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In eukaryotes, the acetylation of histones was discovered many years ago.

在真核生物中,很早就发现了组蛋白的乙酰化现象。

This article introduces a simple method, which is acetylation method, to determinate the hydroxy content in petroleum oxidation products.

文章介绍了一种测定石油氧化物中羟值的简便方法——乙酰化法。

The results indicate that the optimized sulfonylation reaction time is 4 h, the materiel rate of chlorosulfonic acid and 2-chloroimidazo[1,2-α]pyridine is 1.2 : 1, with ethylamine the yield increasing from 15.4% to above 70%; the optimized ammonolysis reaction time is 3 h and the reaction temperature is 27℃, with the acetonitrile yield increasing from 60.1% to above 79.6%.

实验结果表明,磺酰化反应的最佳反应时间为4 h,氯磺酸与2-氯咪唑并[1,-α]吡啶的用量比为1.2:1,加入三乙胺可将收率由15.4%提高到70%以上;氨解反应的最佳反应时间为3 h,反应温度为27 ℃,加入乙腈可将收率由60.1%提高到79.6%;方案经改进后,总反应时间缩短3 h,收率提高了5.5%。

In a system consisting of 20% PEG 400 and 12% magnesium sulfate, the partition coefficient of PGA was less than 0.01, PGA almost completely partitioned into the magnesium sulfate-rich bottom phase. Meanwhile, the partition coefficient of cephalexin was 6.7, the partition coefficients of phenylglycine methyl ester and 7-ADCA were 1.5 and 1.2, respectively.

通过考察头孢氨苄、苯甘氨酸甲酯和7-氨基脱乙酰氧基头孢烷酸(7-ADCA)在ATPS中的分配行为建立了一个含20%PEG 400和12%硫酸镁的ATPS,在此体系中头孢氨苄的分配系数为6.7,苯甘氨酸甲酯的分配系数为1.5,7-ADCA的分配系数为1.2,且青霉素酰化酶的分配系数小於0.01。

The synthesis of nalbuphine hydrochloride from thebaine as starting material was through following processes:oxidation,high-pressure hydrogenation,acetylation,removing methyl of 3-methoxy,hydrolysis,condensation,reduction and finial salification.

以蒂巴因为起始原料,经氧化、高压氢化、乙酰化、氰化、脱3-位甲氧基的甲基、水解、缩合、还原、成盐,合成了盐酸纳布啡,总收率达18。

We expounded the N-alkylation, tricholroacetylation and bromination of pyrrole in chapter two.

第二章,论述了吡咯的N-烷基化、三氯乙酰化及溴代反应。

We have investigated whether the combination of decitabine and a clinically relevant inhibitor of histone deacetylase activity (belinostat, PXD101) can further increase the re-expression of genes epigenetically silenced by DNA methylation and enhance chemo-sensitisation in vivo at well-tolerated doses.

我们研究了地西他滨联合组蛋白去乙酰化酶抑制剂(belinostat,PXD101)是否可以进一步增加DNA甲基化后生沉默基因的重新表达,在耐受性良好的剂量下增加化疗敏感性。

The experimental condition of acetylating method for determining priminary alcohol and secondary alcohol catalyzed by perchloric acid in the medium of analytically pure ethylacetate is proposed.

提出了以高氯酸为催化剂,分析纯乙酸乙酯为介质,乙酰化法测定伯、仲醇的实验条件,实现了对经典方法的改进,简化了操作程

The increasing singlets of protons from acetyl group of product were treated as a reporter of the reaction progress. The reaction yields are calculated by the HR/MAS NMR.

利用四个羟基未保护的Nα-Fmoc氨基酸和七种全乙酰化糖为原料,合成了28个糖基化Nα-Fmoc氨基酸,均用高分辨魔角核磁共振技术定量。

The invention adopts halogen acetylized crosslinked polystyrene resin and hydroxybenzyl alcohol as the raw material, and the solid phase synthesis carrier with hydroxymethyl as the active group is synthesized through the joint catalysis of N, N-dimethyl formamide used as the reaction solvent, inorganic base and phase-transfer catalyst.

本发明采用卤乙酰化交联聚苯乙烯树脂和对羟基苯甲醇为原料,在以N,N-二甲基甲酰胺为反应溶剂、无机碱及相转移催化剂的共同催化下合成了一种以羟甲基为活性基团的固相合成载体。

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