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Homozygosity for a haplotype that was identical by descent between two of the affected individuals identified a locus for the disease gene within a 17.4 Mb interval on chromosome 15, a region containing 296 genes.

对两个受累个体完全相同的遗传单倍型纯合性分析发现,疾病基因的基因座在第15号染色体17.4 Mb的区间内,该区域包含296个基因。

Johannsen experimented with the Princess bean and found that if the self-fertillzing parent plants were from a mixed population, then selection did indeed work. He described the offspring of single parent as a ' pure line ' and stated that they were genetically identical. In 1905 he coined the terms ' phenotype ' to describe the outward appearance of an individual and ' genotype ' to describe the genetic makeup of an individual.

约翰逊用菜豆做实验,结果发现:如果自体受精的亲本植株来自一个混合群体,那么选择确实是有效的,而被称为"纯系"的单亲后代则表明它们在遗传上是一致的。1905年他首次采用"表现型"来描述某一个体的外观形状,用"基因型"来描述某一个体的遗传组成。

BACKGROUND: It has great significance to understand individual human leucocyte antigen allele haplotype and genotype in organ allotransplantation.

摘要背景:了解个体的人类白细胞抗原单型和基因型在同种异体器官移植中有重要意义。

The major gene genotype of individual F 2 and F 2:3 was classified into according to their posterior probability.

对F2 个体和F2·3 家系的主基因基因型分类作了估计。

A common carp gynogenetic line including 44 individuals derived from the cross Barbless carp Hebao-cold tolerance red carp was used to construct a linkage map using 445 markers (265 AFLP markers, 127 SSR markers, 37 EST-SSR markers and 16 RAPD markers).

用265个AFLP标记、127个微卫星分子标记、37个EST-SSR标记和16个RAPD标记对大头鲤/荷包红鲤抗寒品系的F2雌核发育群体44个个体进行基因型检测,构建鲤鱼遗传连锁图谱。

There was a significant difference in the overall genotypical distribution between the patients and the controls (P0.05). The risk of suffering from PD was increased 3.8 times in the individuals with T allelic genotype of NQO1 gene.

基因型分布在PD和对照组之间差异有显著意义(P.05),带T等位基因的个体患PD的风险增加3.8倍。

The data byχ~2 were consistent with the separation ratio as 1: 2: 1 χ~2=4.028<χ_(0.05,2~2=5.99, which further conformed that glandless character was controlled by a incomplete dominance gene, Gl_2~e. 2. SSR markers every about 5cM were selected in the chromosome 12 of our lab genetic linkage map to screen the parent plants. The markers with the polymorphism were used to amplify the DNA of 210 F_2 segregating plants selected randomly and recorded the marker genotypes. After eliminating the segregation distortion markers byχ~2 test, other SSR markers were detected by linkage analysis.

二、参照本实验室海陆种间遗传连锁图谱第12染色体上的SSR标记,平均每5cM左右选择一个标记进行亲本多态性的筛选,筛选出具有多态性的标记位点进一步扩增随机抽取的210个F_2群体单株的DNA,鉴定每个个体的标记基因型。X~2检测剔除偏分离标记后进行连锁分析,发现Gl_2~e基因位于CIR362与NAU5079之间,进一步参考图谱上位于CIR362与NAU5079之间的标记加密图谱,最终将其定位在CIR362和NAU2251b、NAU3860b、STV033之间。

Methods: For 4 tetrameric STR loci (D5S818, D8S1179, D18S51and D21S11) genetic research, monoplex PCR methods were established to study the allele frequency and the applicability of forensic medicine.

应用聚合酶链反应,聚丙烯酰胺凝胶电泳及银染分型技术,对延边地区109名朝鲜族无关个体进行群体调查,获得四种基因座的群体遗传学资料。

Farther, the sperm DNA of wild male was extracted from copulated wild female thelycum in three families of the ten.

从其中3个家系的雌性亲虾纳精囊中提取了雄虾精子DNA,微卫星标记显示各家系的子代个体均有一个等位基因与雄性亲虾的基因型相符,且符合孟德尔遗传规律,这为野生中国明对虾雌虾在繁殖季节一对一的繁殖行为提供了遗传学的证据。

Selfing: the two genotypes intersect the same individual.

自交:两个基因型相同的个体相交。

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