乙酰胺

The results indicate that the optimized sulfonylation reaction time is 4 h, the materiel rate of chlorosulfonic acid and 2-chloroimidazo[1,2-α]pyridine is 1.2 : 1, with ethylamine the yield increasing from 15.4% to above 70%; the optimized ammonolysis reaction time is 3 h and the reaction temperature is 27℃, with the acetonitrile yield increasing from 60.1% to above 79.6%.

实验结果表明，磺酰化反应的最佳反应时间为4 h，氯磺酸与2-氯咪唑并[1，-α]吡啶的用量比为1.2：1，加入三乙胺可将收率由15.4%提高到70%以上；氨解反应的最佳反应时间为3 h，反应温度为27 ℃，加入乙腈可将收率由60.1%提高到79.6%；方案经改进后，总反应时间缩短3 h，收率提高了5.5%。

Acylamino acid-5-fluorouracil were prepared from acylamino acid chlorides and 5- fluorouracil in the presence of 〓.

邻苯二甲酰氨基酸酰-5-氟尿嘧啶则由邻苯二甲酰氨基酸酰氯与5-氟尿嘧啶在三乙胺的存在下制得。

Study on an efficient process for the preparation of trifloxystrobin starting from 2-methylacetophenone bypartial oxidation,esterification,reaction with methoxyamine,bromization and condensation with 3'- acetophenone oxime.

以邻甲基苯乙酮为原料，经过高锰酸钾的碱性氧化，甲醇酯化，再与甲氧基胺盐酸盐肟化后，用N-溴丁二酰亚胺溴化，最后和间三氟甲基苯乙酮肟缩合得到目标产物肟菌酯。

In this thesis,three copolymerization systems have been investigated in detail.They are α-ethylacrylic acid/maleimide,α- acrylic acid/maleimide and monomethyl itaconate/maleimide,respectively.

本文对α-乙基丙烯酸/马来酰亚胺、α-正丙基丙烯酸/马来酰亚胺和衣康酸单甲酯/马来酰亚胺三种新的共聚体系进行了详细地研究，并对合成共聚物的生理活性进行了初步探讨，实现了α-正丙基丙烯酸乙酯/马来酰亚胺体系的可控共聚反应。

Amino-monomethoxypoly(ethy1ene glycol)(mPEG-NH2) was synthesized based on the principle of Gabriel synthesis.Monomethoxypoly(ethy1ene glycol) tosylate was prepared at first,and then reaction with potassium salt of phthalimide as nucleophile to produce the monomethoxypoly(ethy1ene glycol)phthalimide derivative.

摘 要：首先合成了单甲氧基聚乙二醇对甲苯磺酸酯，然后根据盖布瑞尔合成法原理，以邻苯二甲酰亚胺钾盐为亲核试剂与mPEG-OTs反应，生成单甲氧基聚乙二醇的邻苯二甲酰亚胺衍生物，mPEG-PI与水合肼反应肼解生成伯胺，合成了一端为氨基的单甲氧基聚乙二醇(mPEG-NH2)。

Gabriel reaction was adopted to synthesis 2-(0ctahydro-1-azocinyl)ethylamine, N-(β-Heptamethyleniminoethy1)phthalimide was prepared by treating Heptamethylenimine with N -(β-bromoethy1) phthalimide. N -(β-bromoethy1) phthalimide was easily prepared from phthalic anhydride in two steps.

我们采用Gabriel伯胺合成法制备2-环庚亚胺基乙胺，从邻苯二甲酸酐经过两步反应很容易地得到N-邻苯二甲酰亚胺，然后与环庚亚胺发生亲核取代反应，产物再水解制得伯胺2-环庚亚胺基乙胺。

The hydrophobic core serves as a reservoir for water-insoluble drugs.Hence,these nanoparticles can be used as carriers for hydrophobic drugs.For the synthesis of cholesterol-modified glycol chitosan conjugates,a carboxyl group was initially introduced to cholesterol molecule using succinic anhydride,and then covalently coupled with the primary amino group of glycol chitosan in the presence of 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide hydrochloride and N-hydroxyl succinimide.

本文采用二步反应将胆固醇接枝到乙二醇壳聚糖，首先将胆固醇进行羧基化，将胆固醇与琥珀酸酐反应生成胆固醇半琥珀酸酯，然后用1-乙基-3-(3-二甲基氨丙基)碳二亚胺盐酸盐与N-羟基琥珀酰亚胺作为偶联剂，将胆固醇半琥珀酸酯的羧基与乙二醇壳聚糖主链的氨基进行反应，得到胆固醇疏水改性乙二醇壳聚糖共聚物。

With land area of 2,800M2 and completed quality supervision test instrument, its annual sales amount reaches 30,000,000 RMB. Its main products, Succinimide,butanimide,2.5-diketopyrrolidine;N-bromobutanimide or N-bromosuccinimide;N- chlorosuccinimide (N-chlorobutanimide);Bromoacetonitrile,Bromomethyl cyanide; Quinoline;P-Bromophenol;4-Bromophenol;N.N'- dicyclohexylcarbodiimide;S-3-Hydroxy-γ-Butyrolactone;2.3-Dihydrofuran;Ammonia water, Ammonium hydroxide; sell well in the US, South Korea, Europe and other countries and are praised highly by all clients.

占地面积2800M2，年销售额3000万元，公司拥有完备的质量监测检验仪器和手段，主要产品有：琥珀酰亚胺、N-溴代琥珀酰亚胺、N-氯代琥珀酰亚胺、溴乙晴、喹啉（95%）、喹啉（ 98%）、对溴苯酚、N.N'-二环已基碳化二亚胺、s-3-羟基-γ-丁内酯、2.3-二氢呋喃、氨水、氢氧化胺，产品远销美国、韩国、欧洲等国家和地区，深受用户青睐。

All of the tripodal schiff base ligands and their complexes were characterized.

以三乙醇胺、巯基苯胺、巯基乙胺为初始原料，设计合成了六个三脚架结构的化合物，其合成路线如下：三乙醇胺与氯化亚砜反应得到三(2-氯乙基)胺(1)，然后与巯基苯胺或巯基乙胺在碱性条件下反应生成三脚架结构的三{[2-(2-氨基苯基)硫代]乙基}胺(2)或三{[2-(2-氨基乙基)硫代]乙基}胺(3)，然后再与水杨醛、2-甲酰基-8-羟基喹啉(8)、2-甲酰基-8-苄氧基喹啉(7)反应得到六种新型的含硫西佛碱化合

In this thesis, the design, synthesis and application of substituted 1,8-naphthalimides and napthopyrones conjugated with uridine, substituted 1,3,5-triazine, 1,2-dibromoethane, ethyl bromoacetate have been studied.

本论文研究了取代l，8-萘酰亚胺和萘并吡喃酮与尿苷、取代均三嗪、二溴乙烷、溴乙酸乙酯偶合和双l，8-萘酰亚胺之间偶合的设计、合成及应用。

And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

47：5 法老对约瑟说，你父亲和你弟兄们到你这里来了。

Additionally, the approximate flattening of surface strip using lines linking midpoints on perpendicular lines between geodesic curves and the unconditional extreme value method are discussed.

提出了用测地线方程、曲面上两点间短程线来计算膜结构曲面测地线的方法，同时，采用测地线间垂线的中点连线和用无约束极值法进行空间条状曲面近似展开的分析。