乙酰化

METHODS: A model of T cell activation and proliferation was established by stimulated the cells with Con A.T cells were treated with different concentrations of CPT. The expression of CD69, the early marker of CD3(superscript +) T cell activation, was measured by FACS. The proliferation index was determined by carboxyl fluorescin diacetate succinmidyl ester by flow cytometry. The cell-cycle distribution was analyzed by propidium iodide staining.

以ConA刺激小鼠T淋巴细胞，建立小鼠T淋巴细胞活化、增殖的模型，以不同浓度的CPT作用于该模型，流式细胞术检测T细胞早期活化标志CD69分子的表达；以活体染料羧基荧光素乙酰乙酸染色流式细胞术分析CPT在ConA刺激下小鼠淋巴细胞的增殖相关指数；以碘化丙啶染色流式细胞术分析细胞周期的分布情况。

METHODS: After stimulated with Con A, T cells were treated with different concentrations of TMB-8 alone and its combination with cyclosporine A. The expression of CD69, the early marker of CD3(superscript +) T cell activation, was measured by FACS. The proliferation-related index was determined by carboxyl fluorescin diacetate succinmidyl ester flow cytometry. The cell-cycle distribution was analyzed by propidium iodide staining.

以Con A作为T细胞活化、增殖的刺激剂，以不同浓度的TMB-8及与环孢菌素A联合作用于该系统，用流式细胞术检测T细胞早期活化标志CD69分子的表达；以活体染料羧基荧光素乙酰乙酸染色流式细胞术，分析TMB-8在Con A刺激下小鼠淋巴细胞的增殖相关指数；以碘化丙啶染色分析细胞周期的分布情况。

Manganese oxides supported on SBA-15 Mn(subscript xO/SBA-15 were prepared by incipient wetness impregnation of SBA-15 with furfuryl alcohol solution of manganese acetylacetonate or manganese nitrate followed by removal of the carbon resulted from carbonized FA.

采用溶液浸渍法将乙酰丙酮锰或硝酸锰的糠醇溶液分别灌注到SBA-15的孔道内，一定条件下将糠醇碳化后再将碳烧除，即可得到高度分散的MnO/SBA-15复合催化剂。

Treatment under mild condition with solvent of lower polarity was in favor of keeping the molecular structure and properties such as water-solubility, gelatination, etc. Acetyl groups were partially eliminated when purified by Pb2 method, leading to increased crystallinity and glass temperature, which resulted in losts of water-solubility and gelatinability. Owing to the slight oxidative degradation with H2O2 method, the changes of chain size and some functional groups of KGM molecule led to decrease of viscosity and excessive swelling rate.

采用温和条件及低极性溶剂有利於保持KGM本身的分子结构以及水溶性、凝胶性等性能；而Pb2法由於部分脱去了KGM的乙酰基，导致结晶度变大，玻璃化温度升高，最终失去水溶性和凝胶性；H2O2法则由於对KGM造成了氧化降解，也改变了分子链的大小以及部分基团，从而导致粘度降低以及溶涨速度较快。

Results CsA clearly decreased creatinine clearance and increased urinary excretion of N-acetyl-β-D-glucosaminidase in rats as compared with those in the vehicle group. Morphologic changes consisted of vacuolization of tubular cell, expansion of the interstitium and interstitial fibrosis, hyalinization of afferent arterioles. Severity of the injury was related to the dosage of CsA. Striped interstitial fibrosis and arteriolopathy were more severe in the rats treated with CsA and low-salt diet than with CsA and normal diet.

结果 用CsA的大鼠出现尿量增多、内生肌酐清除率下降、尿N-乙酰-β-D-氨基葡萄糖苷酶排泄增多等；病理上表现为不同程度的细胞浊肿、空泡变性及灶性分布的间质纤维化和小动脉病变，随CsA剂量的增加，病变呈加重趋势；结合低钠饮食，CsA慢性肾毒性病变明显加重。

S: The interface formation and magnetism of Fe, Co overlayer on sulfur passivated GaAs(100) by using CH 3CSNH 2 have been studied with synchrotron radiation photoemission and ferromagnetic resonance.

利用同步辐射和铁磁共振研究了经硫代乙酰胺硫钝化处理的GaAs(1 0 0 )表面生长的Fe、Co超薄膜与衬底的界面形成及磁性。

Results: A 2-AAF/PH model was successfully established to activate the oval cell compartment in rat liver. HOC appeared mainly in periportal areas and could extend into the liver parenchyma. The volume of oval cells was about as big as one forth to one sixth of normal liver cells, with a oval-shaped nucleus and high nuclear/cytoplasm ratio.

结果：以2-乙酰氨基芴加三分之二肝切除术成功建立了大鼠肝卵圆细胞增殖模型，HE染色汇管区可见大量增殖的小圆细胞，并可向肝实质内延伸，免疫组化证实增生细胞OV-6、c-kit、CKl9及AFP染色阳性，而白细胞共同抗原染色阴性。

Paraacetaminophenyl-β-hydroxyethylsulfone can be used as raw material to produce the target product 2-sulfonic-4-(β-sulphatoethyl-sulphone) phenylamine through sulfonationating and hydrolytic reactions.

本文研究了以对乙酰氨基苯基-β-羟乙基砜为原料，经磺化和水解反应，制得产品2-磺酸-4-苯胺的合成工艺，以及2-磺酸-4-乙基砜基硫酸酯苯胺钠盐后处理的最佳操作工艺。

Methods: A brain concussion was produced in rats using a simple pendulum device model. One control (n=12) and six experimental groups were used(n=12 in each group). The cerebral concussion groups were assigned to sacrifice times ranging from 1 day to 24days after injury.A Morris Water Maze memory paradigm was used to assess learning and memory function. Pycnosis degeneration or necrosis neurons in the locus cerebral cortex, dorsal hippocampus, dentate fornix and brainstem reticular formation were observed and counted after brain concussion. Cholinergic neurons in the basal forebrain and brainstem reticular formation were identified and quantitated using choline acetyltransferase.

应用自制单摆式闭合性机械打击装置建立脑震荡大鼠模型；成年SD大鼠随机分为1个对照组(n=12)和6个脑震荡组(即伤后1、2、4、8、16、24d，n=12)；应用Morris水迷宫(Morris Water Maze，MWM)实验评价大鼠的学习记忆功能；用光镜对大鼠的上述脑区的固缩变性坏死细胞进行观察和计数；用免疫组化方法检测基底前脑和脑干网状结构的胆碱乙酰转移酶(cholin acetyltransferase，ChAT)阳性细胞的表达。

With sodium acetate as catalyst, inosine was esterified with acetic anhydride in the yield of 92% to give 2',3',5'-triacetyl inosine, which was treated with pyridine and phosphorus oxychloride to form a pyridinium solution, followed by performing an amination at 40℃ and 0.25~0.30 MPa to achieve adenosine in the yield of 67%.

肌苷在醋酸钠存在下与醋酸酐发生酯化反应以92%的收率得到2'，3'，5'-三乙酰肌苷，其化合物经吡啶和三氯氧磷处理形成吡啶盐溶液，未分离直接在40℃、0.25~0.30 MPa压力下进行氨解反应以67%产率制得腺苷。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。