect, which is similar to a solvent gradients process. The peak compression effect is not steady, and doesn't appear until the conditions are fitted in some special situation.

基于弛豫理论所建立的基本模型，在考虑溶质在两相中皆有可能发生正、反向迁移的情况下，得到了流出曲线一阶原点矩和二阶中心矩的理论表达式，并通过对溶质在两相中电扩散速率与电泳速率、电渗流速率关系的分析结果证实：溶质在固定相表面的电扩散行为可以使其保留变弱，出峰加快；而这种电扩散导致的超常柱效峰的出现具有不稳定性，只有在多方面因素综合影响匹配的情况下才可能出现。

The mathematical models of the delay of the GPS signal in the circumstance are put forward respectively. The computation of orbital arc of the two satellite constellations is based on two body problem and perturbations models. An algorithm based on the IRI model and thin layer model is used to simulate the ionospheric delay of the GPS signal. The error models of observation, multipath, relativity and antenna phase center bias are also researched. Under the consideration of the autocorrelation of the electronical measurements, the autoregressive model of time series is introduced into the noise models.

在信号仿真中，研究了利用二体运动和摄动法计算LEO卫星至GPS卫星星座的几何距离的问题；在信号的误差模型中，研究了电离层时延的IRI2001模型和单层投影模型；讨论了观测误差、多径效应、相对论效应和天线相位中心偏移的误差模型；结合电子测量噪声的具有自相关特性的经验，研究了观测误差的AR模型；结合实测数据分析，讨论了接收机钟差和卫星钟差的误差建模问题。

The main works include five parts:(1) A modified K-means algorithm for optimizing the RBPNNs' structures was proposed;(2) The RBPNNs' structure optimization method based on the orthogonal least square algorithm was proposed that can greatly reduce the computation expense for the structure optimization;(3) Using the GA to perform the whole structure optimization of the RBPNNs was proposed in this thesis, which include simultaneous optimization of the hidden centers and the corresponding controlling parameters of the kernel functions.

主要工作体现在如下三个方面：(1)提出一种改进的 K-Means 算法；(2)提出了基于递推正交最小二乘算法的结构优化算法来训练径向基概率神经网络，从而大大减小了用于结构优化的计算开销；(3)提出使用遗传算法来实现径向基概率神经网络的全结构优化，即隐中心矢量和核函数控制参数同时优化，通过新设计的编码方式、新构造的适应度函数，充分发挥了 GA 的全局搜索性能，使得所优化的径向基概率神经网络的结构趋于最简。

In east " culture of a person adept in martial arts and given to chivalrous conduct " below the influence, the game that Oriental develops is met more encourage individual hero creed, player leading role is the center of the world, the existence of all underling is to make the bedding that the player comes on the stage only; And be in " chivalric culture " the Hesperian that grows in atmosphere, meet more encourage group cooperation, everything in game world all around " fair " 2 words, to the player, all be such to NPC, consequently very few conference appears " preterhuman type " play protagonist.

在东方"侠文化"的影响下，东方人开发的游戏会更鼓励个人英雄主义，玩家主角就是世界的中心，一切喽罗的存在都只是为了作玩家出场的铺垫；而在"骑士文化"氛围中成长的西方人，则会更提倡团队合作，游戏世界中的一切皆围绕"公平"二字，对玩家，对NPC皆是如此，因而很少会出现"超人式"的游戏主角。

Hierarchical linear modeling is the most frequently used technique for analyzing multilevel data. In this paper, the twelve key issues in multilevel research and/or using HLM software were reviewed, and provided their exact meanings and feasible solutions. The 12 key issues included intraclass correlation coefficient, sample sizes, formation of organizational constructs, centering problems, fixed effect and random effect, estimation methods, goodness of fit index, explained variation, multicollinearity, robust standard error, level one variance equation, and empirical Bayes estimates.

本文针对阶层线性模式在多层次研究上有关於技术、测量与方法论所遭遇的问题，进行文献整理并讨论其实务意涵，并依据使用时机、抽样议题、资料汇总、分析方法、与模式评估与估算等五方面整理出十二项重要议题与解决之道，包括：组内相关系数的意义与判断准则、多层次研究各层的样本数问题、变数聚合成组织层次问题、中心化的意义、固定效果与随机效果的设定、估计法的选择、适配度的比较、解释变异量的计算、多元共线性的分析、强韧性标准误、第一层误差项变异数与实证贝氏估计值的运用。

Twenty-odd years in the development process of the electronic components in our procurement, sales and service on the accumulated wealth of experience, and many internationally renowned supplier of electronic components to establish and maintain a good relationship, I Division has its own logistics Center, and established a global presence on four continents of the procurement and distribution network can provide our customers with 24 hours non-stop, global spot market within the scope of the emergency procurement services.

在二十余年的发展过程中，我司在电子元件采购、销售和服务上积累了丰富的经验，并且和很多国际知名的电子元件供应商建立和保持了良好的关系，我司拥有自己的物流中心，并且建立了遍布全球四大洲的采购和销售网络，可以为我们的客户提供24小时不间断的、全球现货市场范围内的紧急采购服务。

Part 2. Measurement of macular light sensitivity and FM 100-hue test in normal prese- nium and geratic people. The macular light sensitivity 、macular foveal light sensitivi- ty in 64 (82 eyes) and hue discrimination in 75 (100 eyes) normal presenium and geratic people were examined with macular threshold (white、red、blue and green color light) program of the Humphreh Field Analyzer and FM 100-hue test respectivity. The re- sults showed that the light sensitivity in four color light threshold was all declined with age. The mean error score square of each spectral region and whole spectral was increased with age, the loss of light sensitivity and hue discrmination was a linear correlated with age. The light sensitivity of the different field was compared, except blue color light threshold, the light sensitivity was decreased with the increasing of the eccentricity, white and red color light threshold in the inferior field showed lower sensitivity than that in the superior field.

二、老年前期及老年期正常人的黄斑阈值及FM100-色调试验检测采用Humphrey视野分析仪黄斑阈值程序和FM100-色调试验仪分别对82例（82眼）和75例（100眼）老年前期及老年期正常人进行了黄斑光敏度、黄斑中心凹光敏度及色调分辨力的测定，结果显示四种色光阈值的光敏度均随年龄增加而降低，FM100-色调试验各个色区及全色区错误记分方根随年龄增加而增高，光敏度及色调分辨力的降低与年龄呈线性相关；不同视野的光敏度比较，除蓝色光阈值外，光敏度均随视野偏心度的增加而减少，视野的上半部光敏度较下半部低；视野的鼻侧与颞侧及各象限的光敏度无显著差异。

The granitic enclaves in the central-facies porphyroblastic lava are subvolcanic rocks with forming age of 134.2±1.9Ma. There is another intrusion of subvolcanic rhyodacitic porphyry with age of 136.0±2.6Ma, in the contact zone of the two volcanic cycles in the western part of the Xiangshan complex. The U-Pb ages of the sub-quartz-monzonite porphyry and lamprophyre are 129.5±2.0Ma and 125.1±3.1Ma, respectively. This suggests that the extension in the Xiangshan region, began in K〓, was week, and earlier than that in the coastal region of Zhejiang and Fujian provinces. Extension in K〓 in Xiangshan and neighboring regions was much stronger, forming NE striking large red-downfaulted-basins.

相山中心相碎斑熔岩中的花岗质包体属次火山岩，其成岩年龄为134.2±1.9Ma，在相山西部两火山旋回的界面之间，存在另一类次火山岩的侵位，其成岩年龄为136.0±2.6Ma，岩性为次流纹英安斑岩；次石英二长斑岩及煌斑岩的成岩年龄分别为129.5±2.0Ma及125.1±3.1Ma，说明相山地区的伸展、裂解作用明显早于浙、闽沿海，在K〓就开始了，但规模并不是很大；而K〓时期的拉张作用在相山及其邻区表现的更为强烈，形成了大面积的呈北东向展布的红色断陷盆地。

By the study of the relationship between vegetation and spatial characteristics of UHI, the mainly spatial characteristics of UHI has been analyzed and it was:(1) The terrain of the suburbs is higher than the urban region, the gradient of the terrain height is small, and this geomorphological featrue is conducive to assemble of the heat, the UHI phenomenon of Changsha is obvious especially in the summer night;(2) The UHI distribution is similar to the outline of the urban construction. The LST of urban is 3-5℃ higher than the flat low areas close around the city, and 6-8℃ higher than further areas. The region which has the most obvious UHI phenomenon is the region surrounded by the second city ring road, and the UHI phenomenon gradually weakened from the city centre to suburb;(3) The impact of geomorphological character to UHI is notable, the relationship between vegetation index and UHI is Anti-related, it was indicated that the improvement of the vegetational status is very important to the elimination of UHI phenomenon, the implementation of the urban green land planning can reduce UHI effect.

通过分析长沙城市地区的土地覆盖、植被绿地状况与热岛空间分布状况的关系，揭示出研究区域UHI主要特征为：(1)从研究区域地表覆盖图发现，长沙市城区四周均有相对地势较高的山地，但地形梯度不大，接近四面环山的地貌特征，容易造成城区的热量聚集，有利于城市热岛效应的形成，使得长沙城区存在明显的热岛分布；(2)UHI分布与城市结构的轮廓相一致，长沙城区与地势相对平坦的近郊区的地表温度差异为3~5℃，与地势较高的周边远郊区的地表温度差异为6~8℃，长沙城区热岛效应与城市规划呈对应关系，热岛效应最显著的区域为二环线内，并从中心沿三环逐渐向郊区减弱；(3)地表覆盖类型对UHI的效应明显，长沙地区植被绿地状况与UHI呈现明显反相关分布，揭示出植被绿地对降低UHI具有重要的作用，大范围的绿地建设能有效降低UHI。

What would he tell Judith and the children?

他将怎样告诉朱迪丝和孩子们呢？

I this is at that time, the opinion with peacockish true girl is full of in a heart.

这就是当时的我，一个心中布满虚荣的女孩子真实的想法。