中间体

Methods 4-Methylacetophenone was used as starting material to give 2-(4-methylphenyl) propionitrile via reduction, chlorination and cyanation. 2-(4-Bromomethylpheny1) propionic acid obtained by hydrolysis and bromination of compound Ⅲ could further provided loxoprofen sodium through four steps.

以4-甲基苯乙酮为原料，经还原、氯化、氰化得到2-（4-甲基）苯基丙腈，然后经水解、溴化得到关键中间体2-（4-溴甲基）苯基丙酸，该中间体再经过4步反应可制得洛索洛芬钠。

Synthesis of PPA are intermediate ester methoxy-pyrimidine main raw material; for quinoline acid synthesis; are prepared quinolones (such as: Pipemidic, Ciprofloxacin quinolinic acid, such as containing the quinolone drugs) of raw materials; also are manufacturing and other chemical products dyes intermediates.

是合成PPA的中间体甲氧基嘧啶酯的主要原料；用于喹啉酮酸的合成；是制备喹诺酮类药物(如：吡哌酸、环丙氟哌酸等含喹啉酮酸的喹诺类药物)的原料；亦是制造染料及其他化工产品的中间体。

61 The agent, broker, trader, distributor, repacker, or relabeler who supplies the API or intermediate to the customer should provide the name of the original API or intermediate manufacturer and the batch number supplied.

17.61 将原料药或中间体提供给客户的代理，经纪人，贸易商，经销商，重新包装者或重新贴签者应当提供所供原料药或中间体的原生产商的名称和原批号。

Intermidiate 1, 2-propanediol-sebacate was synthesized with 1, 2-propanediol and sebacic acid, then a novel degradable elastomer, poly, was synthesized by melt phase polycondensation of 1, 2-propanediol-sebacate and citric acid under under certain conditions.

通过癸二酸与1，2-丙二醇反应，生成中间体癸二酸聚酯二元醇，然后将中间体与柠檬酸在一定条件下熔融缩聚制得了一种可降解弹性体聚癸二酸丙二醇柠檬酸酯。

The segments 〓 and 〓 were coupled via Cadiot-Chodkiewcz reaction to afford the intermediate 〓. After the silyl protective groups were removed by TBAF from 〓, we accomplished the stereoselective total synthesis of the target molecule-(11S, 16S)- Oplopandiol Acetate〓.

通过中间体化合物〓和〓的Cadiot-Chodkiewiza炔炔偶联反应得到了中间体化合物〓，再用TBAF脱除保护基完成了目标化合物〓的首次全合成，确证其绝对构型为11S、16S。

The mechanism of thiocarbonyl compounds with thiourea function group has been proposed according to the photoreaction products.5. Total of one heterocyclothione intermidate and four heterocyclothione compounds have been synthesized and structurally characterized.

根据所得到的产物对具有硫脲基团的硫羰基化合物的光反应机理进行合理的推测。5、合成与表征了1个环硫酮中间体和4个杂环硫酮类化合物，摸索出合成杂环硫酮中间体较佳反应条件。

Firstly the mid-pruduct imidazoline was produced by reaction of naphthenic acid and diethylene triamine, then the corrosion inhibitor amphoteric imidazoline, which is soluble in water, was produced by reaction of imidazoline and sodium monochloroacetate in aqueous solution.

以高纯环烷酸与二乙烯三胺反应合成了中间体咪唑啉，再以去离子水为溶剂，用氯乙酸钠对该中间体进行两性化，制得了水溶性两性咪唑啉缓蚀剂。

A phosphorus-containing triazine oligomer was synthesized from triethyl phosphite, cyanuric chloride ,pentaerythritol and morpholine through three steps.

以亚磷酸三乙酯、三聚氰氯、季戊四醇和吗啉为原料，经3步反应合成了含磷三嗪环低聚物，考察了反应条件对中间体及产物收率的影响，对中间体及产物的结构和热性能进行了表征。

Bezaldehyde was used as protective agent in first method.S-Epichloeohydrin was aminated and acidulated to give(2S)-1-Amino-3-chloro-propanol Salts.The acetylation of (2S)-1-Amino-3-chloro-propanol by acetic anhydride produced the intermediate-N-[2--3-chloropropyl]acetamide.And then at 20℃,in the presence of lithium tert-butoxide,benzyl 3-fluoro-4-morpholinophenyl carbamate react with-N-[2--3-chloropropyl]acetamide to give linezolid in total yield of 43.6%.

路线一采用苯甲醛作保护剂，使S-环氧氯丙烷氨解、酸化生成S-1-氨基-3-氯-2-丙醇盐酸盐，然后经乙酰化反应后，生成中间体-N-[2-乙酰氧基-3-氯丙基]乙酰胺，再用N-(3-氟-4-吗啉苯基)氨基甲酸苄酯和中间体在催化剂叔丁醇锂存在下25℃反应生成利奈唑酮，总产率达到43.6%。

The phenyl acetate was synthesized from phenyl hydroxide and acetyl chloride by direct esterification and the factors influencing the synthesis were studied.Results showed that the optimal conditions were:n(C6H6O):n(C2H3OCl)=1:1.2,the amount of solvent cyclohexane was 40 mL(compared to 0.15 mol C6H6O),the reaction temperature was 20℃,and the reaction time was 5 h.

乙酸苯酯(分子式C8H8O2)是重要的药物中间体，它可以转化得到邻羟基苯乙酮和对羟基苯乙酮的混合物，可用于治疗急慢性黄疸型肝炎、胆囊炎等疾病，其中邻羟基苯乙酮是合成抗心律失常药盐酸普罗帕酮的重要中间体。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。