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临床病理的

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The recognition of this entity is of great importance to both pathologists and clinicians because atypical cellular neurofibroma is clever at masquerading both histologically and cytologically as a sarcoma; therefore, a precise diagnosis of this variant is essential because of the differences in treatment and clinical behavior between benignancy and malignancy.

对於病理医师和临床医师来说,区分出这个纤维神经瘤的变异型非常重要,因为异生细胞纤维神经瘤在组识学上和细胞学上都非常类似肉瘤,因此正确的诊断出这个纤维神经瘤的变异型是必要的,因为临床上对於良性和恶性肿瘤的治疗和肿瘤行为表现是不同的。

objective to investigate the reasons of misdiagnosis on the young patients with non-typical lung cancer,to enhancing the cognition of the disease.methods the data of incidence,clinical manifestation,imageology,bronchoscope,surgical pathologic examination of 32 cases with non-typical lung cancer were analyzed.results 8 cases of 32 patients were misdiagnosed as tuberculosis,7 cases were misdiagnosed as pneumonia,6 cases were misdiagnosed as tuberculosis pleurisy,3 cases were misdiagnosed as omarthritis,2 cases were misdiagnosed as arthritis,2 cases were misdiagnosed as transient ischemic attack,2 cases were misdiagnosed as hemicrania,2 cases were misdiagnosed as intervertebral disk hernia.conclusion the clinical symptom of young patients with non-typical lung cancer was non-typical,and the misdiagnosis rate was high.

目的 探讨不典型青年肺癌误诊的原因,以期提高对本病的认识。方法对32例误诊的青年肺癌(5岁)患者的发病情况、临床表现、影像学检查、支气管镜及手术病理检查进行分析。结果 32例患者中,误诊为肺结核8例,肺炎7例,结核性胸膜炎6例,肩周炎3例,关节炎2例,短暂性脑缺血发作2例,偏头痛2例,椎间盘突出2例。结论青年肺癌临床症状不典型,误诊率较高。

Results among 15 cases, eight cases of Loose bodies about right keen joint;three cases of left keen joint;three cases of both keen joint ;one case of pilosity dissociates bodies;two cases with joint effusion ;six cases with soft tissue swelling.16-slice SCT with 3D reconstruction demonstrated stereoscopic morphology of normal and lesions clearly with MPR correctly demonstrated details and density ,shape and size of lesions.conclusions Sixteen-slice SCT with 3D and MPR techniques can provide valuable spatial information of diseases in bones and joints of wrist and foot which correlated well with that of pathological anatomy .

结果 15例患者中,右侧膝关节游离体8例,左侧3例,双侧3例,多发游离体1例;其中2例伴有关节积液,6例有关节周围软组织肿胀。16层螺旋CT的3-D图像可清晰显示游离体的立体形态,MPR图像则可以多平面,多角度地观察游离体的大小、形态、密度、位置,对病变显示满意。结论多层螺旋CT重建能提供骨关节病变非常有价值的空间关系信息,其表现接近病理解剖,临床应用价值大,有利于临床医师选择治疗方案、制订手术计划。

Abstract] objective to improve the diagnosis of non-ossifying fiboma by analysing its x-ray feature.methods plain x-ray films was performed in all patients.x-ray finding in 8 cases with pathologically-confirmed non-ossifying were analyzed.results the clinical symptom was mild,the lesions occurred usually at the metaphysis of the long bones,the affected bones included femur(n=4),tibia(n=3),humerus(n=1).cortical type was seen in 5 cases,presenting as unilocular or multilacular transparent areas with in the cortex or tightly beneath the cortex,the lesion had a sclerotic margin.which was more obvious at the marrow side.medullary type was seen in 2 cases.the lesion was located at the center of the bone and grew centrally.the tumor was manifested as unilocular or multilocular.tramsparent area with sclerotic border and the bone cortex became thinner with slightly expanding on 11 sides.conclusion plain radiography is the elementally means to detect this disease.based on the typical x-ray signs of non-ossifying fibroma combined with clinical data,correct preoperative diagnosis can be made in most cases.

目的 探讨非骨化性纤维瘤的x线表现以提高诊断水平。方法所有病例均摄有x线平片,分析经病理证实的8例非骨化性纤维瘤。结果临床症状轻,好发于下肢长骨干骺端或骨干,股骨4例,胫骨3例,肱骨1例。皮质型5例,表现为皮质内或紧贴皮质下的单层或多层透亮区,病变向骨内发展进入髓腔,周围有致密硬化带环绕,以髓腔侧明显;髓质型2例,病灶在骨内中央发展,显示为单房或多房透亮区,边缘有硬化,骨皮质菲薄,轻微向周围膨隆。结论 x线为最基本的检查方法,典型病例x线平片结合临床症状即可明确诊断。

The study support this result.No difference within two rhG-CSF treatment groups explaining that receptors were induced on the basis of exist of injury brain tissue, the action is Volant. This pathological change is significance for the clinic therapy. Provid a basis of theory for the clinic application.

本研究结果支持这一结果,用rhG-CSF治疗的二组之间结果无显著差别,说明了rhG-CSF在脑病变存在的基础上诱导受体活化,作用是快速的,这种病理变化对临床治疗有重要意义,为该种方法应用临床提供了理论依据。

Cerebrovascular diseases,characterized by high incidence and mortality,represent one of the most frequently occurred neurological diseases clinically,so it is of vital importance to instruct catechumen to precisely and systematically grasp related knowledge ranging from its pathogenetic mechanisms,clinical manifestations to treatment and prognosis in a short period.

者已从教学手段、教学内容和教学管理体制等方面做了一定的探索和尝试【,但由于多数脑血管病从发病到预后有其内在的特点,且由于我国现有医疗状况的制约,临床初学者尚难在短时间内充分、系统掌握脑血管病的病理发生机制、临床表现、治疗及预后。

Purpose:To investigate clinical significance of extrarenal manifestations of renal cell carcinoma in earlier diagnosis and prognosis estimation of renal cell carcinoma.

目的 :探讨肾癌的肾外表现在肾癌早期诊断及预后评估中的临床意义。方法:对 1988~ 2 0 0 1年经手术和病理检查证实为肾癌的 372例临床资料进行回顾性分析。

Pancreatic hepatoid adenocarcinoma has its own histological characteristics and clinical features, which have not received much concern by our physicians and pathologists. Pancreatic hepatoie adenocarcinoma is a rare variant, and it had its own clinical features, such as aggressive and poor prognosis.

胰腺肝样腺癌具有独特的病理形态和临床特点,是原发性胰腺癌少见的特殊亚型,具有易于复发或转移、预后差的临床特点。

This may be explained by follows: First, Decoction Shenkangling can regulate the homeostasis of NEI network and reduce the increased activity of NF-κB to restrain the action of inflammatory-sclerotic media; Second, it can redress the disequilibrium of the ratio of TXA2/PGI2 to reform the hypercoagulable state; Third, it can enhance albumin and reduce cholesterol and triglyceride; Fourth, it can amend the renal damage and protect the function of renal tubule and stroma to prevent the transformation from MCD to FSGS; Last, it can lessen urine protein in AN rats markedly and relieve the side effects of prednisone.4. NF-κB, TXA2 and PGI2, along with the renal pathomorphology and so on can all be the indexes of the diagnosis of Symptom of "Kidney Deficiency and Blood Stasis" and the application of Methods of "Benefiting the kidney and Promoting blood circulation" in TCM.5. The curative effects on AN rats by treatment of integrating Traditional Chinese Medicine with prednisone are much better than using prednisone only. And the curative effects on AN rats by treatment of matching Decoction Shenkangling, having the function of "Benefiting the kidney and Promoting blood circulation", with Prednisone are much better than using Prednisone only.6. When it referred to decreasing urine protein, cholesterol and triglyceride and increasing albumin, Decoction Zhibodihuang excesses Decoction Taohongsiwu. However, when it referred to regulating the disequilibrium of TXA2/PGI2 and meliorating renal lesion, Decoction Taohongsiwu exceeds Decoction Zhibodihuang.7. The curative effects on AN rats by treatment of matching Methods of "Benefiting the kidney and Promoting blood circulation" with Prednisone overmatches using Prednisone matching Method of "Benefiting the kidney" or Method of " Promoting blood circulation" only.

益肾活血中药肾康灵能显著改善AN鼠的肾虚血瘀证的临床表现和实验指标,这可能与中药肾康灵能调理AN鼠机体的NEI网络功能稳态,降低异常升高的NF-κB活性,抑制免疫炎症/硬化介质环节,纠正失衡的TXA2/PGI2,改善AN鼠血液高凝状态,提高AN鼠的血清Alb,降低Ch和TG,减轻AN鼠的肾脏组织病理学变化,保护肾小管-间质功能,阻止MCD向FSGS转化;显著减轻AN鼠的尿蛋白水平以及减轻激素副作用有关。4、NF-κB、 TXB2和6-keto-PGF1α以及肾脏病理形态学改变等,都可作为中医肾虚血瘀证诊断和益肾活血法应用的客观指标。5、中西医结合干预AN鼠疗效优于单纯激素治疗;强的松配合益肾活血中药肾康灵组的综合疗效显著优于单纯强的松组。6、知柏地黄汤组在降低尿蛋白、提高血清Alb、降低Ch和TG疗效上优于桃红四物汤组;桃红四物汤组在纠正失衡的TXA2/PGI2和减轻肾脏病理损害方面优于知柏地黄汤组。7、激素配合益肾活血法干预AN鼠在一定程度上优于激素配合益肾法或活血法。

All the patients had accepted TP chemotherapy and preponderated over 2 cycles,taxol 135 mg/m2,d1,cisplatin 20 mg/m2,d1-4.The chemotherapy was repeated every 21 days on two cycles.Results Among these 34 patients the complete responsewas 0,partial responsewas 3(8.82%),stable diseasewas 6(17.65%),progressive diseasewas 25(73.53%).The main toxicity,reactions were nausea,vomiting and hematologic toxicity.Conclusions TP regimen on advanced NSCLC after failure of NP show slow effectiveness. non-small cell lung cancer ; chemotherapy ; NP regimen ; TP regimen

本文回顾性分析我科自2002年6月—2004年12月间将应用NP方案进展的晚期NSCLC患者改用TP方案治疗的34例临床资料,观察并比较该方案的疗效、毒副反应。1资料与方法1.1临床资料34例经病理组织学及细胞学证实为NSCLC,男性21例,女性13例,年龄35~78岁,平均年龄54岁;鳞癌20例,腺癌12例,腺鳞癌2例,Ⅲb期24例,Ⅳ期10

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