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The joint winner of this year's Nobel Prize for Medicine, Harald zur Hausen, was recognised for his work on the human papilloma virus, which can lead to cervical cancer.

今年的医学奖得主之一,Harald zur Hausen因自己在从事会导致宫颈癌的人乳头瘤状病毒的研究而获奖。

Objective To investigate the role of human papilloma virus and fragile histidine triad protein in skin squamous cell carcinoma and relationship between them.

目的 探讨人类乳头瘤病毒和脆性组氨酸三联体基因蛋白在皮肤鳞状细胞癌中的作用及其之间的关系。

objective:study female the yin false wet you of clinical pathology characteristics and discriminate judgment.method:rightness 69example sufferer of clinical and laboratory check the data carry on analysis.result:pcv and small labium seamy side the most familiar(91.3%) skin external appearance with floss form familiar(62.3%) be located on a roe of fish form a time it;(33.33%)organization pathology show the upper part in the ji layer to fill the air a sex net basket a form empty bubble cell kind change;the acetic acid experiment a rate;(97.17%)human milk head lump virus second type examination feminine gender.conclusion:pcvhave a clinical characteristics of show the zhao, acetic acid of experiment hpv examination have importance value towards discriminate analysis.

目的:探讨女阴假性湿疣的临床病理特点及鉴别判断。方法:对69例患者的临床及实验室检查资料进行分析。结果:女阴假性湿疣及小阴唇内侧最为常见(91.3%)皮肤外观以绒毛状常见(62.3%)位于鱼子状次之(33.33%);组织病理示棘层中上部弥漫性网篮状空泡细胞样改变;醋酸的试验率(97.17%);人乳头瘤病毒亚型检测阴性。结论:女阴假性湿疣具有显著的临床特点,醋酸的试验hpv检测对鉴别分析有重要价值。

Therefore, in a newly designed three-dimensional cell culture system that fulfils the conditions necessary for odontoblast differentiation (Kikuchi et al. 2002), we examined whether dental papilla cells in rat mandibular incisors could differentiate into tubular dentine-forming cells.

本实验我们设计了另一种新的三维培养模型,来研究成牙本质细胞的分化,并观察大鼠下切牙牙乳头细胞能否形成管状牙本质。

ResultsMorphological features with diagnostic value were established as follows:①Irregular or round-mesh basket type nucleolus;②Malformed nucleus and lobate nucleus with fine bridge;③Perinuclear microfilaments;④Nuclear bodies;⑤Nuclear inclusion bodies;⑥Marked cell pleomorphism arranged irregularly,like a disordered stone pavement;⑦Strange cell and/or giant cancer cell were found;⑧Peculiar papillae or cell clusters were formed;⑨Specific function structure on the surface of cell differentiated poorly.

结果 确定了具有诊断意义的形态学特征:①不规则奇形核仁或网孔状核仁;②畸形核,分叶核伴细桥-核间桥形成;③核旁微丝;④核体;⑤核包涵体;⑥细胞重度多形性,排列紊乱,似乱石铺堆;⑦出现奇形细胞和/或癌巨细胞;⑧形成奇形乳头和奇形细胞簇;⑨细胞表面特异功能结构分化不良。

Objective To explore clinic application of endoscopic retrograde cholangiopancreatography combined with laparoscopic cholecystectomy for the treatment of the cholecystic stone combined bile duct disease.

目的 探讨逆行胰胆管造影术联合腹腔镜胆囊切除术对胆囊结石伴胆管病变治疗的临床应用方法 27例胆囊结石伴胆道病变患者,先用ERCP、乳头切开术取石;或ERCP和鼻胆管引流及柱状气囊扩张术治疗,术后3~11天,患者无发热、腹痛,血淀粉酶正常,再按常规四孔法施行LC。

An excoriation is a punctate or linear abrasion produced by mechanical means , usually involving only the epidermis but not uncommonly reaching the papillary layer of the dermis .

抓痕是由机械因素引起的点状或线状擦伤,常累及表皮,很少累及真皮乳头层。

Experimental data were acquired by LabVIEW and processed through the time-domain analysis and frequency-domain analysis with Matlab. We analyzed qualitatively the specific effect of different tastants and proved the sensitivity to salt and sourness of taste receptor cells isolated from rat fungiform papilla. These experimental results demonstrate the feasibility that the cell chip based on LAPS can be used in the study of taste transduction mechanism.

采用LabVIEW采集数据、Matlab进行时域和频域分析,我们定性分析了不同味质作用于味觉细胞后胞外电信号的变化,证实了大鼠菌状乳头的味觉细胞对于咸味和酸味的敏感性,实现了细胞芯片在味觉传导机理研究中的应用。

Had intracystic nodules. Conclusion Papillary craniopharyngiomas have characteristic pathologic and MR appearances. On MR imaging, they should be differentiated from pituitary adenoma,glioma,and metastasis.

鳞状乳头型颅咽管瘤是一组具有明确组织学及影像学特征的肿瘤,在MRI上主要与垂体瘤、下丘脑胶质瘤及转移瘤相鉴别。

The VX2 is a squamouscell carcinoma resulting from malignant change in a papilloma induced with the Shope virus in rabbits.

兔VX2肿瘤细胞系来源于Shope病毒致乳头瘤恶变形成的鳞状上皮细胞恶性肿瘤,目前已经纯化,可应用于进一步肿瘤实验研究。

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