乙酰化的

Objective:To investigate the relationship between p21WAF1 gene expression and histone acetylation in gastric cancer.

简介： 目的：探讨胃癌组织p21WAF1基因表达与组蛋白乙酰化的关系。方法：利用RT-PCR对53例原发性胃癌的癌组织、癌旁组织和正常胃黏膜的p21WAF1 mRNA表达进行分析；同时对其中p21WAF1 mRNA表达失活或表。。。

DDS was used as test drug for determination of acetylator phenotype employing HPLC.The results showed that both the occupational and non-occupational exposed group were predominantly slow acetylators(52.2％and 45.5％),higher than that in the exposed controls(13.0％)(0 05).The risks for bladder cancer with the slow ace...

结果表明。无论有无2－萘胺职业接触史，膀胱癌病人中慢型乙酰化者所占比例（52.2％和45.5％）均高于对照组（13.0％），且差异有显著性（P＜0.05），比值比0R分别为5.56（95％可信限＝1.02～30.3）和7.25（95％可信限＝1.70～30.3），提示慢型乙酰化者若暴露于2－萘胺更易患膀胱肿瘤，乙酰化慢表型是膀胱癌的一个遗传易感因素。

Bromodomain is an evolutionally conserved domain that wasrecently identified in many living organisms. Bromodomain containingprotein has specific affinity to combine with acetylated lysines onN-terminal tails of histones.

溴区结构是近年来发现的广泛存在于多种生物中的一种高度保守结构域，可特异性地与组蛋白末端乙酰化的赖氨酸位点结合。

The main results and conclusions are as followings.1, The histone deacetylase inhibitors were used to feed the larve of the fly, and then the polytene chromosomes were observed under the microscope.

得到的主要结果和结论如下： 1，通过用去乙酰化酶抑制剂处理果蝇幼虫，观察果蝇多线染色体在热休克基因处的形态变化，发现去乙酰化酶抑制剂介导的乙酰化水平的升高可引起染色体结构的显著变化，推测乙酰化修饰不仅影响分子间的相互作用而且还可以影响染色体的高级结构。

"We looked at the status of the histones and found surprisingly that thymoquinone increased the acetylation process," Dr.

&我们观察组蛋白的状态并且令人惊讶地发现百里香醌能增强乙酰化的过程& Dr。

Here, we show that human HSF1 is inducibly acetylated at a critical residue that negatively regulates DNA binding activity.

在本文中，我们讲述了人类热休克因子1负性调节DNA结合活性的重要残基被诱导乙酰化的过程。

Thederivatives of 5 kinds of monosaccharides Xyl, Ara, Man, Glc, Gal were detected anddetermined respectively by GC-MS. The influences of several factors, such asreductive time, reductive temperature, acetylating temperature and acetylating time,on recovery of monosaccharides were studied by orthogonal experiments. The resultsshowed that the reductive temp.

利用气相色谱—质谱联用技术检测五种常见单糖(木糖、阿拉伯糖、甘露糖、葡萄糖、半乳糖)的乙酰化产物含量，采用正交试验综合考察了还原时间、还原温度、乙酰化温度、乙酰化时间等因素对单糖回收率的影响及规律。

Base played a crucial role in this reaction: in the Pd2/L1 catalyzed α-arylation of ethyl malonate, K3PO4 is the base of choice; in the α-arylation of ethyl acetoacetate, K2CO3 is the most effective base.

在这类催化反应中，碱的选择具有重要的影响：以K3PO4为碱， Pd2/L1催化体系在丙二酸二乙酯的α-芳基化中，富电子溴代芳烃显示较好的活性； Pd2/L1催化的乙酰乙酸乙酯α-芳基化时，以 K2CO3为碱，催化体系显示较好的活性，这个催化体系可控制反应得到α-芳基乙酰乙酸乙酯，而不是脱乙酰基的产物。

Base played a crucial role in this reaction: in the Pd2/L1 catalyzed α-arylation of ethy malonate, K3PO4 is the base of choice; in the α-arylation of ethyl acetoacetate, K2CO3 is the most effectiv base.

在这类催化反应中，碱的选择具有重要的影响：以K3PO4为碱，Pd2/L1催化体系在丙二酸二乙酯的α-芳基化中，富电子溴代芳烃显示较好的活性；Pd2/L1催化的乙酰乙酸乙酯α-芳基化时，以K2CO3为碱，催化体系显示较好的活性，这个催化体系可控制反应得到α-芳基乙酰乙酸乙酯，而不是脱乙酰基的产物。

Glycosidic bond of chitin could be cut off selectively in the degradation of chitin and soluble chitin of part deacetylation could be obtained.

甲壳质的酶法降解，可选择性地切断甲壳质的β-1，4-糖苷键，可得到部分脱乙酰化的可溶性甲壳质。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。