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乙酰苯

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For example: antimalarials primaquine morpholine, flutter malaria quinoline, quinine, chloroquine, quinacrine; antibacterial drugs have sulfa drugs, chloramphenicol and furans; antipyretic analgesics are acetyl salicylic acid, phenacetin, acetanilide, antipyrine, aminopyrine; other drugs such as vitamin K, probenecid, hydralazine, quinidine, methylene blue, toluene and so on.

抗疟药伯氨喹啉、扑疟喹啉、奎宁、氯奎、阿的平;抗菌药有磺胺类药物、氯霉素及呋喃类;解热镇痛药有乙酰水杨酸、非那西丁、乙酰苯胺、安替比林、氨基比林;其它药物如维生素K、丙磺舒、肼苯哒嗪、奎尼丁、美蓝、甲苯等。

Calicheamicin can be conjugated to the non-specific antibody using a 4-(4'-acetylphenoxy) butanoic acid or (3-Acetylphenyl) acetic acid linker.

可使用4-(4′-乙酰基苯氧基)丁酸或(3-乙酰基苯基)乙酸连接子使卡奇霉素与所述非特异性抗体共轭结合。

The study mainly aims at the optima composition and suitable technological conditions of stearoylbenzoyl-methane--one of theβ- diketone compounds prepared from methyl stearate and phenyl ethyl ketone under alkaline catalysts.

主要研究采用硬脂酸甲酯和苯乙酮在强碱类催化剂作用下制备β二酮化合物之一的硬脂酰苯甲酰甲烷的最佳配方和适宜的工艺条件。

A selective and mild PS-DIB/ionic-liquid immobilized 2, 2, 6, 6-tetramethyl-piperidin-4-ol-N-oxyl catalytic oxidation procedure of alcohols to the corresponding aldehydes and ketones in ionic liquid BF4 at room temperature was developed. The oxidant PS-DIB was prepared via the iodation and acetylation of polystyrene resin. For the preparation of the ionic-liquid immobilized TeMPO catalyst, 4-(2, 2, 6, 6-Tetramethyl-1-oxyl-4-piperidoxyl)butyl bromide was first synthesized from TeMPO and 1, 4-dibromobutane.

将聚苯乙烯树脂先碘化再乙酰基化,制得了负载型二乙酰氧碘苯作为氧化剂。2, 2, 6, 6-四甲基-N-氧自由基哌啶醇与1, 4-二溴丁烷反应生成4-溴丁氧基-2, 2, 6, 6-四甲基-哌啶-1-氧化物,再与N-甲基咪唑发生季铵化反应,生成的溴化季铵盐与四氟硼酸钠进行离子交换制得氟硼酸型2, 2, 6, 6-四甲基-N-氧自由基哌啶负载离子液体。

A selective and mild PS-DIB/ionic-liquid immobilized TEMPO catalytic oxidation procedure of alcohols to the corresponding aldehydes and ketones in ionic liquid BF4 at room temperature was developed. The oxidant PS-DIB was prepared via Iodation and acetylation of polystyrene resin. For the preparation of the ionic-liquid immobilized TEMPO catalyst, 4-(2,2,6,6-Tetramethyl-1-oxyl-4-piperidoxyl)butyl bromide was first synthesized from 2,2,6,6-tetramethyl-piperidin-4-ol-N-oxyl and 1,4-dibromobutane.

将聚苯乙烯树脂先碘化再乙酰基化,制得了负载型二乙酰氧碘苯(diacetoxyiodo polystyrene,PS-DIB)作为氧化剂。2,2,6,6-四甲基-N-氧自由基哌啶醇(2,2,6,6-tetramethyl-piperidin-4-ol-N-oxyl,TEMPO)与1,4-二溴丁烷反应生成4-溴丁氧基-2,2,6,6-四甲基-哌啶-1-氧化物,再与N-甲基咪唑发生季铵化反应,生成的溴化季铵盐与四氟硼酸钠进行离子交换制得氟硼酸型2,2,6,6-四甲基-N-氧自由基哌啶负载离子液体TEMPO-IL。

In a system consisting of 20% PEG 400 and 12% magnesium sulfate, the partition coefficient of PGA was less than 0.01, PGA almost completely partitioned into the magnesium sulfate-rich bottom phase. Meanwhile, the partition coefficient of cephalexin was 6.7, the partition coefficients of phenylglycine methyl ester and 7-ADCA were 1.5 and 1.2, respectively.

通过考察头孢氨苄、苯甘氨酸甲酯和7-氨基脱乙酰氧基头孢烷酸(7-ADCA)在ATPS中的分配行为建立了一个含20%PEG 400和12%硫酸镁的ATPS,在此体系中头孢氨苄的分配系数为6.7,苯甘氨酸甲酯的分配系数为1.5,7-ADCA的分配系数为1.2,且青霉素酰化酶的分配系数小於0.01。

They are 4-(2- hydroxy-3-butynlenoxy) benzoic acid (1, WA), 5-chloro-7, 8-dihydroxy-7-methyl- 6-oxo-3- [ -3, 4-dihydroxy-3, 5-dimethyl-l-heptylene] -1H-8, 8a-dihydrobenzo [2, 3-c] pyran (2, WB),-2-(2-methyl-2-dibutene diamido)-2-butenoic acid (3, B5262), 3, 4-dihydro-9, 10-dihydroxy-7-methoxy-3-methyl-1H-naphtho [2, 3- c] pyran-1-one (4, A73 semi-Vioxanthin), 8, 8'-bis (6, 9-dioxo-3,4-dihydro-10- hydroxy-7-methoxy-3-methyl-1H-naphtho [2, 3-c] pyran-1-one)(5, A122 Xanthomegnin), 2, 5-dioxo-3a-hydroxymethyl-3, 3a, 6, 6a-tetrahydro-furo [2, 3-b] furan (6, 1003-2), 7-acety1-5-chloro-6, 8-dioxo-7-methyl-3- [ -3, 5-dimethyl-1, 3- diheptylene] -4aH-benzo [2, 3-c] pyran (7, M2-2 sclerotiorin), respectively.

它们分别被命名为4-(2-羟基-3-丁炔氧基)苯甲酸(1,WA)、5-氯-7,8-二羟基-7-甲基-6-氧代-3-[-3,4-二羟基-3,5-二甲基-1-庚烯基]-1H-8,8a-二氢苯并[2,3-c]吡喃(2,WB)、-2-(2-甲基-2-丁烯二酰亚胺基)-2-丁烯酸(3,B5262)、3,4-氢-9,10-二羟基-7-甲氧基-3-甲基-1H-萘并[2,3-c]吡喃-1-酮(semi-Vioxanthin,4,A73)、8,8'-双(6,9-二氧代-3,4-二氢-10-羟基-7-甲氧基-3-甲基-1H-萘并[2,3-c]吡喃-1-酮)(Xanthomegnin,5,A122)、2,5-二氧代-3a-羟甲基-3,3a,6,6a-四氢-呋喃并[2,3-b]呋喃(6,1003-2),7-乙酰基-5-氯-6,8-二氧代-7-甲基-3-[-3,5-二甲基-1,3-庚二烯基]-4aH-苯并2,3-c]吡喃(Sclerotiorin,7,M2-2)。

In the fifth chapter, a series of betulin derivatives including 28-acetoxybetulin, 28-tritylbetulin, 28-benzoylbetulin, 3-0-P-D-glucopyranoside of betulin and some betulinic acid conjugate containing amino acid were synthesized and confirmed by MS and NMR.

第五章分别合成得到了乙酰化白桦酯醇、28-苯甲酰化白桦酯醇、28-三苯甲基化白桦酯醇、3-O-β-D-glucopyranoside of betulin和一系列的白桦酯酸苷氨酸的衍生物,并分别对其进行了结构鉴定。

In the fifth chapter, a series of betulin derivatives including 28-acetoxybetulin, 28-tritylbetulin, 28-benzoylbetulin, 3-O-β-D-glucopyranoside of betulin and some betulinic acid conjugate containing amino acid were synthesized and confirmed by MS and NMR.

第五章分别合成得到了乙酰化白桦酯醇、28-苯甲酰化白桦酯醇、28-三苯甲基化白桦酯醇、3-O-β-D-glucopyranoside of betulin和一系列的白桦酯酸苷氨酸的衍生物,并分别对其进行了结构鉴定。

Furoin was synthesized from furol with VB1 as the catalyst,which was then reacted with acetyl chloride, lauroyl chloride ,benzoyl chloride,α-furoyl chloride and 3-α-furyl acryloyl chloride,respectively;corresponding monoester compounds of furoin were synthesized in THF in the presence of sodium hydroxide under reflux.

以糠醛为基础原料,经维生素B1催化合成糠偶姻,再由糠偶姻分别和乙酰氯、月桂酰氯、苯甲酰氯、α-呋喃甲酰氯和3-α-呋喃烯丙酰氯反应,在NaOH/无水THF体系中,于水浴回流条件下合成了相对应的糠偶姻单酯类化合物。

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