乙酰氯

The final product Rimonbant was then obtained in 64% yield via chlorination of the acid with oxalyl chloride followed by treatment of the resultant acyl chloride with 1-aminoperidine.

酰氯与1-氨哌啶在三乙胺存在下缩合生成目标产物利莫那班，产率64%。

Cefixime open side chain acid was prepared by oximation,etherification,chlorination,ester decomposition using t-butyl acetoacetate as starting material.

以乙酰乙酸叔丁酯为原料，经过肟化、醚化、氯代酯解反应合成了头孢克肟开环侧链酸。

Synthesis of Organic Pigmet Intermidiate N, N'- bisacetylaceto - 2 - methyl - 5 - chloro -1,4- Phenylenediamine

有机颜料中间体N，N′-双乙酰乙酰基2-甲基-5-氯代-1，4-苯二胺的合成

In order to search for the new pyrazolyl-heterocycles lead compounds, eight pyrazolyl- were synthesized from 3-ethyl-1-methyl- 4-substituted-5-pyrazolecarboxylic acid chloride and nitrogen heterocyclic rings such as 3-methyl-5-pyrazolone, 1H-3-ethyl-5-pyrazole ester, etc.

为了寻求新的含吡唑双杂环先导化合物，用 4 取代 1 甲基 3 乙基 5 吡唑甲酰氯与 3 甲基 5 吡唑酮、3 乙基 5 吡唑甲酸乙酯等含氮杂环反应得到了 8个新的含吡唑环的双杂环类化合物。

With sodium acetate as catalyst, inosine was esterified with acetic anhydride in the yield of 92% to give 2',3',5'-triacetyl inosine, which was treated with pyridine and phosphorus oxychloride to form a pyridinium solution, followed by performing an amination at 40℃ and 0.25~0.30 MPa to achieve adenosine in the yield of 67%.

肌苷在醋酸钠存在下与醋酸酐发生酯化反应以92%的收率得到2'，3'，5'-三乙酰肌苷，其化合物经吡啶和三氯氧磷处理形成吡啶盐溶液，未分离直接在40℃、0.25~0.30 MPa压力下进行氨解反应以67%产率制得腺苷。

The ligand of the chiral Schiff base and acetylacetone vanadium are subjected to complexation in situ, hydrogen peroxide is taken as an oxidant, aryl alkyl thioether asymmetric oxidation reaction is catalyzed in a toluene or dichloromethane solution under low temperature or room temperature, enantioselectivity of chiral sulphoxide is 72 percent to 95 percent ee, and yield is 42 percent to 83 percent.

将上述手性西佛碱配体与乙酰丙酮氧钒原位络合，采用双氧水为氧化剂，在甲苯或二氯甲烷溶液中低温至室温下催化芳基烷基硫醚不对称氧化反应，手性亚砜的对映选择性为72％-95％ee，产率为42％-83％。

Phenothiazines were also oxidized byiodine and 2, 2, 6, 6- tetramethyl - 4 - acetyloxypiperidineoxoammonium hexachloroantimonate to radical cations in the cavityof β-cyclodextrins in aqueous solution.

以吩噻嗪衍生物为底物，2，2，6，6-四甲基-4-乙酰氧基哌啶氧铵六氯锑酸盐、碘为氧化剂，二者在水相中β-环糊精腔内发生了单电子转移反应，产生了吩噻嗪衍生物正离子自由基。

Two oligosaccharides, a hexasaccharide fragment of group E Streptococcus polysaccharide and a tetrasaccharide repeating unit of E. coli O7: K98: H6, consisting of α-(1→2)-and α-(1→3)-linked rhamnose backbones were synthesized in a regio-and-stereoselective manner.

以三氯乙酰亚胺酯为供体，不保护或部分保护的糖为受体，成功地合成了以α-（1→2）-和-α（1→3）-交替连接的鼠李糖为主链的GroupE Streptococcus六糖和E.coli O7：K98：H6四糖。

Ten novel derivatives of 1-phenyl-5-[5-(substituted anilinocarbonylmethylthio)-4-phenyl-1,2,4- triazol-3-ylmethylthio]-tetrazole were synthesized rapidly in high yields by the reaction of N--2-chloryacetanilide (3) with 1-phenyl-5-(5-mercapto-4-phenyl-1,2,4-triazol-3-ylmethylthio)-tetrazo- le (2) under microwave irradiation and phase transfer catalysis conditions.

采用微波和相转移催化法通过1-苯基-5-(4-苯基-1，2，4-三唑-5-巯基-3-甲硫基)四唑(2)与2-氯乙酰芳胺(3)反应高效、快速地合成了10种尚未见文献报道的1-苯基-5-[5--4-苯基-1，2，4-三唑-3-甲硫基]四唑。其结构经IR，1HNMR，13CNMR和元素分析表征。生物活性实验结果表明，该类化合物在较低浓度下部分化合物对小麦芽有很好的促进作用

Twenty-eight new organophosphorus compounds were prepared by reaction of sodium thio- or dithiophosphates with α-chloroacylamides.

通过硫代磷酸酯钠盐同2-α-氯代乙酰氨基噻唑或其衍生物的缩合，合成了通式为Y(R=Me、Et、i-Pr；X=O、S；Y=H、NO_2、SCN、Cl、SEt)的新有机磷化合物28个。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。