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We further examined the effect of change of histone acetylation level in developmentof IVF and NT embryos.

试验还进一步研究了组蛋白乙酰化修饰的变化对早期IVF和核移植胚发育的影响。

However, because acetylation and methylation are driven by cell signals, the epigenome is dynamic, enabling it to respond to the environment.

但是,因为乙酰化和甲基化是通过细胞信号驱动的,表观组是动态的,使得它能够对环境进行反应。

"We looked at the status of the histones and found surprisingly that thymoquinone increased the acetylation process," Dr.

"我们观察组蛋白的状态并且令人惊讶地发现百里香醌能增强乙酰化的过程" Dr。

Genes of histone acetylation, which were changed obviously, were not found.

未发现明显改变的组蛋白乙酰化酶基因。

Therefore,a lower temperature(50℃)and a higher catalyst dosage were adopted in acetylation of high-grade bamboo pulp.

因而我们选择了乙酰化反应采用较低的温度(50℃)相对较高的催化剂用量3%。

This implies that the increase of genetranscripts is because of the positive effect of TSA on acetylation in reprogramming.

在aphicicolin单独处理组中基因的表达水平也没有显著升高,提示基因表达量的显著增加是由于TSA诱导了核重编程过程中组蛋白高度乙酰化而引起的。

Objective:To investigate the relationship between p21WAF1 gene expression and histone acetylation in gastric cancer.

简介: 目的:探讨胃癌组织p21WAF1基因表达与组蛋白乙酰化的关系。方法:利用RT-PCR对53例原发性胃癌的癌组织、癌旁组织和正常胃黏膜的p21WAF1 mRNA表达进行分析;同时对其中p21WAF1 mRNA表达失活或表。。。

Post-translational modification of proteins which contains phosphorylation, acetylation and methylation has attracted more and more attention because of its important role in organism.

蛋白翻译后修饰如磷酸化、乙酰化和甲基化等在生命活动过程中发挥的重要作用使其成为近年来的研究热点。

Based on these data, we proposed a hypothetical model for the involvement of reversible histone acetylation in transcriptional regulation of the p16INK4a gene.

基于这些实验结果,我们推测出可逆的组蛋白乙酰化参与p16INK4a基因的转录调控的模型。

The mechanism by which this occurs may be through competitive inhibition of the acetylation site of cyclooxygenase in the platelet.

这一制度出现的,可通过竞争性抑制乙酰网站化酶与血小板。

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