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In this thesis, a convenient and efficient synthesis of highly functionalizeddihydropyrido[2,3-d]pyrimidines via a double [5 + 1] annulation strategy startingfrom easily available α-alkenoyl-α-carbamoyl ketene--acetals 1 and cheapreagents (NH4OAc, DMF, and POCl3) has been developed.

本论文探索了一种简便有效的合成高度官能化的二氢吡啶并[2,3-d]嘧啶的方法,此方法由易得的α-乙酰基-α-氨基乙酰基二硫缩烯酮1和便宜的试剂(醋酸铵,二甲基甲酰胺和三氯氧磷)通过两步[5 + 1]加成而实现。

Regulation The key control point of fatty acid synthesis is acetyl CoA carboxylase which catalyzes the formation of malonyl CoA.

调节 脂肪酸合成的关键调空点是乙酰-COA 羧化酶,它催化丙二酰-COA 的合成。乙酰-COA 羧化酶受磷酸化作用而失活。

The activity of pyruvate carboxylase depends on the presence of acetyl CoA so that more oxaloacetate os made when acetyl CoA levels rise.

丙酮酸羧化酶的活性依赖于乙酰-CoA 的存在。因此,当乙酰-CoA,水平上升时,会产生更多的草酰乙酸。

The invention discloses a method for synthesizing acetyl tributyl citrate, which uses tributyl citrate and acetic anhydride as reaction articles, uses naphthalenesulfonic acid methylal as the catalyst during the ester synthesis process, filtering the catalyst from reacted articles after reaction, water-washing, alkaline-washing, distilling the filtrate to obatin acetyl tributyl citrate.

本发明公开了一种合成乙酰柠檬酸三丁酯的方法,它以柠檬酸三丁酯、乙酸酐为反应物,在酯合成过程中用萘磺酸甲缩醛作催化剂,反应结束后,将催化剂从反应后的物料中过滤出来,滤液经水洗、碱洗、蒸馏获得乙酰柠檬酸三丁酯。

ABSTRACT Immobilized penicillin acylase (from E.coli) was used to catalyze 7 phenylacetamido 3 E propenyl cephalosporanic acid hydrolyzation into 7 amino 3 E propenyl cephalosporanic acid. Then, trans APRA was acylated with hydroxyethyl ester of 4 hydroxy D phenylglycine to obtain trans cefprozil.

以7 苯乙酰氨基 3 E 丙烯基 3 头孢菌素 4 羧酸为原料,在青霉素酰化酶作用下,首先酶法水解得到3 E 丙烯基 3 头孢菌素 4 羧酸,过滤固相酶,滤液调pH分离得到反式APRA固体;在青霉素酰化酶作用下,反式APRA再与对羟基苯甘氨酸乙二醇酯缩合,得到反式头孢丙烯;酶法合成所得的产品与进口反式头孢丙烯对照品一致。

hydroxy-2-acetonaphthene was obtained by the hydrolysis of 6-methoxy- 2-acetonaphthene in the presence of HCl (36%) and triethylamine as a catalyst.

摘 要:采用6 甲氧基 2 乙酰萘与浓盐酸在缚酸剂三乙胺存在的条件下进行水解反应制得6 羟基 2 乙酰萘。

In order to synthesize the functional polyquinolines (such as proton conducting polyquinolines and optically active polyquinolines) and investigate structure-property relationships, polyquinolines and polyanthrazolines containing isomeric pyrrole units or 1, 1'-binaphthyl in main chain were synthesized and their properties were studied.

建立了二乙酰吡咯的合成方法;合成并表征了四种二苯酰基-二氨基单体和五种新型的含吡咯基或联萘基的二乙酰基单体;并对部分合成方法进行了改进,简化了实验步骤,提高了产率。

From Cacalia deltophylla (collected from Luqu County, Gansu Province), 22 compounds were isolated, of which 15 compounds have been identified. Among them, two compounds are new. They are named as 3-methyl-4-hydro-8-acetyl-furanonaphth-9-one and 1hydroxy-2-methoxy-3-acetyl-4, 8-dimethyl-5, 8-dihydro-naphthalene.

从采自甘肃省碌曲县的三角叶蟹甲草全草的甲醇提取物的石油醚部分和乙酸乙酯部分中,采用同样方法分离得到22个化合物,鉴定了其中的15个化合物,其中有2个为新化合物,分别命名为3-甲基-4-氢-8-乙酰基-呋喃萘-9-酮(2)和1-羟基-2-甲氧基-3-乙酰基-4,8-二甲基-5,8-二氢-萘(3)。

The main products are as follows: Pharmaceutical Intermediate, Trimethyl Orthoformate , Triethyl Orthoformate, Sodium Methoxide, Power and solution Ethoxide,α-Chloropropionyl Chloride, Acetyl Chloride. Shandong Xinhua Junli Chemical Co.,Ltd.

公司主要产品为医药中间体,原甲酸三甲酯、原甲酸三乙酯、甲醇钠、乙醇钠、α-氯代丙酰氯、乙酰氯,其中原甲酸三甲酯、原甲酸三乙酯是国内唯一采用金属钠法工艺生产的企业。

The invention relates to a synthesis method of N-acetylaminoglucose, which comprises dissolving D-glucosamine hydrochlorate and alcohol at the mass ratio of 2-2.5:100, adjusting the pH value of the solution to 9-10, filtering, taking the filter liquor, mixing and adding acetic anhydride at the 50-60wt% amount of D-glucosamine hydrochlorate, mixing and reacting for 2h, using absolute ethyl alcohol to recrystallizing, filtering and recrystallizing via water, to obtain rod-shape food grade N-acetylaminoglucose.

本发明涉及一种N-乙酰氨基葡萄糖的合成方法。该方法的具体步骤为:将D-葡萄糖胺盐酸盐和乙醇按2~2.5∶100的质量比溶于水中,调节该溶液的pH值为9~10;过滤,取滤液,搅拌下加入乙酸酐,其加入量为原料D-葡萄糖胺盐酸盐量的50~60wt%;搅拌反应2小时后,用无水乙醇进行重结晶;过滤,晶体再用水重结晶,得棒状食品级N-乙酰氨基葡萄糖。

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