主要产物

Investigation of major metabolic pathways of SFZ-47 in animals The metabolites of SFZ-47 in rabbit urine following oral administration were separated and detected with HPLC and LC-MS methods. On the basis of the chromatographic behavior and mass spectra of the metabolites as well as biotransformation pathways of drugs with the partial structure of SFZ-47, the hydroxylic derivative 4-(3H-1, 2- dihydro-1-pyrrolizinone-2-methylamino benzyl alcohol and the carboxylic derivative 4-(3H-1, 2-dihydro-1-pyrrolizinone-2-methylamino benzoic acid of SFZ-47 were proposed as two potential metabolites and were synthesized.

在动物体内主要代谢途径的确定用HPLC和LC-MS对家兔口服SFZ-47后尿中的代谢物进行了分离、检测，根据代谢产物的色谱和质谱行为以及与SFZ-47有类似结构部分的其它药物的代谢途径，推测其羟基衍生物[4-（3H-1，2-二氢-1-吡咯里嗪酮-2-甲基胺基）苯甲醇]与羧基衍生物[4-（3H-1，2-二氢-1-吡咯里嗪酮-2-甲基胺基）苯甲酸]是两种可能的代谢产物，遂用化学方法合成了这两种衍生物。

There are two main factors govern the diverse structures of complexes 15 and 16:(1) reaction time and temperature, that is to say, complex 15 is kinetically stable complex, while complex 16 is thermally stable one.

它们结构的不同主要有两个方面的影响因素：一、反应的时间和温度的影响，即晶体15是动力学稳定的产物，晶体16是热力学稳定的产物；二、溶液pH值的影响，即晶体15在pH值较大(≈6)的情况下析出，而晶体16在pH值较小(≈4)的条件下析出。

High pressure and temperature experiment show that lamprophyric melt and orthophyric melt mix with each other under high pressure and seperate under low-pressure.

结合哀牢山断裂带富碱侵入岩的地质地球化学资料，论证了煌斑岩与富碱侵入岩为富集地幔不同部分熔融程度的产物；高温高压实验表明，煌斑岩熔体和花岗斑岩熔体在高压条件下发生混合，低压条件下出班分离，加上有关的地球化学判别，推测岩浆混合作用是本区煌斑岩与花岗斑岩(富碱侵入岩母岩浆同化分异结晶作用的产物)密切共生的主要因素。

The results indicated isoprene was soon consumed under the condition of excess ozone. During the reaction, the major carbonyl products formed were methyl vinyl ketone, methacrolein, methylglyoxal, and formaldehyde. Formic acid, CO and CO2 were also among the products.

在反应温度(294±2)K，压力为1.01×10^5Pa空气，O3过量的条件下，异戊二烯很快反应完全，反应中生成的羰基产物主要包括甲基丙烯醛、甲基乙烯基酮、丙酮醛和甲醛；产物中还包括甲酸、一氧化碳和二氧化碳。

The main gluconeogenic precursor in kidney is thought to be lactate; however, less is emphasized enantiomerically. L-lactate is a glycolysis end-product, but D-lactate is formed after detoxification of methylglyoxal, which is the main source of advanced glycation end-products.

乳酸为肾脏糖质新生的主要来源，其含有一不对称碳，故具有D-、L-乳酸两种镜相异构物，而D-、L-乳酸两者之生成相当不同，L-乳酸是糖解作用之终产物，D-乳酸为体内一醣化终产物(advanced glycation end-products)─甲基乙二醛进行去毒化反应所生成，目前缺乏对乳酸镜像异构物与肾脏糖质新生间相关的探讨。

The analytical results have shown that p ro ducts mainly consisted of some monosubstituted, disubstituted and a few trisub stituted naphthalenes. Except the low activity of HZSM-5 catalyst, all other z eolite catalysts have higher activity. HY and Hβ catalytic activities were the highest, and their naphthalene conversions attained to 79.12 and 55.79 percent respectively, but their selectivities for 2-isopropylnaphthalene, 2,6-diisopropylnaphthalene(2,6-DIPN) and 2,7-diisopropylnaphthalene ( 2,7-DIPN) were too low. ZM catalysts had good activity and much better selecti vity, especially for ZM4-3, of which its 2,6-DIPN/2,7-DIPN ratio was 2.97. Th er efore, some zeolite catalysts are recommended for shape selective isopropylat ion of coal tar naphthalene.

研究结果表明，煤焦油萘异丙基化产物主要由一取代萘、二取代萘以及少量三取代萘组成；除HZSM-5活性较低以外，其它催化剂均有较高的反应活性，其中HY和Hβ反应活性最高，萘转化率分别达75.15％和55.96％，但β位产物的选择性较差；ZM类催化剂既有一定的活性，又有较高的β选择性，是萘择形异丙基化反应理想的备选催化剂。

The measurement of nicotine and its major metabolites cotinine and trans-3 -hydroxicotinine together with other minor metabolites (e.g., cotinine N-oxide, cotinine, and trans-3 -hydroxicotinine glucuronides) in conventional and nonconventional biological matrices has been used as a biomarker to assess the exposure to environmental tobacco smoke during childhood.

常规和非常规性生物基质内尼古丁、尼古丁主要代谢产物可替宁和反式-3-羟基可替宁及其他代谢产物（可替宁N-氧化物，可替宁和反式-3 –羟基可替宁葡萄糖苷酸）的检测可作为评价儿童期环境烟草烟雾暴露的一个生物标志物。

By GC-MS analysis, the liquefied products contained oligomers of polyhydric alcohols, carboxylic acids and their esters because of oxidation and esterification of polyhydric alcohols and the decomposed cornstalk components.

GC-MS分析表明，液化产物中主要含有多元醇的低聚合体，以及多元醇和玉米秸秆降解产物的氧化和酯化反应产生的羧酸及其酯。

The lifetime of nylon 1010 and nylon 1010/POSS composites decreased with increasing temperature.

热重-红外联用分析表明尼龙1010在氮气气氛下的降解产物主要为小分子的低聚物，POSS并不改变尼龙1010降解产物的组成。

On the basis of an integrated analysis of the geochemical features of these volcanic rock associations,this paper concludes that thebasalts originated mainly from interaction between mantle-derived magma and low-crustal materials, and rhyolitic volcanic rocks resulted from thermal and chemical interaction between basaltic magma and the upper part of crustal materials.Basalts and rhyolites in different cycles have different source regions,and they are products of multiperiodic pulsive layer partial melting.

根据对火山岩地球化学特征的综合分析表明，玄武岩主要为幔源岩浆与下部地壳岩石相互作用的产物，而流纹岩则为玄武岩浆与上部地壳物质进行热及成分交换的结果，不同旋回的玄武岩和流纹岩有不同的源区，为多次脉动分层部分熔融的产物。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。