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A plausible process of this reaction is as following: Aldehyde was in equilibrium with the enol form, aldehyde reacted with aniline catalyzed by 2,2,2-trichloroacetic acid to afford imine, the generated imine immediately reacted with enol to form intermediate via intramolecular cyclization.

我们发现一分子芳基叠氮和一分子三苯基磷反应生成一分子磷亚胺,后者与由两分子取代的苯氧乙酰氯原位生成的烯酮反应生成4-亚烷基-β-烷基-内酰胺,其串联过程涉及烯酮亚胺的形成及其与烯酮的[2+2]的环加成反应。

Three methods for the preparation of 1,2,4-trizolone~5 are provided. 22 compounds are prepared. 3, 4-disubstituted 1,2,4-trizolone-5 is prepared by reacting amide with ethyl hydrazine-fornate at 110癈 for 3h in the presence of phosphorus oxychloride, following neutralization and cyclization reaction, giving to 74.5 % yields,which is 30% more than the literature value.

以三氯氧磷为缩合剂,使酰胺和肼基甲酸乙酯在110℃反应3h,经碱中和、环化反应,合成3,4-二取代-1,2,4-三唑酮-5,两步反应总产率达74.5%,与文献报道值相比,高出了30%以上,在三唑酮类衍生物的合成方法中具有很大的突破性。

The results of this reseach showed that administration of SF intracolonically had protective effect on the colon injury in the rat model of colitis induced by acetic acid enema, which was probably due to the mechanism of antioxidation, inhibition ofarachidonic acid metabolis and platelets activation, administration of SF intracolonically also showed protective effect on the colon injury in the rat model of colitis induced by trinitrobenzene sulfonic acid and ethanol, which was probably due to antioxidation and inhibition of macrophages activation.

实验研究表明,大鼠分别经乙酸、TNBS和乙醇处理后均出现典型的结肠炎症状,给药后分别评价结肠粘膜损伤指标、结肠组织病理变化,检测结肠组织炎症指标、结肠组织氧化损伤指标及主要炎性细胞因子改变;实验结果:阿魏酸钠对大鼠乙酸性结肠炎结肠粘膜损伤具有缓解保护作用,其机制可能与直接抑制炎症结肠粘膜花生四烯酸代谢过度,抑制血小板活化,清除大量氧自由基有关;阿魏酸钠对大鼠TNBS性结肠炎粘膜免疫损伤亦具有缓解保护作用,其机制可能与抗氧化,抑制结肠巨噬细胞活化有关。

The swelling properties of epoxy vinyl ester resin/2-hydroxyethyl methacrylate copolymeric hydrogels were investigated.

该文研究了酚醛环氧型乙烯基酯树脂/甲基丙烯酸-β-羟乙酯共聚水凝胶的溶胀性质。

A series of hydrogels based on macromonomer novolac epoxy vinyl ester resin and hydrophilic-2-hydroxyethyl methacrylate were synthesized by bulk copolymerization.

采用大分子单体酚醛环氧型乙烯基酯树脂与亲水性单体甲基丙烯酸-β-羟乙酯为原料,以本体聚合方法制备了一系列新型水凝胶。

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This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。

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双标记神经干细胞的增殖、分化活力与未标记神经干细胞相比无改变。