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Through comparing with authetic samples on HPLC and capillary electrophoresis , 5'-TMP and 5'TpT3'were confirmed as two of the products. These results might be meaningful to the prebiotic synthesis of oligonucleotides in origin of life.

通过在高压液相色谱和毛细管电泳中与标准样品对照证实其中含有5'-TMP和5'TpT3',这为探索生命起源中寡核苷酸的生成提供了新的线索。

To explore the suitable dose of mifepristone as an emergency postcoital contraception,from November 1997 to August 1998,660 health women with unprotected intercourse or contraceptive failure were recruited.

为探索米非司酮作为紧急避孕的合适剂量,本研究对避孕失败或未避孕同房72h 内要求紧急避孕的660例妇女,随机单次服米非司酮10mg 或25m g。

After high-affinity bound phages were obtained, they were subjected to in vitro NMT inhibition assay to identify inhibitor phages.

更重要的是为探索艾滋病和肿瘤等的治疗药物开拓新的途径。

Meanwhile,HDAC1 acetylation level is significantly increased.The overexpression of HDAC1 can promote erythroid cell proliferation and inhibits induced differentiation,the knockdown of HDAC1 or 2 inhibits erythroid cell proliferation and promotes induced differentiation.We also found that HDAC1 affects GATA1 mediated transcription activity.Thus our data revealed that HDAC1 may negatively regulate GATA1 mediated transcription and suggest that the dynamic regulation of GATA1 associated NuRD/MeCP1/HDAC1/HDAC2 complex may determine the onset of erythroid differentiation programs.Moreover,this study will eventually help to design new therapeutic approaches in treatment of leukemia.

研究发现在被诱导分化的小鼠红细胞白血病细胞中与GATA1相结合的HDAC1被乙酰化并失去活性,在血细胞中过表达HDAC1能够促进血细胞的增殖并抑制分化,反之在血细胞中敲除HDAC1或HDAC2能抑制血红细胞的增殖并促进分化,而且HDAC1能够负调控GATA1的转录活性,GATA1与NuRD/MeCP1复合体之间的动态调控,决定血红细胞分化的发生和发展,并为探索白血病的致病机理奠定了理论基础。

In order to research the decay laws of pressure wave and positive pressure actuation duration with the increasing propagation distance under the repeated penetration and explosion of conventional weapons in rock, the tests with varying scale charge and scale distance of the first drilled explosion and the repeated drilled explosion are completed.

为探索常规武器重复打击下岩石介质中压力波及正压作用时间随传播距离的增加而衰减的规律,进行岩石介质中不同比例装约和比例距离的一次钻孔爆炸和重复钻孔爆炸试验。

In this study, NBPT mixed proportionally with urea and NBPT without urea were applied to the soybean plants to analyze the effect of NBPT on the soybean root growth in root vigor, root nodule number and weight, and the activity of nitrogen fixation of root nodule.

为探索利用NBPT提高大豆生长发育的途径,对施用NBPT的大豆,利用氧化还原法,乙炔还原法和凯氏定氮法分别测定了大豆根系活性,根瘤固氮活性和植株含氮量,并测定了大豆根瘤的数量和重量。

The conclusion of this study will be helpful to understand the mechanism of the protein refolding.

本研究结果为探索一个统一的蛋白质折叠机理提供了有益的帮助。

The aim of this work is to investigate the correlation of expression of p120^ctn, RhoA and Cdc42, as well as their influence on clinical pathologic factors in non-small cell lung cancer, and to provide evidences for exploring the biological functions of p120^ctn in tumors.

本研究通过观察p120^ctn与Rho GTP酶中RhoA、Cdc42在非小细胞肺癌中的表达及其对临床病理特征的影响,为探索p120^ctn在肿瘤中的生物学功能提供依据。

In order to detect the targets in team air combat rapidly and effectively, search theory is introduced to the cooperative search analysis.

为探索编队空战中快速有效地搜索空中目标的理论和方法,将搜索论引入到编队对空中目标协同探测研究中。

School of Public Health,Southeast University,Nanjing 210009,ChinaAbstract : Objective:To measure the effect of beta-cypermethrin to the general esterase and acetylcholine esterase activity of German cockroach.

目的:了解高效氯氰菊酯对德国小蠊乙酰胆碱酯酶和非特异性酯酶活性的影响,为探索抗性机制及抗药性生化检测方法提供理论依据。

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In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国,慢性酒精中毒,肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题,你可以随时联系我。

Very pretty, but the airport looks more fascinating The other party wisecracked.

很漂亮,不过停机坪更迷人。那人俏皮地答道。