乙酰

At the same time, adding thymoquinone to pancreatic cancer cells reduced the production and activity of enzymes called histone deacetylases, which remove the acetyl groups from the histone proteins, halting the gene transcription process.

同时，添加百里香醌到胰腺癌细胞能够减少细胞产物并且激活组蛋白脱乙酰基酶，这种酶将从组蛋白中移除乙酰基基团，从而阻止了基因的转录过程。

To elucidate the possible mechanism of differentiation and /or apoptosis in NB4, K562 cells induced by tributyrin, a histone deacetylase inhibitor, the level of acetylated histone H3 was detected by Western blot, p21~ WAF1expression was detected by semi-quantitative RT-PCR.

为了探讨组蛋白去乙酰化酶抑制剂三丁酸甘油酯(tributyrin，TB)诱导NB4、K562白血病细胞分化和凋亡的作用机制，利用Westernblot方法及逆转录聚合酶链反应检测TB作用前后NB4、K562细胞组蛋白H3乙酰化水平以及p21WAF1表达量的改变。

To elucidate the possible mechanism of differentiation and/or apoptosis in NB4, K562 cells induced by tributyrin, a histone deacetylase inhibitor , the level of acetylated histone H3 was detected by Western blot, p21(superscript WAF1) expression was detected by semi-quantitative RT-PCR.

为了探讨组蛋白去乙酰化酶抑制剂三丁酸甘油酯(tributyrin， TB)诱导NB4、K562白血病细胞分化和凋亡的作用机制，利用Western blot方法及逆转录聚合酶链反应检测TB作用前后NB4、K562细胞组蛋白H3乙酰化水平以及p21(上标 WAF1)表达量的改变。

Virtually every enzyme in glycolysis, gluconeogenesis, the tricarboxylic acid cycle, the urea cycle, fatty acid metabolism, and glycogen metabolism was found to be acetylated in human liver tissue.

这一命题中的关键之处在于乙酰化在生物调控中的重要作用。目前蛋白质组学已经发现了上千的被乙酰化的哺乳动物蛋白，中国科学家的这些发现证明了代谢酶。

Cytokines found to have up-regulated in cells were measured in serum and lung tissue of rats exposed to large tidal volume ventilation. For investigating the intracellular pathway of cytokine up-regulation in VILI, exogenous TNF-α or H2O2 was added to culture media of alveolar epithelial cells. Cytokines were then measured. To explore the role of oxidant stress in VILI, N-acetylcysteine, as an anti-oxidant, was used in vitro and in vivo.

我们在体外培养的肺上皮细胞中加入外源性肿瘤坏死因子、过氧化氢或N-乙酰半胱氨酸，观察细胞因子的变化。N-乙酰半胱氨酸亦被投入大鼠呼吸机诱导肺损伤模型，观察用药后细胞因子的变化。

The results show that the properties of different acetylated chitosan membranes have little difference. But they all have high moisture adsorption and transparency, a certain extent permeation and adsorption of bovine serum protein, and can be degradated by lysozyme in vitro.

结果表明乙酰化壳多糖膜的性质随着乙酰化程度的不同性质会有所不同，但它们都有很好的吸水性和透光性，有比较高的结晶性，在体外可被溶菌酶降解，对于小牛血清蛋白有一定的吸附性。

The optimal derivatization condition is reducting reaction 2.5h at 50℃followed by acetylating 2.5h at 90℃.

总结出了单糖衍生化最佳的反应条件为还原温度50℃、还原时间2.5h；乙酰化温度90℃、乙酰化时间2.5h。

The over expression of p33^ING1b can promote the expression of p21^WAP1 which cooperates with p53 to restrain the cell growth by regulating the activity of the acetylating depended pathway.

ING1编码的蛋白通过组蛋白乙酰转移酶和组蛋白去乙酰化酶参与染色质的重塑，在DNA损伤修复方面发挥重要作用。

In this issue, now show that the multisubunit histone acetyltransferase Elongator may regulate migration and branch formation of cortical neurons in the developing mouse brain by acetylating -tubulin.

本文研究显示，在老鼠大脑发育时期，多亚基组蛋白乙酰基转移酶Elongator能通过乙酰化微管蛋白，调控大脑皮层神经分支的迁移与形成。

"Acetylating H3K4 and demethylating H3K9 can actiate a gene; deacetylating H3K4 and methylating H3K9 can silence it," Karpen explains."Multiply modified at arious locations, these histones are a major factor in changing the functions of chromatin, independent of DNA sequence."

&H3K4的乙酰化和H3K9的去甲基化使基因活化；而H3K4去乙酰化和H3K9的甲基化则使基因沉默，& Karpen讲解道，&组蛋白的多部位多重调节是改变染色质功能的主要因素，并与DNA的序列无关&

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。