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To further investigate whether cyclin A played as a key molecular in cell proliferation, HL-60 cells were exposed to different concentrations of hexamethylene bisacetamide.

为了进一步研究cyclin A在白血病细胞增殖中的作用,用在体内、体外均有抗肿瘤作用的六亚甲基二乙酰胺在体外抑制白血病细胞系HL-60增殖,并诱导其分化。

To further investigate their roles in cell proliferation apoptosis and differentiation, three human leukemia cell lines (K562, U937 and HL60) exposed to various concentration of hexamethylene bisacetamide, a potent inducer of differentiation of transformed cells both in vivo and in vitro, were used as an in vitro model for the study of cell proliferation, differentiation and apoptosis.

为了进一步研究cyclin A和p21在白血病细胞增殖,分化,凋亡中的作用,我们用在体内,外均有抗肿瘤作用的药物六亚甲基二乙酰胺在体外抑制白血病细胞株K562,U937和HL60增殖,诱导其分化,成功地建立了与药物干预浓度呈剂量-效应关系的,具有不同增殖,分化,凋亡状况的实验细胞模型。

In this paper,we used hexamethylene bisacetamide as a inducer to induce human mucoepidermoid carcinoma cell line MEC-1 cells to differentiate in vitro and vivo.The nucleolus organizer regions was investigated by means of the argyrophil technique.

本实验以六亚甲基二乙酰胺作为分化诱导剂,对涎腺粘液表皮样癌MEC-1细胞进行了体内外诱导,并通过银染技术对对照组和HMBA诱导组癌细胞核内核仁组成区的数目、大小及分布特征进行了观察。

Alanine, glycine and glutamine, and present weak resonances of creatinine also; diabetes mellitus patients show hyperglycorrhachia and strong resonances for ketone bodies and glycine; patients with benign prostatic hypertrophy or urethral stone have high levels of creatinine; the genital tumor females can be distinguished with low pyruvate levels on the bases of /sup 1/H-NMR spectra.

以下乃是由上述样品族群之氢光谱所得之结论;孕妇的脑脊髓液具有低浓度的脊髓糖;胺基酸(如丙氨酸;麸氨酸和甘氨酸)和肌酸酐;有酮体生成,糖尿病患的脊髓液在氢核光谱显示高浓度的脊髓糖,另外有丙酮酸;乙醯乙酸盐和甘氨酸的强烈共振讯号,而具摄护腺肥大症或是尿道结石的病患,具有高浓度的肌酸酐在其CSF的氢光谱中。

By analyzing and researching the corrosion resistant mechanism of adsorption typal acidification corrosion inhibitor, taking single equational experimental method, making use of mannich reaction and using the hydrochloric acid as catalyst and the ethyl alcohol absolute as solvent, the new acidification corrosion inhibitor HZ-1 is synthesed by formaldehyde、hypnone、aromatic amines in the present research of this thesis.

本文通过对吸附型酸液缓蚀剂缓蚀机理的分析和研究,利用单因素实验方法,采用曼尼希反应,以盐酸为催化剂,无水乙醇为溶剂,用甲醛、苯乙酮、芳香多胺合成了新型酸化缓蚀剂HZ-1。

Methods: The rats were injected with thioacetamide 600mg/kg twice at same time for two days to induce the model of acute hepatic failure rat except the normal group injected with the normal saline hypodermically.

按600mg/kg的剂量经皮下注射硫代乙酰胺1次,24小时后按相同剂量重复注射1次,造成大鼠急性肝衰竭模型,于实验前3天至实验结束分别给予各组大鼠生理盐水,不同剂量丹黄方及促肝细胞生长素,观察造模后48小时内大鼠病死率,并于造模48小时后经腹主动脉采血测定ALT、AST、TBil、TNF-α、IL-6,取肝组织作病检。

An ingestible mollusc poison contains a simple metal compound, an activity enhancing additive such as ethylene diamine disuccinic acid and derivatives thereof, and a carrier material edible to molluscs.

一种可吞食的软体动物毒药,它含有简单金属化合物,增强活性的添加剂诸如乙二胺二琥珀酸及其衍生物,和软体动物可食用的载体材料。

The interatomic distances are calculated and discussed.

因此,乙二胺四乙酸只表现出二元酸的性质,分子的结构式应写成

Purpose To study the therapeutic dose of 153Sm-EDTMP for interradiation.

目的 探讨153Sm-乙二胺四甲撑膦酸内照射治疗剂量。

Results] LD50 for acephate by intragastric administration is 823 mg/kg in rats.

结果]乙酰甲胺磷大鼠经口LD50为823 mg/kg。

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