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Objective: To explore the natural differentiation of neural stem cells and the induced differentiation of neural stem cells by co-culture with mesencephalic cells.

目的:用体外培养方法探索小鼠胚胎神经干细胞的自然分化及与中脑组织细胞共培养下的诱导分化。

Pramipexole and ropinirole increased the number of cultured mesencephalic DA neurons with up-regulation of mRNA and protein levels of TH .

结果: 1。普拉克索和罗匹尼罗促进原代培养的中脑细胞中TH阳性神经元的数量增加,伴随TH的mRNA和蛋白水平升高。

Other cases of congenital hydrocephalus involve a narrowed mesencephalic aqueduct with obstruction to CSF flow.

其他的原发性水脑症也有可能因为中脑导水管的阻滞导致脑脊液流动受阻。

Mesencephalic neural stem cells of rats at different gestational days have different capabilities to differentiate towards dopaminergic neurons.

不同胎龄大鼠中脑的神经干细胞体外诱导向多巴胺能神经元分化的能力不同,以孕12 d诱导分化成多巴胺能神经元比例最高。

Objective To investigate the degeneration of dopaminergic neurons induced by MPP+ in mouse mesencephalic dissociated culture.

目的:探讨1-甲基-4-苯基-四氢吡啶离子(1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine,MPP+)诱导小鼠胚胎中脑原代培养多巴胺能神经元损伤。

OBJECTIVE: This study was designed to observe the differentiation potential of rat mesencephalic neural stem cells at different gestational ages towards dopaminergic neurons.

目的:实验拟观察不同胎龄大鼠中脑神经干细胞体外诱导向多巴胺能神经元分化能力。

The present study utilized a new human mesencephalic cell line, MESC2.10, to study the effect of A53T mutant alpha-synuclein on dopamine homeostasis.

此目前研究利用一新的人中脑的细胞株MESC2.10来研究a-synuclein53T突变物对多巴胺内环境平衡的影响。

This study investigated the effect of transplantation of dopaminergic neurons differentiated from neural stem cells into Parkinson's disease rats, and compared to the transplantation of embryonic mesencephalic DNs.

观察神经干细胞诱导分化的多巴胺能神经元移植治疗帕金森病大鼠的作用,并与胚胎中脑多巴胺能神经元组织移植治疗帕金森病大鼠的疗效进行比较。

Interleukin-1β can promote the differentiation of mesencephalic neural stem cells into dopaminergic neuron with enough amount and mature appearance and function.

白细胞介素1β可明显促进中脑神经干细胞分化为数量足够、形态及功能成熟的多巴胺能神经元。

The results showed that at the concentration of 10-8 mol/L,diethylstilbestrol facilitated fetal rat mesencephalic NSCs proliferation and differentiation, and increased neuronal differentiation.

结果显示:己烯雌酚浓度在10-8mol/L时中脑NSCs增殖、分化明显,并能提高神经元的分化率。

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