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乙胺

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With toluene two isocyanogen diethylene glycol dinitrate, the polyester or the polyether dihydroxy alcohol, two methylol propionic acid, the triethylamine, the ethylene diamine and so on are raw materials, uses the prepolymer dispersion method, has prepared a series of anion river character polyurethane emulsion.

用甲苯二异氰酸酯、聚酯或聚醚二元醇、二羟甲基丙酸、三乙胺、乙二胺等为原料,采用预聚物分散法,制备了一系列的阴离子水性聚氨酯乳液。

The results of RT-PCR show that zebrafish treaded TAA 10th day made adipogenetic and lipogenetic up-regulated on the 3th and 5th day, because on TAA treated control Data show that lipogenetic gene would up-regulate at 9th day, so overexpression of PPARγ enhance TAA induced fatty liver.

反转录聚合链反应结果显示转殖PPARγ经TAA处理十天后,在第三有提高的现象,但是从硫乙胺处理控制组的结果显示第9天时,脂肪生成相关基因才会上升,故PPARγ的表现加强了硫乙胺诱导脂肪肝的形成过程。

The chromatographic conditions were as followed: C8 column, 0.045 mol/L ammonium phosphate monobasic solution∶acetonitrile (2∶1)(adjusted to pH7.35 with triethylamine) as mobile phase, temperature: 40℃, the flow rate: 1.0 ml/min, detection wavelength: 210nm.

采用C8柱,以0.045mol/L磷酸二氢胺溶液∶乙腈(2∶1)(用三乙胺调pH至7.35)为流动相,流速1ml/min,检测波长210nm,柱温40℃。

The chromatographic conditions were as followed: C8 column, 0.045 mol/L ammonium phosphate monobasic solution∶acetonitrile (2∶1)(adjusted to pH7.35 with triethylamine) as mobile phase, temperature: 40℃, the flow rate: 1.0 ml/min, detection wavelength: 210nm.

采用C8柱,以0.045mol/L磷酸二氢胺溶液∶乙腈(2∶1)(用三乙胺调pH至7.35)为流动相,流速1ml/min,检测波长210nm,柱温40℃。结果阿奇霉素的线性范围为50.3~1006μg/ml,平均回收率100.1%,r=1.0000,RSD=0.8%(n=9)。

The chromatographic conditions were as followed: C8 column, 0.045 mol/L ammonium phosphate monobasic solution∶acetonitrile (2∶1)(adjusted to pH7.35 with triethylamine) as mobile phase, temperature: 40℃, the flow rate: 1.0 ml/min, detection wavelength: 210nm.

采用C8柱,以0.045mol/L磷酸二氢胺溶液∶乙腈(2∶1)(用三乙胺调pH至7.35)为流动相,流速1ml/min,检测波长210nm,柱温40℃。结果阿奇霉素的线范围为50.3~1006μg/ml,平均回收率100.1%,r=1.0000,RSD=0.8%(n=9)。

Cellulose benzoate,the degree of substitution of which was calculated from the content of C determined by element analysis,was prepared from microcrystalline celluloseand benzoyl chloride under heterogeneous condition and characterized by FT-IR and~1H-NMR.

研究了微晶纤维素和苯甲酰氯在多相条件下合成制备纤维素苯甲酸酯的反应,通过元素分析所得碳的质量百分含量计算了产物的取代度,并系统研究了吡啶与N,N-二甲基乙酰胺或与三乙胺混合反应溶剂、苯甲酰氯与纤维素羟基的摩尔比r、反应温度和反应时间对D S的影响,用FT-IR和1H-NM R对产物进行了表征。

Thanks for doctor Jiang's remind. Clindamycin +Pyrimethamine or Dapsone+ Pyrimethamine is for Toxoplasma .

对不起,谢谢江医生的提醒,克林霉素+乙胺嘧啶不是伯安奎(克林霉素+伯安奎给PCP的)或氨苯砜+乙胺嘧啶。

Ethambutol is the key intermediate of ethambutol hydrochloride which is used as a chiral antituberculosis agent.

对手性抗结核药物盐酸乙胺丁醇的关键中间体———乙胺丁醇的合成进行了系统研究。

Conclusions]There is a significant difference at protein level between untreated and ethambutol treated mc2155 cells. It suggests that the differential expression analysis of proteomes may be useful for further study on microbiostatic mechanism of ethambutol and search for new targets toward anti-TB drug development.

结论]乙胺丁醇处理前后耻垢分枝杆菌mc2155细胞的蛋白质组具有差异,这种蛋白质组的差异分析有助于进一步研究乙胺丁醇抑制分枝杆菌生长的作用机制并为寻找新的抗结核药物作用靶标奠定基础。

[Objective]To investigate the microbiostatic mechanism of ethambutol, proteomic methods were used to find differential expression proteins in Mycobacterium smegmatis mc2155 cells treated with ethambutol.

[目的]利用蛋白质组学方法,识别乙胺丁醇处理前后耻垢分枝杆菌mc2155细胞后差异表达的蛋白质,为进一步探讨乙胺丁醇抑制分枝杆菌生长的作用机制及寻找新的抗结核药物作用靶标奠定基础。

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