乙酯基

Orthogonal test was performed to examine the influences of reaction conditions on microwave-assisted synthesis of 2'-oxo-cyclopentanecarboxylic acid ethyl ester from diethyl adipate.

以己二酸二乙酯为原料，在微波辐射下经Dieckmann缩合反应合成2'-羰环戊基甲酸乙酯。

Ethyl 4-[(1-hydroxy-1-methyl)ethyl]-2-propyl-1H-imidazole-5-carboxylate,the key intermediate of Olmesartan ,was synthesized from butanoic acid and o-phenylenediamine via condensation under microwave-irradiation,oxidation,esterification and the Gringard reaction.

用正丁酸与邻苯二胺为原料，在微波照射下缩合成2-丙基苯并咪唑，再氧化开环制得2-丙基咪唑二羧酸，再经酯化、Gringard反应制得抗高血压药物奥美沙坦的关键中间体2-丙基-4-[(1-羟基-1-甲基)乙基]-1H-咪唑-5-羧酸乙酯，总收率32.2%。

The main component was methoxy-ethyl cinnamate with content of 40.96%,next was ethyl cinnamate with content of 23.68%.

主要成分是对甲氧基肉桂酸乙酯，含量为40.96%；其次是肉桂酸乙酯，含量为23.68%。

The study is to synthesize dual-site phase-transfer catalyst, and use it to form tri-liquid phases, and investigate the catalytic benzoylation of 4'-hydroxyacetophenone sodium salt and benzoyl chloride to produce 4-acetylphenyl benzoate in ultrasound-assisted tri-liquid-phase system.

中文摘要本研究在合成双活性基相间转移触媒，并使用该触媒合成三液相系统，并辅以超音波在三液相系统中催化4-乙醯基酚化钠与氯化苯甲醯形成苯甲酸4-乙醯基苯酯的反应。

Mol/L. 3 A study on the ECL of acridinum esters including 10--acridinium-9-carboxyl-phenyl-ester iodinate and 10-methyl-9-(p-formylphenyl)-acrdiniumfluorosulphonate in neutral solution was carried out. It was found both CACPEI and MFPA give strong ECL in KNO〓 solution when an appropriate voltage was applied on Pt electrode.

本文研究了碘化10-乙羧基吖啶-9-羧酸苯酯和对甲酰基苯基-10-甲基吖啶-9-羧酸酯氟磺酸盐的ECL行为，发现在中性KNO〓介质中，这两种吖啶酯都能在一定的电位下产生很强的ECL信号，考察了各种影响因素，确定了发光的最佳条件，探讨了可能的发光机理。

Through condensing o-aminobenzoic acid, ethyl oxalyl chloride and ethylenediamine(or 1,2-propylenediamine), two new ligands N-benzoato-N′-(2- aminoethyl)oxamido(H3oxbe) and N-benzoato-N-(2-amino-2-methylethyl)oxamido(H3oxbt) have been synthesized. Their mononuclear complexes Na·1.5H2O and Na·1.5H2O have also been obtained.

2以邻氨基苯甲酸、草酸乙酯酰氯和乙二胺(或1，2-丙二胺)缩合制得了两种具有不对称草酰胺结构配体N-(2-苯甲酰基)-N&-(2-氨乙基)草酰胺(H3oxbe)和N-(2-苯甲酰基)-N&-(2-氨丙基)草酰胺(H3oxbt)，并得到了它们的单核配合物：Na·1.5H2O和Na·1.5H2O。

In this study, new benzo[l,2,3]thiadiazole derivatives were designed according to relationship of structure and efficacy. The 9 novel compounds were synsthesized with following reactions. The chlorine atom in 2-chloro-3,5-dinitro-benzoic acid as beginning raw material was substituted by 2-methylpropane-2-thiol, esterified then with bromoethane, reduced by iron powder and cyclized to obtain ethyl benzo[l,2,3]thiadiazole-7 after diazonation reation.

本论文根据苯并噻二唑诱导剂的构效关系设计了新的苯并噻二唑的结构，并合成了9个未见文献报道的化合物，合成步骤如下：采用2-氯-3，5-二硝基苯甲酸为起始原料，苯环上的氯原子被叔丁基硫醇置换，羧酸由溴乙烷酯化，硝基由铁粉还原，随后经重氮化关环生成苯并[1，2，3]噻二唑-7-羧酸乙酯。

D-Pantothenyl alcohol, also called ortho-vitamin 85, is an important nutrition suppled substance. It has been widely applied in the field such as medicine, cosmetic, foodstuff, feed additive, and so on. The preparation of D-pantothenyl alcohol and the optimization of key factor are discussed mainly in this paper. It mainly includes three section.In the first section, with formaldehyde, isobutyl aldehyde and diethyl oxalate as the starting materials, D-pantolactone is prepared via three steps including condensation, catalytic hydrogenation and physical resolution. The specific rotatory power of the product is consistent with imported product.

D-泛醇，俗称原维生素B_5，属维生素B旋类营养增补剂，广泛应用于医药、化妆品、食品、饲料等领域，本文着重探讨了其制备及关键因素的优化，主要内容可分三部分：第一是D-泛内酯的制备，先以甲醛、异丁醛和草酸二乙酯为起始原料合成酮基泛内酯，再经催化氢化得到DL-泛内酯，然后通过物理拆分获得D-泛内酯，得到产物的比旋光度与进口产品基本一致。

Several glycosyl phosphate and phosphonates, as inhibitors of AGPase, were synthesized.In the synthesis of β〓-6 linked oligosaccharide phosphonates, A new method was developedfor preparation of 〓,6-〓-di-acetyl-2,3,4-〓-tri-benzyl-D-hexoses by acetylation of benzylatedmethyl glycosides in high yield under the conditions of 〓 and cat.〓.

合成了一些磷酸酯及其类似物作为嗜热AGPase的抑制剂，在研究β 1-6连接的寡糖膦酸酯的合成中，发现了制备1，6-〓-二乙酰基-苄基保护糖的新方法：苄基保护的糖苷在醋酐和催化量的硫酸作用下，在0℃反应进行7-10 min，可以选择性、高收率地得到此化合物。

In this dissertation, preparation of polysubstituted ethene and heterocyclic compounds based on 2-hydroxyalkyl phenyl selenides andα-phenylselenopropionic acid reagents were further investigated as follow: Firstly, O-ethyl-O-vinyl phosphonates were prepared in a one-pot, two-step transformation by Mitsunobu reaction of 2-hydroxyalkyl phenyl selenides with monoethyl esters of phosphonic acid in the presence of diethyl azodicarboxylate and triphenyl phosphine (PPh3) followed by oxidation-eliminatio...

中文摘要：本文主要进一步探索了2-羟基烷基苯基硒醚、α-苯硒基丙酸试剂在制备多取代乙烯和杂环化合物反应中的应用，具体研究内容和结果如下：一、在偶氮二羧酸乙酯和三苯膦(PPh3)存在下，苯基-2-羟基烷基硒醚和O-乙基膦酸单酯发生Mitsunobu反应，无需分离和纯化反应中间体，直接使用30 %的双氧水进行氧化-消除反应，提供了&两步、一锅&合成O-乙基-O-乙烯基膦酸酯的新方法，该方法反应条件温和，操作简便，产物收率良好(76-82 %)。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。