乙酰脲

Eight novel N,N′-naphthalene acyl substituted aromatic acylamino thiocarbamide s(Ⅱ1~Ⅱ8) were synthesized from aryl acylhydrazine and α-naphthalene acyl isothiocyanate, which was obtained by the reaction of potassium thiocyanate with α-naphthalene acyl chloride obtained from 2-naphthylacetic acid and thionyl chloride in anhydrous benzene.

通过α-萘乙酸和SOCl2在无水苯中反应制得α-萘乙酰氯，与硫氰酸钾反应生成α-萘乙酰基异硫氰酸酯，再与芳基酰肼进行加成反应，合成8种新型N，N′-萘乙酰基取代芳乙酰胺基硫脲类化合物(Ⅱ1～Ⅱ8)。

A novel compound——N-naphthalene acylN′-substituted p-chlorobenzamido thiocarbamide was synthesized by reaction of p-chlorobenzamido hydrazine and α-naphthalene acyl mustard oil,which was obtained by potassium thiocyanate combined with α-naphthalene acyl chloride formed from α-naphthylacetic acid and SOCl2 in anhydrous benzene.

通过α-萘乙酸和SOCl2在无水苯中反应制得α-萘乙酰氯，然后与硫氰酸钾反应生成α-萘乙酰基异硫氰酸酯，再与对氯苯甲酰肼进行加成反应，合成了新型化合物N-萘乙酰基-N′-对氯苯甲酰氨基硫脲，用薄层色谱法跟踪最后一步反应，确定了反应时间。

Naphthalene acetyl chloride was prepared firstly by the reaction between α-naphthylacetic acid and SOCl2 in anhydrous benzene,then reacted with potassium thiocyanate to obtain α-naphthalene acetyl isosulfocyanate,as taking an addition reaction with p-chloro benzoyl hydrazine the novel compound N-naphthalene acetyl-N'-p-chloro benzoylamino thiocarbamide was finally synthesized.

通过α-萘乙酸和SOC l2在无水苯中反应制得α-萘乙酰氯，然后与硫氰酸钾反应生成α-萘乙酰基异硫氰酸酯，再与对氯苯甲酰肼进行加成反应，生成新型化合物N-萘乙酰基-N'-对氯苯甲酰氨基硫脲。

Naphthalene acetyl chloride was prepared firstly by the reaction betweenα-naphthylacetic acid and SOCl2 in anhydrous benzene, then reacted with potassium thiocyanate to obtainα-naphthalene acetyl isosulfocyanate, as taking an addition reaction with p-chloro benzoyl hydrazine the novel compound N-naphthalene acetyl-N'-p-chloro benzoylamino thiocarbamide was finally synthesized.

通过α-萘乙酸和SOCl2在无水苯中反应制得α-萘乙酰氯，然后与硫氰酸钾反应生成α-萘乙酸基异硫氰酸酯，再与对氯苯甲酰肼进行加成反应，生成新型化合物N-萘乙酰基－N'-对氯苯甲酰氨基硫脲。

Eight novel N,N′-naphthalene acyl substituted aromatic acylamino thiocarbamides(Ⅱ1~Ⅱ8) were synthesized from aryl acylhydrazine and α-naphthalene acyl isothiocyanate, which was obtained by the reaction of potassium thiocyanate with α-naphthalene acyl chloride obtained from 2-naphthylacetic acid and thionyl chloride in anhydrous benzene.

通过α-萘乙酸和SOCl2在无水苯中反应制得α-萘乙酰氯，与硫氰酸钾反应生成α-萘乙酰基异硫氰酸酯，再与芳基酰肼进行加成反应，合成8种新型N，N′-萘乙酰基取代芳乙酰胺基硫脲类化合物(Ⅱ1～Ⅱ8)。

Ingredients: Water,Lauric Acid,Myristic Acid,Stearic Acid,Propylene Glocol,Potassium Hydroxide,Cocamidopropyl Betaine,Starch Hydroxypropyltrimnium Chloride,Sodium Laureth Sulfate,Glycol Distearate,Lavandula Angustifolia Oil,Creatine,Tetrasodium Edta,Perfume,Dmdm Hydantoin.

成分： 去离子水，月桂酸，肉豆蔻酸，硬脂酸，丙二醇，氢氧化钾，椰油酰胺丙基甜菜碱，淀粉羟丙基三甲基氯化铵，月桂醇聚醚硫酸钠，乙二醇双硬脂酸酯，薰衣草精油，肌酸，乙二胺四乙酸四钠，香精，DMDM 乙内酰脲。

NOBS PAG , can obviously activate hydrogen peroxide thus , the efficiency of hydrogen peroxide bleaching can be advanced greatly .

研究结果初步表明，此类有机酰化剂类如：四乙酰乙二胺，四乙酰甘脲，异壬酰氧基苯磺酸钠，五乙酰葡萄糖等有着非常明显的活化过氧化氢的作用，从而能在很大程度上提高纸浆过氧化氢漂白的效率。

The famciclovir was synthesized from purine by a series of steps by Acylation, Decarboxylation, Reduction ,and so on; Derivatives of these intermediates is described from the 6-chloro- 9H- purin-2-amine as raw materials in different conditions when the iodine and bromide were synthesized with the addition of two intermediate 6-bromo-9H-purin-2-amine and 6-iodo-9H-purin-2-amine; There is elaborated from the main part of a acetophenone, urineaminohydrochloride, phenylhydrazine, ethyl acetoacetate as raw material through a series of reactions to synthetic 3-phenyl-4-formylphenyl pyrazole and 5-chloro-3-methyl-1-phenyl-1H-pyrazole-4-aldehyde two pyrazole aldehyde, and then with 2-amino-6-chlorine-9-(2-methicillin-oxo-co-methyl-4-yl) purine reaction of the two new pyrazole purine Schiff bases.

本论文主是采用以鸟嘌呤为原料，经过一系列的酰基化，脱羧，还原等反应作用下最终得到了产物2-氨基-9-(4-乙酰氧基-3-乙酰氧基甲基丁基)嘌呤；其中的中间体衍生物主要是阐述从以2-氨基-6-氯鸟嘌呤为原料通过在不同的条件下进行溴代与碘代分别合成了另外两种中间体2-氨基-6-溴鸟嘌呤及2-氨基-6-碘鸟嘌呤；还有一部分主要是阐述从以苯乙酮，盐酸氨基脲，苯肼，乙酰乙酸乙酯为原料通过一系列的反应先合成3-苯基-4-醛基吡唑及5-氯-3-甲基-1-苯基-1H-吡唑-4-甲醛这两个吡唑醛，然后再与2-氨基-6-氯-9-(2-甲氧羰基丁酸甲酯-4-基)嘌呤反应得到了两个新型的吡唑嘌呤席夫碱

In the first part, five new 4-acyl pyrazolone 4-ethyl-thiosemicarbazones compounds: 1-Phenyl-3-methyl-4-(4-bromo)benzal-pyrazol-5-one N(4)-ethyl-thiosemicarbazone (PM4Br BP-ETSC), 1-Phenyl-3-methyl-4-(4-methyl)benzal-pyrazol-5-one N(4)-ethyl-thiosemicarbaz -one (PM4MBP-ETSC), 1-Phenyl-3-methyl-4-benzal-pyrazol-5-one N(4)-ethyl-thiosemicarba -zone, 1,3-diphenyl-4-benzal-pyrazol-5-one N(4)-ethyl-thiosemicarbazone and 1-Phenyl-3-methyl-4-phenylacetyl-pyrazol-5-one N(4)-ethyl-thiosemi -carbazone have been synthesized and characterized by elemental analyses, IR, 1H NMR spectra and single-crystal XRD.

第一部分合成了五个4-酰基吡唑啉酮缩4-乙基-氨基硫脲化合物：1-苯基-3-甲基-4-（4-溴）苯甲酰基-5-吡唑啉酮缩4-乙基-氨基硫脲(PM4BrBP-ETSC)，1-苯基-3-甲基-4-(4-甲基)苯甲酰基-5-吡唑啉酮缩4-乙基-氨基硫脲(PM4MBP-ETSC)，1-苯基-3-甲基-4-苯甲酰基-5-吡唑啉酮缩4-乙基-氨基硫脲，1，3-二苯基-4-苯甲酰基-5-吡唑啉酮缩4-乙基-氨基硫脲和1-苯基-3-甲基-4-苯乙酰基-5-吡唑啉酮缩4-乙基-氨基硫脲，其中前四个具有光致变色性质。

On the basis of the complex structures of AHAS and sulfonylureas inhibitors, systematic molecule docking study of five sulfonylureas inhibitors to AHAS were performed with autodock 3.0 package.

基于酵母乙酰羟酸合成酶与磺酰脲类抑制剂复合物的晶体结构，用分子对接方法对AHAS与5个磺酰脲类抑制剂相互作用的方式进行了系统的分子对接研究。

Now, however, all children continue in "comprehensive" schools, and the eleven-plus determines which courses of study the child will follow.

然而现在，所有的孩子都要在综合学校继续学习，所以这次考试只是决定他们将要学习哪些课程。

Cultivatable land , and led to a general recognition that development must not be carried at the cost of agriculture .

城区的迅速扩大在很多情况下侵占了宝贵的可耕地，使人们普遍认识到发展不能以牺牲农业为代价。