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The most common alpha hydroxyacids used for treatment of these problems are lactic acid and glycolic acid.

最通常的阿尔发作为这些问题的治疗的 hydroxyacids 是乳酸和 glycolic 酸。

MAIN OUTCOME MEASURES:①degradation rates of PLGA with different ratios of lactic acid and glycolic acid.

主要观察指标:①不同质量比聚乳酸-乙醇酸的降解速率。

A direct copolymerisation process was used to prepare lactic acid and glycolic acid copolymer.

采用直接法熔融缩聚制备了L 乳酸和乙醇酸共聚物PLGA ,并用锥板流变仪对PLGA的流变性能进行测试。

BACKGROUND: Poly-lactic glycolic acid is a good material for cell scaffold, but its poor cellular affinity and mechanical strength limit its application.

背景:聚乳酸-羟基乙酸是一种较好的细胞支架材料,但细胞亲和性较差、机械强度不够等缺点又限制了它的应用。

objective to optimize the formulation of methimazole loaded polylactic co glycolic acid microspheres.

目的 优化甲巯咪唑聚乳酸羟基乙酸共聚物微球的处方工艺。

OBJECTIVE: To investigate the biocompatibility of poly (DL-lactide-coglycolide). Copolymer ratio of lactide: glycolide was 85:15 or 50:50and evaluate its effect on nerve guidance.

目的:对共聚比为(85:15)及(50:50)的聚乳酸-聚羟基乙酸共聚物材料的生物相容性及神经再生诱导作用进行对比观测。

Because, until now, we only knew how to make these biodegradable polymers using two monomers (the basic components of polymers), lactide and glycolide. It is rather like making a bead necklace when only green and red beads are aailable.

因为,直到现在,我们只知道如何利用这些生物可降解聚合物使用良种单层膜,脱水乳酸和乙交酯,它就像党只有绿色和红色珍珠时也可以制成项链。

Firstly, D,L-lactide was synthesized from D,L-lactic acid with zinc powder as catalyst,and glycolide from glycolic acid using Sb2O3 as catalyst.

首先以乳酸为原料,锌粉为催化剂合成了丙交酯;以乙醇酸为原料,三氧化二锑为催化剂合成了乙交酯。

The pegylated polylactide-poly glycolide nanoparticle, whose surface was co-modified withmaleimide-polyethylene glycol and methoxy-polyethylene glycol, was made by double-emulsion and solvent evaporation method andcovalently conjugated with thiolated lactoferrin via its maleimide functionalgroup.

第一章首先由复乳/溶媒蒸发法制备马来酰亚胺—聚乙二醇(Maleimide-PEG,MAL-PEG)和甲氧基聚乙二醇表面共修饰的聚乳酸-聚羟基乙酸纳米粒,然后通过其表面MAL-PEG与巯基化Lf共价连接而制备Lf-NP_。

When 2.0 g/L of malate was added to the fermentation medium, the metabolic flux of byproducts L-Ala and lactic acid decreased by 22.1% and 16.5%. At the same time, the metabolic channeled to EMP and glyoxyl circle decreased by 2.26% and 9.09%. However, the metabolic flux channeled to HMP increased by 2.26%.The metabolic flux channeled to the L-glutamic acid synthesis pathway increased from 73.59% to 79.92%.

在L-谷氨酸发酵中、后期添加2.0 g/L苹果酸后,合成副产物L-丙氨酸和乳酸的代谢流量明显减少,分别降低了22.1%和16.5%,EMP途径和乙醛酸循环的代谢流分别减少了2.26%和9.09%,HMP途径的代谢流增加了2.26%,而L-谷氨酸生物合成的代谢流从73.59%增长至79.92%,较未添加前提高了6.33%。

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