乙酰化

In young human umbilical vein endothelial cells, human aortic endothelial cells, and human coronary artery endothelial cells, miR-217 induces a premature senescence-like phenotype and leads to an impairment in angiogenesis via inhibition of SirT1 and modulation of FoxO1 (forkhead box O1) and endothelial nitric oxide synthase acetylation.

在婴儿脐静脉内皮细胞、人类主动脉内皮细胞以及冠状动脉内皮细胞中，miR-217可以诱导这些细胞出现一种早衰样表型，进而通过抑制SirT1的表达、调控Fox01以及内皮细胞一氧化氮合酶的乙酰化来损伤新生血管的形成。

BACKGROUND: The choline acetyltransferase is the key synthetic enzyme for acetylcholine, and is the important symbol of the functional activity of the cholinergic system.

背景：胆碱乙酰化转移酶是乙酰胆碱合成的关键酶，是胆碱能神经系统功能活动的重要标志。

HDAC1 has been shown to interact with many key hematopoiesis transcription fators and to influence their activities.

组蛋白去乙酰化酶在血细胞生成和白血病生成中发挥着重要的作用。

Increased hepatic acetylation of histone H3 in the IUGR offspring might be caused by decreased HDAC1 expression in nuclear protein. This may contribute to the transcription change of some genes in the hepar.

IUGR大鼠肝细胞核中HDAC1蛋白表达降低，引起组蛋白H3的乙酰化水平增高，染色质的表观遗传学变化可能是肝脏某些基因转录调控变化的分子基础。

Aim To prepare lower degree of substituted starch acetate with cassava starch as material, acetic anhydride as acetylation reagent, sodium hydroxide as catalyst and sodium sulfate as gelatinization inhibiter.

目的 以木薯淀粉为原料，醋酸酐为乙酰化试剂，NaOH为催化剂，Na2SO4为膨胀抑制剂，制备了低取代度木薯淀粉醋酸酯。

Objective Consequently, by constructing the pcDNA3-HA-hdacl, a HDAC1 eukaryotic expression vector, we were to study the interaction between HDAC1 and ERa and ERB in vitro and the effects of HDAC1 on the ERa and ERB at the protein level. So we can partly reveal the multiplication, differentiation and cancerization of lacteal gland cells.

目的 本文意在通过构建可在真核细胞中表达的重组质粒pcDNA3-HA-hdacl，研究组蛋白去乙酰化酶1(HDAC1)和雌激素受体ERα和ERβ在体外的相互结合作用，以及HDAC1对ERα和ERβ蛋白水平的影响规律，从而在一定角度揭示乳腺细胞的增殖、分化和癌变的过程，为更好地寻找治疗癌症的药物靶标打下基础。

Halogen acetylized crosslinked polystyrene resin is used for replacing commonly used methyl chloride polystyrene resin.

用卤乙酰化聚苯乙烯树脂代替了通常所用的氯甲基聚苯乙烯树脂。

We demonstrate that both the IL-5 mRNA expression and IL-5 protein production were stimulated by TSA and NaBu treatments. Chromatin immunoprecipitation assays showed that treatments of TSA and NaBu caused hyperacetylation of histones H3 and H4 at the IL-5 gene promoter in Jurkat cells, which consequently promoted the exogenous luciferase activity driven by this promoter.

TSA和丁酸钠能促进IL-5基因的mRNA和蛋白的表达水平，并增强该基因启动子所介导的外源荧光素酶报告基因的活性，这一增强作用与两种抑制剂介导的IL-5基因启动子上组蛋白H3和H4的高乙酰化有关。

The degradation kinetics, effect of irradiation on the degree of deacetylation of chitosan and the main chain scission mechanism have been studied.

用 γ射线照射壳聚糖使之发生辐射降解，研究了降解反应的动力学、辐射对壳聚糖脱乙酰化度的影响以及大分子链的断链机理。

Results After induction by VEGF or PDGF for 1 week,most of adherent mononuclear cells became round and small, while few grew into spindle-shaped cells.

结果新鲜脐血分离单个核细胞培养1周后贴壁细胞的EPCs特异的Dil标记乙酰化低密度脂蛋白鉴定为80％阳性。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。