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FTY720 dose-dependently reduced atherosclerotic lesion formation, both in the aortic root and brachiocephalic artery, and almost completely blunted necrotic core formation.

FTY720的剂量依耐性可同时减少主动脉根部和头臂干动脉粥样硬化病变的形成,并且几乎能全部减弱坏死中心的形成。

At the end of the study, body weight, blood pressure and blood lipid were measured, and atherosclerosis of brachiocephalic arteries were determined by histological examinations. Production of superoxide anion and reactive oxygen species were measured in the thoracic aorta of mice using chemiluminescence and histofluorescence techniques.

在实验结束时,测量小鼠体质量、血压及血脂水平;对头臂干动脉粥样硬化病变进行病理学检查;化学发光法及组织荧光法检测小鼠胸主动脉超氧阴离子和活性氧。

Result: TC, TG, LDL-C level in blood serum of quail hyperlipidemia markedly decreased after administered sugarcane alkane alcohol by dose of 30, 15, 7.5 mg·kg-1, proliferation of aorta and brachiocephalic artery tunica intima foam cells was suppressed.

结果:甘蔗烷醇30,15,7.5 mg·kg-1可降低鹌鹑高血脂模型血清中TC,TG,LDL-C水平,抑制主动脉内膜、头臂动脉内膜泡沫细胞的增殖。

The patient was a 66-year-old male who presented with paraparesis. On examination, strength was 5/5 in both upper extremities and 3-4/5 in both lower extremities. Pricking sensation was relatively retarded below the sixth thoracic vertebra on both sides. Fine-touch sensation was limited below the ninth thoracic vertebra on the right side and below the eleventh thoracic vertebra on the left side. Responses to vibration and joint position sense were well preserved. Deep tendon reflexes were increased in his legs. He had voluntary anal contraction and preserved anal and bulbocavernous reflexes. MRI revealed dissection of the descending aorta from T4 to T10 levels with thrombus present in the false lumen, and the thoracic cord was marked atrophy, especially from T6 to T8 levels. To the best of our knowledge, no such case had been reported so far.

这是一位66岁的男性病患,到院时以下半身轻截瘫来表现,检查后发现其双上肢肌力为5/5而双下肢肌力则为3-4/5,刺痛觉在两侧第六胸椎以下异常,轻触觉在右侧第九胸椎与左侧第十一胸椎以下异常,震动觉与本体感觉则皆属正常,深肌腱反射在两下肢均有异常增强的情形,肛门的主动收缩正常且肛门反射与球体海绵体肌反射均正常,核磁共振影像显示降主动脉在T4到T10处有剥离的情形并於伪腔内发现血栓,此外,病患之胸部脊髓则有明显萎缩的现象,以T6到T8处最为明显,就目前可见的文献资料,并无类似的报告被提出。

104 Cases of calcific aortic disease were found by the ultrasonic images in 2490 elderly cadres.

本文分析了在2490名中老年干部中经超声心动图诊断的104例钙化性主动脉瓣病的超声心动图表现。

After age 50 the cause which ismost frequently overlooked is calcific aortic stenosis.

50岁以后最容易疏忽的病因是钙化性主动脉狭窄。

Prof. Shelton: Well it's a very important topic and we are seeing calcific aortic stenosis of the elderly more frequently these days I believe than we used to because people are living longer to have the disease.

Shelton教授:这个话题非常重要,我们现在看到比从前更多的老年患者出现主动脉钙化狭窄,我想这是因为人的寿命比以前更长了。

Atherosclerotic/calcific aortic stenosis, on the other hand, develops at later in life and is a manifestation of diffuse atherosclerosis that commonly affects elderly individuals.

另一方面,动脉粥样硬化/钙化性主动脉瓣狭窄出现的时期更晚,表现为广泛的动脉粥样硬化,常好发于老年人。

Objective To assess the clinical effect of intra-aortic balloon pump in patients with cardiogenic shock due to acute myocardial infarction.

目的 探讨主动脉内球囊反搏在介入治疗急性心肌梗死合并心源性休克患者中的作用。

Objective:To observe the feasibility and efficiency of intra-aortic balloon pump implantation,guided by Echocardiographly in patients with cardiogenic shock.

目的:探讨床旁超声引导下主动脉内气囊反搏植入术的可行性及对心源性休克的疗效。

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