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主动脉动脉炎

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Methods Arterial bypass with prosthesis - graft was carried out in 15 cases: ascending aorta- bilateral axillar arteries and unilateral ICA bypass in 6 cases, ascending aorta - bilateral axillar arteries bypass in 3 cases, ascending aorta - unilateral axillar arteries and unilateral ICA bypass in 5 cases, and in one case of complicated TA combined with abdominal aorta, ascending aorta- bilateral axillar arteries and unilateral ICA bypass were performed, followed by unilateral axilla - femeral bypass.

方法15例重症头臂型大动脉炎患者经胸行人工血管旁路术,升主动脉-双腋动脉、单颈内动脉架桥6例,升主动脉-双腋动脉架桥3例,升主动脉一单腋动脉、单ICA架桥5例,1例合并腹主动脉闭塞的复合型,一期行升主动脉-双腋动脉、单ICA架桥,二期行单侧腋股搭桥术。

Among them, 20 patients were candidates of valve replacement and 18 PDA and pericarditis had their blood samples taken before operation,and 1,2,24 and 48 hours after closure of thorax for measurement of concentrations of CK、CK-MB and TnT,together with ECG recording. Results Of the 60 patients, concentrations of cTnT before operation were normal; 2 hours after aortic unclamping, the correlation coefficient between cTnT and aortic clamping was r = 0.873( P<0.01), the regression analysis showed Y = 0. 019X-0. 026. Of the 20 patients, ECG showed the myocardium was ischemic; CK、CK-MB and cTnT all rose significantly, reaching the peak after closure of thorax. Of the 18 patients, the ECG and cTnT before operation and after closure of thorax were normal; except 2 patients with pericarditis.

结果 60例瓣膜手术患者术前cTnT均在正常值范围内,主动脉开放后2 h时,阻断时间和cTnT的相关系数为r=0.875(P<0.01),回归方程为Y=0.019X-0.026;其中20例瓣膜手术患者心脏经过阻断后,心电图有缺血性改变,周围血液中的CK、CK-MB和cTnT均有明显升高,分别在关胸后2 h达到高峰,数值分别为术前的12.6、9.2和257倍;18例行动脉导管结扎和心包剥脱术的患者术前和关胸后的心电图和血液中的cTnT均正常,CK和CK-MB除2例心包炎患者关胸后出现明显变化外,余均未见改变。

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