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Areas of hypoxic tumour tissue are known to be resistant to treatment and are associated with a poor clinical prognosis.

我们知道,乏氧的肿瘤组织区域对治疗往往耐受,且与临床预后不良有关。

Objective: To determine the potency of QN-2013, a derivative of quinoxaline 1,4-N-oxide, as a hypoxia-selective cytotoxin or a radiosensitizer.

目的:检验和评价喹喔啉双氮氧化物衍生物QN-2013的选择性乏氧细胞毒性和放射增敏作用。

Methods The human pancreatic cancer Panc-1 cells were exposed to a single fraction of high-doseγ-ray radiation either with CMNa or under hypoxic condition. The percentage of dead cells was detected with a multiwell plated reader, and fluorescence intensities of propidium iodide were measured before and after digitonin treatment.

在乏氧和加不同浓度CMNa环境下对体外培养的人胰腺癌Panc-1细胞进行单次大剂量的γ射线照射,通过微孔板荧光酶标仪检测细胞死亡率来研究放射增敏作用。

Many studies have indicated that hypoxia is a common phenomenon in animal and human solid tumors.

许多研究表明,乏氧是动物和人实体瘤中的一种普遍现象。

Objective To investigate the effects of glycodidazolum natrium on pancreatic cancer cells under hypoxic condition.

目的 研究甘氨双唑钠在乏氧环境下对人胰腺癌Panc-1细胞的放射增敏效果。

To observe the effect of HIF-lα on hypoxia-activatad angiogenesis regulation pathway in esophageal squamous cellcarci- noma.

目的观察体外乏氧培养条件下食管鳞癌细胞系EC9706中HIF-1α和VEGF的表达,探讨HIF-1α在低氧条件下对食管鳞癌血管生成的调控作用。

OBJECTIVE To discuss the inhibitive activity of proteinase of hypoxic cell s radiosensitizer .

探讨乏氧细胞放射增敏剂的蛋白酶抑制活性。

The selective radiosensitive effect of CMNa on hypoxia was time-dependent.

CMNa在乏氧环境下的选择性增敏作用具有时间相关性。

[Purpose] To monitor the hypoxic change of gastric cancer during metronomic chemotherapy with paclitaxel-liposomes by the hypoxia imaging.

作者:郑勇斌,童仕伦,赫杰,马书进[目的]利用乏氧显像监测紫杉醇脂质体节奏性化疗过程中胃癌的乏氧变化。

Our research included four parts: design and synthesis of amine oximes and other compounds as ligands, label them with 〓Tc〓, assessment of their biological activities in vitro and in vivo, and preparation of 〓 kit for clinic use.

研究工作主要包括合成作为配体的〓及其类似物,制备其〓Tc〓标记物,进行乏氧细胞实验和荷瘤动物实验,考察它们在肿瘤细胞中的吸收与体系乏氧的关系,以及在不同荷瘤动物模型中的放射性分布和显像情况。

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With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务,乐队在现实中树立了重要的影响。

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不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐,因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。

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关闭眼睛,深呼吸,一切不再是梦想,犹如。。。。。。