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Using the optimized MDCTA techniques, we prospectively scanned 23 consecutive patients with thoracoabdominal aortic aneurysms (aneurysmal dilatation of thoracic aorta in 7 and abdominal aorta in 10, 3 thoracoabdominal aortic dissecting aneurysms, and 3 aortic dissection) in same period of time.

采用上述MDCTA技术,纳入同期连续性的胸腹主动脉瘤病人作为病例组研究对象进行CT增强扫描,共计23例(胸主动脉瘤7例,腹主动脉瘤10例,胸腹主动脉夹层动脉瘤3例,胸腹主动脉夹层分离3例)。3。

After administration of L-N〓-nitro-Arginine, a specific antagonist of NOS, it was found that the basal and stimulated NO release of blood vessels (aorta, internal carotid, renal and mensenteric artery) was decreased further. The increase of coronary blood flow stimulated by Ach was also reduced further, while the platelet aggregation degree and erythrocyte aggregation index increased significantly. Pathological examination indicated that aortic endothelium was destroyed, the blood vessels in cerebral, cardiac and renal tissues were hypertrophied further and some were almost occluded. The above fin dings resulted in SHR feeded with L-NNA having high incidence of stroke rate and high degree of renal cirrhosis when compared to control SHR. The infarct and hemorrhagic focuci in cerebral tissues, infarct focuci in cardiac tissues, atrophy and hyalinedegeneration of renal glomeruli and degeneration even necrosis of renal tubuli in renal tissues were al so found. The increase ratio of brain and heart to body weight and decrease ratio of kidney to body wei ght further demonstrated that the cerebral, cardiac and renal injuries were aggravated.

在上述结果的基础上进一步给予SHR NOS特异性拮抗剂左旋亚硝基精氨酸后,血管(胸主、颈内、肾及肠系膜动脉)NO基础释放及激动剂刺激释放进一步减少,Ach刺激冠脉流量的增加和胸主动脉内膜NOS活性也进一步减少,血小板聚集程度及红细胞聚集指数显著上升,病理切片显示胸主动脉内皮细胞破坏明显,脑心肾组织内的血管进一步增厚甚至几乎阻塞,导致饲L-NNA的SHR缺血性及出血性脑卒中发生率显著高于对照SHR,脑体重比显著升高;心肌内出现明显的缺血梗塞疤痕灶,心体重比显著升高;肾小球明显萎缩、玻璃样变性,肾小管也变性甚至坏死,使肾硬化程度显著增加呈颗粒性固缩肾,肾体重比也显著减少。

Baekgroud: Spinal cord ischemia reperfusion injury is an serious secondary spinal cord injury. Trauma, arteriosclerosis, vasal abnormality, inflammation, vasal infarct, decompression after the diseases that can bring spinal cord compression, lessening the blood stream of the spinal cord temporarily ,because of clamping the aorta during the operation of aorta, all of which can engender different extent spinal cord ischemia.

背景:脊髓缺血再灌注损伤是严重的脊髓继发性损伤,创伤、动脉硬化、血管畸形、炎症、血管梗塞、各种产生脊髓压迫的疾病减压后以及在主动脉手术中,钳夹主动脉导致脊髓血液供应暂时性减少都可造成不同程度的脊髓缺血再灌注损伤。

Trauma, arteriosclerosis, vasal abnormality, inflammation, vasal infarct,decompression after the diseases that can bring spinal cord compression, lessening the blood stream of the spinal cord temporarily ,because of clamping the aorta during the operation of aorta, all of which can engender different extent spinal cord ischemia.

背景:脊髓缺血再灌注损伤是严重的脊髓继发性损伤,创伤、动脉硬化、血管畸形、炎症、血管梗塞、各种产生脊髓压迫的疾病减压后以及在主动脉手术中,钳夹主动脉导致脊髓血液供应暂时性减少都可造成不同程度的脊髓缺血再灌注损伤。

Results AE from CM had vasodilating effect on the contracti on of mesentery blood capillary in guinea pigs and the contraction of rat thoracic aortic ring induced by l0μmol/L phenylephrine, even under the condition of pre-treating with glibenclamide (1μmol/L) or propranolol (3μmol/L). When the endothelium of the rat thoracic aortic ring was removed, AE from CM had not vasodilating effect hut constrictive effect. AE from CM could also increase the contents of NO, NOS and cNOS in the aortic tissue and had no obvious effect on the NO content in plasma and iNOS in aortic tissue of rats.

结果 桑白皮丙酮提取物有抑制去甲肾上腺素收缩豚鼠肠系膜微血管的作用,抑制苯肾上腺素(10μmol/L)收缩离体大鼠胸主动脉环的作用,预加优降糖或普蔡洛尔(3μmol/L)后仍然有松弛作用;大鼠胸主动脉环去内皮后药物无松弛作用,反而起收缩作用;显著升高血管的NO和NOS、cNOS含量,对大鼠血浆的NO和血管iNOS的含量影响不大。

The treatment group was injected venously with 0.5 mL of TAPP-Co-NO mixed DMSO, and the control group was given with 0.5 mL of DMSO.

选取家兔离体胸主动脉环测TAPP-Co-NO对家兔离体胸主动脉环舒张作用。

Then animals were killed by gas embolism, aorta was separated from the beginning of aortic arch to abdominal aorta crotch. At the end of experiment, the aortas were prepared for measuration of the concentration of ceramide and cholesterol. The pathological changes and plaque area were measured.

第十周实验结束时,用气栓法处死动物,将主动脉全部取下,沿正中线剪开,摄像,同时作主动脉斑块面积分析及HE染色等主动脉病理学检测,并取血管组织用HPTLC测量血管胆固醇的含量。

Sometimes individuals with Marfan syndrome who have had repair of the upper portion of the aorta have enlargement of other parts of their aortas.

有时候个人与马凡氏综合征是那些已修复的上层部分的主动脉有扩大的其他部分,他们的主动脉

All the rabbits were then killed and their aortas were observed by naked eyes and light microscope.

wk后处死所有动物,在肉眼及光学显微镜下观察其主动脉斑块病变程度、主动脉壁粥样硬化的病理形态学改变。

It is limited, however, in visualising the distal ascending, transverse, and descending aortas in a substantial number of patients.

但是,对相当一部分患者而言,它对诊断升主动脉远端、主动脉弓、降主动脉处的病灶作用十分有限。

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This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

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