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乳腺癌

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As a breast reduction is not vital to your health, it is known as cosmetic surgery.

作为乳腺癌减少并非是必不可少的,以您的健康,这是被称为整容手术。

Application of COX model for evaluation of the prognostic factors in patients with breast cancer.

COX 模型在影响乳腺癌术后预后因素分析中的应用。

She inhaled to heave her wobbling breast coyly.

她吸入,以鼓她摇晃乳腺癌coyly 。

For example, mutation carriers diagnosed initially in their early to mid 30s had a 31 percent cumulative probability of developing contralateral breast cancer within 10 years as compared to a 7 percent probability among non-carriers.

例如,初步诊断为突变携带者在30年代初期至中期有百分之三十的发展在10年内对侧乳腺癌的累积概率比较,在非运营商的概率为百分之七。

Objective:To study the curative effect of recurrent or metastatic breast cancer.

目的:探讨复发转移性乳腺癌的治疗效果。

In women over 30, cystic disease of the breast and carcinoma of the breast must be considered .

在30岁以上的妇女,囊性病变的乳腺癌和肠癌的乳房,必须予以考虑。

OBJECTIVE: To examine the performance of liquid-based cytology in breast cytology to confirm the diagnosis of carcinoma.

目的:检验应用液基细胞学在处理乳腺细胞诊断乳腺癌中的作用。

The results prove that CNHK500 has highly proliferation selectivity and potent cytolysis effect on breast cancer in vitro.

在感染CNHK500的端粒酶阴性的正常成纤维细胞株中未检测到E1A基因表达,在端粒酶阳性的感染CNHK500的乳腺癌细胞株中能够检测到E1A基因的表达;CNHK500可以选择性地在缺氧条件下表达E1B。

Methods: The telomerase activity in breast cancer cells and MRC-5 cell line were detected semi-quantitively by TRAP-ELISA assay. Virus proliferation as- say and cell viability assay were used to evaluate the proliferation and cytolysis selectivity of CNHK300, and the results were compared with those of wtAd5. The breast cancer cells were treated with CNHK300 combining paclitaxel to evaluate the killing effect of the combined regimen.

用TRAP-ELISA方法检测乳腺癌细胞株(MDA-MB-453、SK-BR-3)和正常成纤维细胞株MRC-5的端粒酶活性;进行病毒增殖实验和细胞生长抑制实验,并与野生型腺病毒wtAd5进行对比,验证CNHK300选择性复制和选择性杀伤能力;用细胞生长抑制实验进一步考察CNHK300与化疗药物紫杉醇联合应用对乳腺癌细胞的杀伤作用;用Western blot检测腺病毒E1A在细胞中的表达。

Because different cell lines may show various levels of susceptibility to adenovirus infection and virus production, non-selectively replicating wtAd5 was used to be a comparison with the tested conditionally replicating adenovirus CNHK500.ONYX-015, the first replication-competent adenovirus entered into clinical trials was also used to be a comparison. We used virus proliferation assay, cell viability assay and western blot to evaluate the proliferation and cytolysis selectivity of CNHK500. Results demonstrated that the CNHK500 virus proliferation multiples in breast cancer cell lines after 48 hours is similar to that of wtAd5, ONYX-015 virus proliferation ability is less than that of CNHK500 in cancer cells.

然后,通过与ONYX-015(E1B 55 KD a蛋白缺失的2型和5型嵌和型腺病毒,美国ONYX生化制药公司研制)、wtAd5进行对比,利用病毒增殖实验和细胞生长抑制实验,验证了CNHK500选择性增殖能力和肿瘤特异性杀伤作用;利用Western Blot检测CNHK500腺病毒E1A和E1B在乳腺癌细胞和正常成纤维细胞中的表达差异,揭示了腺病毒肿瘤靶向性的机制;利用携带绿色荧光蛋白的CNHK500-EGFP感染乳腺癌细胞株和正常成纤维细胞株,直观地观察其感染乳腺癌细胞的能力和在乳腺癌细胞中的增殖过程。

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歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车,和一双合并为一移交&整个lotta爱&。

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