乙型肝炎

Objective To explore and discuss the prevention and treatment of hepatitis B virus reinfection after liver transplantation for severe hepatitis B.

目的 探讨重型乙型肝炎肝移植术后乙型肝炎病毒(hepatitis B virus， HBV)再感染的防治。

Methods Two groups were randomly set:control roup in which 50 cases were only treated by medicines,and treatment group in which 56 cases were additionally treated by the hepatic equipment.

将慢性病毒性乙型肝炎患者106例，随机分为治疗组56例及观察组50例，观察肝病治疗仪治疗对慢性病毒性乙型肝炎患者的肝功能及免疫功能的影响。

Objective To study the relationship of serum Hepatitis B virus DNA and immunological markers for type B Hepatitis.

目的 探讨血清中乙型肝炎病毒核酸含量和其免疫标志物的关系，其在乙型病毒性肝炎临床诊治和预后中的应用评价。

Objective\ To study the infection state of the HBV DNA in peripheral blood mononuclear cells and serum of patients with chronic hepatitis B and its clinical significance.

1目的探讨慢性乙型肝炎病人外周血单个核细胞乙型肝炎病毒 DNA和血清 HBVDNA的感染情况及其临床意义。

Objective:in order to compare the curative effects of using lamirudine and thymosin together with using thymosin only to the paients of chronic hepatitis b.methods:we had chosen 27 medical cases of chronic hepatitis b,which were divided into two groups:15 cases asone group,and 12 cases as the other group.let group a take 100 mglamirudine orally,qd,with half a year as a period of treatment.at the same time givethe patients injections of 100 mg thymosin,qd,for a month.to group b was only takenlamirudine.alt,tbil,the indicators of the virosis of hepatitis b (hbsag,hbeag,hbv-dna)were observed as quatos.results: at the end of the treatment, the rates that groupa and group b made hbsag transform into negative were respectively 26.67% and 16.67%(p＞0.05);hbeag:33.33%,8.33%;hbv-dna:53.33%,33.33%(p＞0.05).conclusion:combining thymic peptide with 3tc to treat chronic type b hepatitis, thymic peptide will not only promote b-cell to mature and transformation, but also to keep the subpopulation of t-cell in immune system in balance, which can enhance the reaction of matured t-cell to the antigen or other stimulus.

目的：比较拉米夫定（3tc）与胸腺肽联用和单用拉米夫定治疗慢性乙型肝炎的疗效。方法：选择慢性乙型肝炎患者27例，分为联合组15例和拉米夫定组12例；联合组用拉米夫定100 mg，口服，qd，疗程半年，合并用胸腺肽100 mg，静滴，qd，疗程1个月。拉米夫定组单用拉米夫定。以谷丙转氨酶、血清胆红素、乙肝病毒标志物(hbsag，hbeag，hbv-dna)为观察指标，比较不同治疗方案对指标的影响。结果：治疗结束时联合组与拉米夫定组对慢性乙肝患者血清hbsag阴转率分别是26.67％和16.67％(p＞0.05)；hbeag阴转率分别是33.33％和8.33％(p＞0.05)；hbv-dna阴转率分别是53.33％和33.33％(p＞0.05)。结论：胸腺肽联合3tc治疗慢乙肝，胸腺肽具有促进t淋巴细胞的成熟和转化，并维持免疫系统各t淋巴细胞亚群间的平衡作用，能增强成熟t淋巴细胞对抗原或其他刺激的反应。

MethodsThe frequency of CD4+CD25+T cells in the peripheral blood mononuclear cells from 30 cases of severe hepatitis B, 20 cases of chronic hepatitis B, 20 cases of chronic asymptomatic HBV carriers and 10 healthy controls were determined by flow cytometry and their serum HBV DNA levels were detected by Quantitative Fluorogenic PCR.

方法采用流式细胞仪检测30例重型乙型肝炎患者、20例慢性乙型肝炎患者、20例无症状乙肝病毒携带者和10例健康的外周血CD4+CD25+调节性T细胞（CD4+CD25+Treg）的水平，并应用荧光定量PCR方法测定上述研究对象血中HBV DNA滴度。

The recombi- nant hepatitis B virus polymerase expressed in cells infected by recombinant baculovirus was determined by SDS-PAGE, The hepatitis B virus polymerase was expressed in insect cells at high level.

结论利用杆状病毒表达系统，构建的重组杆状病毒在昆虫细胞中高效表达乙型肝炎病毒多聚酶，为进一步的乙型肝炎病毒多聚酶的体外功能研究奠定了基础。

Objective To explore the relationship between the quantities of HBV and the models of serologic markers.

目的 对乙型肝炎病毒DNA载量与HBV血清标志的关系进行研究，探讨乙型肝炎病毒载量与机体免疫反应的关系，为抗病毒治疗提供科学依据。

Hepatitis B Virus ; HBV Infection ; Infection pattern ; Drugging ; Male

乙型肝炎病毒；乙型肝炎病毒感染；感染模式；吸毒；男性

Object to investigate the diagnosis value of Fibro Index and APRI and its consociation in hepatitis B induced hepatic fibrosis,To develop noninvasive method for detecting the severity and activity of the patients with hepatitis B induced hepatic fibrosis.

中文摘要目的：通过分析Fibro Index和APRI及其联合应用对慢性乙型肝炎患者肝纤维化的诊断价值，从而为临床评估慢性乙型肝炎肝纤维化提供简单、可靠的无创性诊断方法。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。