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These women, ages 61, 72 and 74 years, receiving long-term pergolide therapy for Parkinson's disease or restless legs syndrome, had valvular abnormalities strikingly similar to those induced by fenfluramine, ergot derivatives, or carcinoid. All three had severe, unexplained tricuspid regurgitation; two had predominantly right-sided congestive heart failure; and two had moderate aortic and mitral valve regurgitation. Histology revealed surface fibroproliferative lesions with preserved underlying valve architecture. Carcinoid was excluded, and none of the patients had taken anorectic drugs or ergots other than pergolide.

这3位妇女年龄分别为61、72及74岁,都长期服用pergolide来治疗帕金森氏症或睡眠脚动症,而且也都有不明原因的严重三尖瓣闭锁不全,就像因fenfluramine、麦角衍生物,或类癌肿瘤所引起的瓣膜异常情形一样;其中2位主要有右心衰竭,2位有中度的主动脉及二尖瓣的闭锁不全,组织学检查显现表面有纤维增生性的损伤,但瓣膜的结构仍然还在;类癌是被排除在外的,而且这3位妇女除了pergolide之外,都不曾服用过厌食剂或麦角类药物。

Objective To compare the relationship between measurement of the time constantly derived from aortic regurgitant velocity spectra and catheter derived time constant, and to evaluate the effects of hemodynamic flow states and regurgitant volumes on the Tau AR.

目的 对比研究由主动脉返流频谱得到的时间常数Tau和心导管根据左室压力曲线得到的时间常数的相关性,评估血流动力学参数和返流容积对Tau-AR的影响。

L-1 (10-7mol . L-1) noradrenaline induced contraction of rat aortic strip was taken as criterion. Compound I5 was shown to be a potent potassium channel activator. Compound II8 exhibited calcium antagonistic activity and showed potent vasodilating activity.

引起的大鼠主动脉条收缩有较好的抑制作用,其中化合物 I5的钾离子开放活性与尼可地尔相当,化合物 II8显示有钙离子通道拮抗活性,并有较强的扩血管活性。

Our results indicated that (1)SO_2 derivatives could dose-dependently relax the isolated aorta rings with or without endothelium precontracted by NE, no difference was found for the rings with and without endothelium;(2)Levels of cAMP and 6-Keto(PGI_2) in isolated aortic rings were increased by SO_2 derivatives in a dose-dependent way, which were independent of endothelium;(3)SO_2 derivatives decreased cGMP levels in the rings, but not significantly; The decrease of cGMP levels was also independent of endothelium;(4)No changes of TXB_2 in rings with or without endothelium were observed;(5)Whether presence or absence of endothelium, cAMP/cGMP and 6-Keto/TXB_2 ratios were increased significantly.

结果:①SO_2衍生物对去甲肾上腺素预收缩的内皮完整和去除内皮的大鼠胸主动脉血管环均呈浓度依赖性舒张作用,且其张力变化在内皮完整与去内皮的血管环之间无显著性差异;②SO_2衍生物可引起血管组织中cAMP、6-Keto(即PGI_2)含量剂量依赖性增加,其增加程度与内皮无关;③SO_2衍生物对血管环cGMP含量呈降低趋势但在统计学上无显著意义,且对去除内皮血管无显著影响;④SO_2衍生物对去内皮或内皮完整血管环的TXB_2含量均无明显影响;⑤无论是否去除内皮,SO_2衍生物均可引起cAMP/cGMP和6-Keto/TXB_2比值显著升高。

Heart malformation, such as PTA, DORV, VSD and aortic arch malformation, were detected when neural crest were taken out before they migrated into 3, 4, 6 pharyngeal gland. Interestingly, the types of malformation were related with the length of neural crest destroyed; PTA was detected if the length exceeds two somites, while DORV would be detected if the length less than two somites. These results indicate that CNCCs are very important to the conotruncal development.

研究发现,如果在迁移之前切除散发到第3、4、6咽弓的神经嵴细胞,就会出现永存动脉干、主动脉骑跨、右室双出口、主动脉弓畸型和室间隔缺损等心血管畸形,且切除的长度与畸形的种类相关,如切除长度大于两个体节可产生永存动脉干,切除长度小于两个体节则产生右室双流出道,由此可见,心脏神经嵴细胞对于心脏圆锥部的发育意义重大。

The true and false cavities of aortic dissection could be displayed on the SE T1WI,T2WI for the B type in 10 of 12 cases.With SE sequence,the true-false cavities did not be showed but the endomembranous pieces could be seen for A type of 2 cases of aortic dissection.

对于SE序列不能区别真假腔的2例A型夹层,轴位T1WI可显示剥离的内膜片。2例主动脉迂曲形成涡流的B型夹层,T1WI和T2WI不能区别真假腔,也不能显示内膜片,加行GR序列轴位扫描,可清晰显示等信号的内膜片。

A small segment of aorta is seen between the normal, smooth-surfaced kidneys.

表面光滑的正常两肾间,可见一小段主动脉。1/150的人会出现部分或全部的单侧或双侧的双输尿管。

In the management of complicated aortic dissections, endoluminal technique is simple, less traumatic, safe and has less complications as compared to the traditional operation.

对复杂的主动脉夹层的治疗,腔内治疗与传统的手术相比,操作简单、损伤小、安全度大、并发症少,且可大大缩短患者的住院时间。

Abstract] Objective To identify the effect of ECG for the etiological diagnosis of heart disease and investigate some differential diagnosis criteria of ECG.Methods ECG findings from 75 cases of excessive volume load of left ventricle were discriminated.QRS amplitude variability was studied from 3 diseases such as mitral and aortic insufficiency and patent ducts arteriosus.

目的 了明确心电图对心脏病病因诊断的作用,探讨ECG的某些鉴别诊断标准方法采用75例左室容量负荷过重病因的心电图鉴别,研究二尖瓣关闭不全、主动脉瓣关闭不全及动脉导管未闭等3 疾病的QRS振幅变化特征。

A new study shows that the minimally-invasive valve bypass is a safe, effective alternative to conventional valve replacement in high-risk elderly patients with aortic stenosis.

一个新的研究成果显示低损伤瓣膜搭桥是一个安全有效在高风险的高龄主动脉狭窄患者中替代传统的心脏瓣膜置换手术的方式。

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推荐网络例句

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。