乙酰丙

The results of clinical assessment showed that levosimendan was safe and effective which could improve the prognosis of the patients and kept normal blood kinetics. By improving the reported synthetic route, levosimendan was synthesized from acetanilide via eight steps of reaction.

本论文探索了左西孟旦的合成路线，对文献报道的合成工艺进行了合理有效的改进，以乙酰苯胺为原料，最终经Friedel-Crafts反应，羰基α-位溴代，丙二酸二乙酯缩合，水解，脱羧，环合，拆分及重氮化加成等八步反应合成了左西孟旦。

Ophenyl phenol,ophenyl phenol sodium salt tetrahydrate,7ADCA,2ethyl phenyl hydrazine hydrochloride,2,3dihydrofuran,7ethyl3(2hydroxy ethyl)indole,methyl ester of etodolac; 1,8diethyl1,3,4,9tetrahydropyrano[3.4b] indole1acetic acid methyl ester,5chloro2methoxy benzoic acid,4(2aminoethyl)benzene sulfonamide,5cyano phthalide,phthalhydrazide,9thioxanthenone,n[(1,4benzodioxane2yl)carboxyl]piperazine HCL,2chloro4amino6,7dimethoxyquinazoline,2chloro benzimidazole,1(4fluorobenzyl)2chlorobenzimidazole,2methylthio4pyrimidone,5amino4imidazole carboxamide HCL,6chloro2hexanone,11oxo6.11hydrodibenzothiepin,6,11dihydrodibenzooxepin11one,10,11dihydrodibenzocyclohepten5one;dibenzosuberone,dibenzo cyclohepten5one;dibenzosuberenone,3,5dihydroxy benzoic acid,3,5dihydroxy benzyl alcohol,2mercapto benzimidazole,3,4dihydroxy benzaldehyde,3,4dihydroxy benzonitrile,2amino5chloro benzonitrile,2(4chlorophenoxy)ethyl chloride,2(4chloro phenoxy)tert,butane,ditrimethylol propane;DTMP,2,2bis(4hydroxyphenyl)butane; bisphenol B,1,1'bis(4hydroxyphenyl)cyclohexane;bisphenol Z,tetrabromobisphenolS,3,5ditertbutyl salicylic acid,3,4,5trihydroxy benzoic acid stearyl ester,1,2,4trimethoxybenzene.

华业公司产品：邻苯基苯酚，邻苯基苯酚钠盐，7氨基3去乙酰氧基头孢烷酸，邻乙基苯肼盐酸盐，2，3二氢呋喃，7乙基色氨醇，依托度酸甲酯，5氯2甲氧基苯甲酸，4(2氨乙基)苯磺酰胺，5氰基苯酞，双酮酞嗪，9噻吨酮，N〔(1，4苯并二恶烷2基)羰基〕哌嗪盐酸盐，2氯4氨基6，7一二甲氧基喹唑啉，2氯苯并咪唑，1(4氟苄基)2氯苯并咪唑，2甲硫基4嘧啶酮，5氨基咪唑4 甲酰胺盐酸盐，6氯2已酮，11氧6.11二氢苯并〔b.c〕虑平，11氧代6，11二氢二苯并氧杂卓，10，11二氢二苯并环庚烯5酮，二苯并环庚烯5酮，3，5二羟基苯甲酸，3，5二羟基苯甲醇，2巯基苯并咪唑，3，4二羟基苯甲醛，3，4二羟基苯腈，2氨基5氯苯腈，2(4氯苯氧基)1氯乙烷，2(4氯苯氧基)叔丁烷，双丙烷，2，2二(4羟基苯基)丁烷；双酚B，1，1'双(4羟基苯基)环己烷；双酚Z，2[3，5二溴4(2，3二溴丙氧基)]苯砜，3，5二叔丁基水杨酸，3，4，5三羟基苯甲酸十八烷基脂，1，2，4三甲基氧基苯。

The main products are: organic alcohol, phosphite, chloride, cyclohexyl chloride, Propionyl chloride, such as more than 10 varieties.

主要产品有：有机醇类、亚磷酸、乙酰氯、环已甲酰氯、丙酰氯等十多个品种。

The strongly acidic cation exchange resin catalyzed synthesis of fructone-B by the reaction of ethyl acetoacetate and 1,2-propanediol was studied.

以硫酸高铈铵为催化剂，通过乙酰乙酸乙酯分别与乙二醇和1，2-丙二醇反应合成了苹果酯-A和苹果酯-B，研究了催化剂等有关因素对产品收率的影响。

_6P_2W_(17)VO_(62) catalyst was prepared and characterized by FTIR,and synthesis of fraistone over as-synthesized catalyst from ethyl acetoacetate and 1,2-propylene glycol was investigated.

制备了Dawson型磷钨钒酸铵催化剂，用FT-IR分析方法对催化剂进行了结构表征，并以乙酰乙酸乙酯与1，2-丙二醇为原料催化合成了苹果酯-B。

The condensation of aromatic aldehydes with active methylene compounds like malononitrile, cyanoacetamide and ethyl cyanoacetate has been found to proceed very efficiently at room temperature giving excellent yields, but the condensation of heteroaromatic,α,β-unsaturated and aliphatic aldehydes with active methylene compounds proceeded smoothly in 50~65℃ with good yields and the reactions of aromatic, aliphatic ketones as well as p-phthalaldehyde with malononitrile also proceeded in 75~85℃ with moderate yields.

芳香醛与活泼亚甲基化合物如丙二腈、氰基乙酸乙酯、氰基乙酰胺的缩合在室温下即能顺利进行，获得了很高的收率；而对于杂环芳醛、α，β-不饱和的醛以及脂肪醛与活泼亚甲基化合物的缩合，需在50~65℃下进行，也取得了很高的收率；对于脂肪酮、芳香酮以及二元醛与丙二腈的缩合在75~85℃下也能顺利地进行，获得中等以上的收率。

Employing acetyl chloride as the electrophile afforded the β-acetoxyvinyl-γ-butyrolactone 3 as the product, which provided an experimental evidence to the mechanism involving the palladium enolate intermediate.

使用乙酰氮作为亲电试剂得到了β－乙酰氧基烯基－γ－丁丙酯3，这一结果为烯醇钯中间体的机理提供了一个实验证据。

This thesis consists of four chapters:Chapter 1: Michael addition of chalcones with active methylene compounds such as diethyl malonate, ethyl acetoacetate and nitromethane catalyzed by potassium hydroxide in anhydrous ethanol results Michael adducts in 72-98% yield under ultrasound irradiation in 25-150min.

第一章：研究了超声辐射下，氢氧化钾催化的查耳酮与活泼亚甲基化合物如丙二酸二乙酯、乙酰乙酸乙酯和硝基甲烷的迈克尔反应。

Could keep above 95% in the fixed beds. In order to achieve high stereo-selectivity with yeast, ethyl acetoacetate was used as the model substrate,and a novel approach was proposed to selectively inhibit R-enzymes in yeast before reaction.

以乙酰乙酸乙酯为模型底物，以丙烯酸、乙醚、二甲基亚砜、丙烯酰胺、正己烷等有机溶剂选择性地抑制酵母中R型酶，提高反应立体选择性。

The results showed 3 types of aluminum compound prepared in this paper all had good poison protection effectiveness on such impurities as stannous chloride,lead oxide,sodium hydrogen sulfate,and so on.Moreover,the mechanism of the poison of catalyst was also discussed.

结果表明，合成的3种防中毒剂即防－1、防－2(主要成分为乙酰丙酮合铝)及防－3(主要成分为二乙酰丙酮基异丙氧基铝)对二月桂酸二丁基锡、氯化亚锡、二正丁胺、硫脲、氧化铅及硫酸氢钠等杂质均有较好的防中毒作用；不同防中毒剂对不同杂质的防中毒作用有一定的选择性。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。