乳腺癌

OBJECTIVE The hereditary breast and orarian cancer susceptibility gene(BRCA1) is known as a kind of anti-oncogene.

目的 遗传性乳腺癌和卵巢癌易感基因(hereditary breast and orarian cancer susceptibility gene， BRCA1)是一种抑癌基因。

Results Osseous metastasis was found in 22 cases out of the 107 cases with the positive rate of 20.6%: osseous metastasis occurred in 4 cases with no osteodynia, single metastasis in 9 cases and multi-metastasis in 13 cases; the location of osseous metastasis ranged as follows: 61 metastasis in thoracic cage, 41 in pelvis, 39 in vertebral column, 8 in four limbs and 4 in skull; along with the prolongation of the follow-up, the positive rate of osseous metastasis increased.

结果 107例中发现骨转移22例，阳性率20.6%。其中无骨痛患者发生骨转移4例，单发转移9例，多发转移13例。发现骨转移灶的部位依次为胸廓(61处)、骨盆(41处)、脊柱(39处)、四肢(8处)及头颅(4处)。随乳腺癌术后回访年限的增加，骨转移阳性率增加。

As one of the important medicated factor of osteoclast activity, PTHrP can induce the differentiation and mature of osteoclast and play an important role during the genesis and development of osteolytic bone metastasis of breast cancer.

PTHrP作为重要的破骨细胞活性介导因子之一，诱导破骨细胞分化和成熟，在乳腺癌溶骨性骨转移的发生、发展中起着重要作用。

This radiograph demonstrates osteolytic metastases in the pelvis in a patient with metastatic breast carcinoma.

乳腺癌病人X线片显示转移性病变，盆部的转移性肿瘤破坏溶解骨质，为溶骨性转移性骨肿瘤。

This chest radiograph demonstrates osteolytic metastases in a patient with metastatic breast carcinoma.

胸部X线显示，乳腺癌转移病人，胸部骨质溶解破坏。

Approximately 25% to 30% of breast cancer tumors overexpress the oncogene HER2/neu.

大约在25%到30%的乳腺癌中存在癌基因HER2/neu的过度表达。

Accumulated studies have found that the tumor cells and tumor-associated macrophages in tumor tissues such as ovarian cancer, lung cancer, breast cancer, renal cell carcinoma and adenoid cystic carcinoma overexpress B7-H4 molecules.

越来越多的研究发现，在肿瘤组织如卵巢癌、肺癌、乳腺癌、肾癌和腺样囊性癌等的肿瘤细胞以及肿瘤相关巨噬细胞中异常高表达B7-H4分子。

In part Ⅲ of this ariticle,The authors report some other neoplasms and precancerous changes, and they are adenoma of stomach, hemangiofibroma of ovary,carcinoma of Fallopian tube, osteo-petrosis,cholangiocarcinoma, polyps, leukoplakia,atypical hyperplasia, papillar...

这些肿瘤是鼻咽癌、副鼻窦癌、鼻腔癌、食管癌、卵巢癌，淋巴细胞性白血病、白色肉瘸、淋巴肉瘤，外阴癌、纤维肉瘤、原发性肝癌、小肠癌、结肠癌、乳腺癌，圆形细胞肉瘤、纤维瘤、脂肪瘤、马立克氏病、肾癌、畸胎瘤、膀胱乳头状瘤和口腔癌。

L1 was highly expressed in parotidean cystadenocarcinoma, pancreatic cancer and breast cancer examined.

病理分布提示它在腮腺囊腺癌、胰腺癌及乳腺癌中都有高表达。

People had been using it to treat the carcinoma of thyroid gland, lymphoma, parotidean carcinoma, tonsillar cancer, nasopharyngeal carcinoma, breast cancer, cervical cancer, liver cancer etc so long .

有关其抗肿瘤作用有较多的报道，如应用夏枯草治疗甲状腺癌、淋巴肉瘤、腮腺癌、扁桃腺癌、鼻咽癌、乳腺癌、宫颈癌、肝癌等由来己久。

We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称；三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起，称之为挽歌体诗人或者史诗诗人，他们被称为诗人，似乎只是因为遵守格律写作，而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。