乙酰甲基

Several epigenetic drugs targeting DNA methylation and histone deacetylation enzymes have been tested in clinical trials.

靶向DNA甲基化和组蛋白去乙酰化酶的几个表观药物已经在临床试验中被测试。

DNA methylation is usually associated with triggering histone deacetylation, chromatin condensation, and gene silencing.

DNA甲基化通常与组蛋白脱乙酰化、染色质浓缩和基因沉默相关，染色质浓缩，和基因沉默。

Methylation production were hydrolyzed, deoxidize, then analyzed by GC-MS.

甲基化产物经酸水解、还原、乙酰化后用GC-MS联机分析。

During the two critical periods—gametogenesis and preimplantation development, there are genome-wide epigenetic reprogramming in gametes and embryos, which plays important roles in the erasion or creation of imprinting, gene silencing and tissue-specific gene expression.

其中关键时期是配子形成期和胚胎植入前期，最主要内容是全基因组DNA"CpG岛"甲基化和染色质组蛋白乙酰化的有规律变化，结果是配子遗传印记的消除与重建、植入前胚胎大范围基因的静默和组织特异性基因表达的确定。

In addition, the effects of temperature and concentration of sulfuric acid on the concentration of LA and 5-hydroxymethyl furfural were shown.

实验考察了不同温度和硫酸浓度对葡萄糖分解的主要产物5-羟甲基糠醛和乙酰丙酸浓度的影响。

Ribose/galactose/methyl galactoside importing ATP-binding protein 1 was participated in photosynthates transportation from leaf to grain in early and mid-stages.

分析结果表明，核糖／半乳糖／甲基半乳糖苷运输ATP结合蛋白l在灌浆前中期参与物质向籽粒的运输；生长素响应蛋内IAA27通过调节ATPase活性影响叶片物质运输；N-乙酰谷氨酸半醛脱氢酶在灌浆末期参与叶片的多胺代谢，延缓叶片衰老；谷胱甘肽S-转移酶和Cu/Zn-超氧化物歧化酶在籽粒灌浆后期的植物解毒和防御活性氧伤害中起着重要作用。

Halogen acetylized crosslinked polystyrene resin is used for replacing commonly used methyl chloride polystyrene resin.

用卤乙酰化聚苯乙烯树脂代替了通常所用的氯甲基聚苯乙烯树脂。

We found that NaBu stimulated ALAS2 gene expression not only in erythroid K562 cells, but also in non-erythroid 293T cells with a concurrent increase in acetylation level of histone H3 and dimethylation level of K4 at the same histone at ALAS2 gene promoter.

同时ALAS2基因启动子的组蛋白H3乙酰化水平以及组蛋白H3的第4位赖氨酸的双甲基化水平升高。

Noma de México and the Instituto Nacional de Cancerolog?a, Mexico, demonstrate, for the first time, that a combination of a DNA methylation and a histone deacetylase inhibitor, can reactivate the expression of more than a thousand genes in primary tumours of breast cancer patients.

在PLoS ONE开始的一期，来自墨西哥国家癌症研究所和国家Aut大学Investi gaciones Biomédicas研究所的Due馻s-Gonzalez博士领导研究组第一次证明DNA甲基化和组蛋白去乙酰化的抑制物联合可以使乳腺癌患者在初期肿瘤时超过一千个基因的表达失活

Noma de México and the Instituto Nacional de Cancerolog?a, Mexico, demonstrate, for the first time, that a combination of a DNA methylation and a histone deacetylase inhibitor, can reactiate the expression of more than a thousand genes in primary tumours of breast cancer patients.

在PLoS ONE开始的一期，来自墨西哥国家癌症研究所和国家Aut大学Inesti gaciones Biomédicas研究所的Due as-Gonzalez博士领导研究组第一次证明DNA甲基化和组蛋白去乙酰化的抑制物联合可以使乳腺癌患者在初期肿瘤时超过一千个基因的表达失活

And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

47：5 法老对约瑟说，你父亲和你弟兄们到你这里来了。

Additionally, the approximate flattening of surface strip using lines linking midpoints on perpendicular lines between geodesic curves and the unconditional extreme value method are discussed.

提出了用测地线方程、曲面上两点间短程线来计算膜结构曲面测地线的方法，同时，采用测地线间垂线的中点连线和用无约束极值法进行空间条状曲面近似展开的分析。